Protein Alignment Unc-115b and ablim1

DIOPT Version :10

• Sequence 1: NP_731390.1
• Gene: Unc-115b / 41178
• FlyBaseID: FBgn0260463
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_031762145.1
• Gene: ablim1 / 100170541
• XenbaseID: XB-GENE-6455582
• Length: 839
• Species: Xenopus tropicalis
• Alignment Length: 873
• Identity: 268/873 - (30%)
• Similarity: 342/873 - (39%)
• Gaps: 337/873 - (38%)

  Fly    41 KQKIYCAKCTKKCSGEVLRVADNHFHKACFQCCQCKKSLATGGFFTKDNAYYCIPDYQRLYGTKC 105
            |..|.|.||.:.|.||||||...|||..||.|..|...||.||||.|:..|.|..||||:|||:|
 Frog    95 KPVIRCHKCGEPCKGEVLRVQSKHFHIKCFICKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRC 159

  Fly   106 ANCQQYVEGEVVSTMGKTYHQKCFTCSKCKQPFKSGSKVTNTGKEVLCEQCVTGAPVSPSRQATG 170
            :.|.::||||||:.:|||||..||.|:.||:||..|.:||..|::.||:.|.. .|:||
 Frog   160 SGCGEFVEGEVVTALGKTYHPSCFACTSCKRPFPPGDRVTFNGRDCLCQNCAV-LPMSP------ 217

  Fly   171 GGVSSPAPPAESPTRATAHQQHGSVISHKAHLKEDYDPNDCAGCGELLKEGQALVALDRQWHVSC 235
                       .||                   |..:.:.||||...:|.||||:|||:|||:.|
 Frog   218 -----------GPT-------------------EISNSSSCAGCSREIKNGQALLALDKQWHLGC 252

  Fly   236 FRCKACQAVLNGEYMGKDAVPYCEKCYQKGFGVKCAYCSRFISGKVLQAGDNHHFHPTCARCTKC 300
            |:||:|..||.|||:.||..|||||.||..|||||..|:.||:||||:|||. |:||:||||::|
 Frog   253 FKCKSCGKVLTGEYISKDGSPYCEKDYQLMFGVKCEACNEFITGKVLEAGDK-HYHPSCARCSRC 316

  Fly   301 GDPFGDGEEMYLQGSAIWHPRC-----------------------GPGPSESGIILNGGGGTSSV 342
            ...|.:|||||||||.:|||.|                       .|..|.|..:.:..|  ||:
 Frog   317 NQMFTEGEEMYLQGSTVWHPYCKETTKAEEKLRLLPPPFGSYKPRQPTRSSSESVYSRPG--SSI 379

  Fly   343 VGGASNGN---------------------------------------FTDTECDRMS-------- 360
            .|  |.|:                                       :..|..||.|
 Frog   380 PG--SPGHTICAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYMSTNEDRQSVGEPQSPR 442

  Fly   361 ---SSALSEMYIR--SRTPSFNGSLYSSSRKHYRTVSPGLILREYGRPNAEDISRIYT-YSYLTD 419
               ||..||...|  |.|||..|......|...|:.|.|.|           .|.:|: :||
 Frog   443 SDRSSVHSERSPRTVSPTPSVEGYQDGRDRVIQRSTSQGSI-----------SSPVYSRHSY--- 493

  Fly   420 APHYLRKPIDPYDKTPLSPHFHRPS---------SYATTASNAGSVAGSRPPS------------ 463
            .|...|.|          .|||||.         .|..|:|.:.:::.|||.|
 Frog   494 TPTISRSP----------QHFHRPELLRTGGQRLPYMRTSSFSSTLSDSRPNSPFRHHSILHVKG 548

  Fly   464 -RPHSRTRSAMKVLVDAIRSETP----RPK-----SPGMN----------------------NEE 496
             .|:|...|.:....|: |..||    .||     ..|:|                      :|:
 Frog   549 NEPNSGRNSPIPYRPDS-RPPTPTYAQAPKHFHLPDQGINIYRKPPIYKQHDAAALAAQNSESED 612

  Fly   497 PIELSHYPAAKKPPPGEQPKIERDDFPAPPYPY---TDPERRRRYSDTYKGVPASDDEDENVENG 558
            .|:.|.:|||..|.|.|.||||.:.:|.||...   :||.||....:
 Frog   613 IIKSSKFPAAHAPAPNEVPKIETEYWPGPPSLAAIGSDPRRRSSVRE------------------ 659

  Fly   559 KPNGKVKNGEE-QQRLQREAEQLEKLNSGIGSAIAKDLKEHAKYRKWKQNNLDPRNASRTPSASK 622
                  ::||| |:|.|...|||.|||||:|..|.|:.||
 Frog   660 ------EDGEELQKRRQLHEEQLLKLNSGLGQLILKEEKE------------------------- 693

  Fly   623 EPLYKLRYESPIGASPSRNLDHQKPFYEDEMFDRSTSYRGSLGKSLGNAPSYNAIHSYRSPPKPG 687
                            ||...|....|:                       |....|.::...||
 Frog   694 ----------------SRERTHSSHRYD-----------------------YLQSDSSKTSSLPG 719

  Fly   688 YGFKTTTLPYIRNGF----SSDF----SYGGLGDKTHSTDLSCGKSEASVDSITEGDRRALMGGD 744
            ||         |||.    |:||    |||         |:|.|..|          .::|..|.
 Frog   720 YG---------RNGLHRPVSTDFGHYDSYG---------DISGGVRE----------YQSLPDGH 756

  Fly   745 LPASSTYSGALSYHYPQAGLIRRSLPNM 772
            :||.....|.             |:|||
 Frog   757 VPAMRMDRGV-------------SMPNM 771

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Unc-115b	NP_731390.1	LIM1_abLIM	46..97	CDD:188713	26/50 (52%)
		LIM2_abLIM	102..157	CDD:188714	28/54 (52%)
		LIM3_abLIM	211..262	CDD:188715	32/50 (64%)
		LIM4_abLIM	270..326	CDD:188716	34/78 (44%)
ablim1	XP_031762145.1	LIM1_abLIM	100..151	CDD:188713	26/50 (52%)
		LIM2_abLIM	156..211	CDD:188714	28/54 (52%)
		LIM3_abLIM	228..279	CDD:188715	32/50 (64%)
		LIM4_abLIM	287..342	CDD:188716	33/55 (60%)
		AbLIM_anchor	364..789	CDD:465046	128/566 (23%)
		VHP	804..839	CDD:460493