Protein Alignment Unc-115b and ablim1a

DIOPT Version :10

• Sequence 1: NP_731390.1
• Gene: Unc-115b / 41178
• FlyBaseID: FBgn0260463
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_017214154.1
• Gene: ablim1a / 100003558
• ZFINID: ZDB-GENE-080219-41
• Length: 751
• Species: Danio rerio
• Alignment Length: 783
• Identity: 246/783 - (31%)
• Similarity: 323/783 - (41%)
• Gaps: 249/783 - (31%)

  Fly     4 LIYISIPKHPQTDKTRPIYPST-LGTELRTELGKTGQG-----KQKIYCAKCTKKCSGEVLRVAD 62
            ::|: |||.....:...|.|.. ..||..|.:..|.:.     |..|.||||.:.|.||||||..
Zfish    47 VLYL-IPKQSVKQQLPFINPDDYYMTESLTPVAHTQESHHQTEKPLIRCAKCGELCKGEVLRVQA 110

  Fly    63 NHFHKACFQCCQCKKSLATGGFFTKDNAYYCIPDYQRLYGTKCANCQQYVEGEVVSTMGKTYHQK 127
            .|||..||.|..|...||.||||.|:..|.|..||||::||:|..|.::||||||:.:|||||..
Zfish   111 KHFHIKCFTCKVCGCDLAQGGFFMKNGEYLCTLDYQRIHGTRCNICGEFVEGEVVTALGKTYHPT 175

  Fly   128 CFTCSKCKQPFKSGSKVTNTGKEVLCEQCVTGAPVSPSRQATGGGVSSPAPPAESPTRATAHQQH 192
            ||.|:.||:||.:|.:||..||:.||:.|  ..|:||                 .||
Zfish   176 CFVCTICKRPFPAGDRVTFNGKDCLCQYC--AEPMSP-----------------GPT-------- 213

  Fly   193 GSVISHKAHLKEDYDPNDCAGCGELLKEGQALVALDRQWHVSCFRCKACQAVLNGEYMGKDAVPY 257
                      |:...|:.|||||..:|.||||:||:||||:.||:||||..||.|||:.||..|:
Zfish   214 ----------KDVVGPSSCAGCGRDIKNGQALLALERQWHLGCFKCKACAKVLTGEYISKDGAPF 268

  Fly   258 CEKCYQKGFGVKCAYCSRFISGKVLQAGDNHHFHPTCARCTKCGDPFGDGEEMYLQGSAIWHPRC 322
            ||:.||..|||:|..|.:||:||||:|||. |:||:||||::|...|.:|||||||||.:|||.|
Zfish   269 CERDYQLQFGVQCEACQQFITGKVLEAGDK-HYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPSC 332

  Fly   323 GPGP----------SESGIILNGGGG--------------------------------------- 338
            ...|          |.|..|.:..|.
Zfish   333 KHSPRGEERQRPTRSSSESICSRPGSSIPSSPGHTIYAKVDNEILDYRDLAAIPKVKAIYDIERP 397

  Fly   339 ---------TSSVVGGASNGNFTDTECDRMSSSALSEMYIRSRTPSFNGSLYSSSRKHYRTVSPG 394
                     |:|:.......:..:.:..|..||.:.:...||.|||..|......|..:|:.|.|
Zfish   398 DLINYEPLYTTSLDESEERESVAELQSSRRESSPMPDDRTRSPTPSAEGYYDMRERILHRSTSQG 462

  Fly   395 LILREYGRPNAEDISRIYTYSYLTDAPHYLRKPIDPYDKTPLSPHFHRPSSYATTASNAGSVAGS 459
            .|    |.|         .||.....|...|.|          .|||||        :.|.....
Zfish   463 SI----GSP---------IYSRHNYTPTLSRSP----------QHFHRP--------DQGMNIYR 496

  Fly   460 RPP-SRPHSRTRSAMKVLVDAIRSETPRPKSPGMNNEEPIELSHYPAAKKPPPGEQPKIERDDFP 523
            :|| .:.|.....|                :...:.::.|:.:.:|:|..|.|....|||.|.:.
Zfish   497 KPPIYKQHDSAAFA----------------AQSKSADDIIKSAKFPSAFAPGPDYPTKIETDCWS 545

  Fly   524 APPYPY---TDPERRRRYSDTYKGVPASDDEDENVENGKPNGKVKNGEEQQRLQREAEQLEKLNS 585
            .|.:..   ||..||            |.:|||.             |.|:|.|.:.|.|.|:.|
Zfish   546 FPNFHAALGTDGRRR------------SKEEDEE-------------EIQKRRQIQEEHLNKIQS 585

  Fly   586 GIGSAIAKDLKEHAKYRKWKQNNLDPRNASRTPSASKEPLYKLRYESPIGASPSRNLDHQKPFYE 650
            |:|..|.|:..|..|.|:        |:|                         |:|..|:  ||
Zfish   586 GLGKMILKEEMEKEKIRE--------RHA-------------------------RSLSAQR--YE 615

  Fly   651 DEMFDRSTSYRGSLGKSLGNAPSYNAIHSYRSPPKPGYGFKTTTLPYIRNGF----SSDFS-YGG 710
            ......|.|..|||                     ||||         |||.    |:||: |..
Zfish   616 HGSNQSSPSKTGSL---------------------PGYG---------RNGLHRPQSTDFTQYNS 650

  Fly   711 LGD 713
            .||
Zfish   651 YGD 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Unc-115b	NP_731390.1	LIM1_abLIM	46..97	CDD:188713	27/50 (54%)
		LIM2_abLIM	102..157	CDD:188714	29/54 (54%)
		LIM3_abLIM	211..262	CDD:188715	32/50 (64%)
		LIM4_abLIM	270..326	CDD:188716	33/55 (60%)
ablim1a	XP_017214154.1	LIM1_abLIM	94..145	CDD:188713	27/50 (54%)
		LIM2_abLIM	150..205	CDD:188714	30/56 (54%)
		LIM3_abLIM	222..273	CDD:188715	32/50 (64%)
		LIM4_abLIM	281..336	CDD:188716	33/55 (60%)
		AbLIM_anchor	345..701	CDD:465046	95/446 (21%)
		VHP	716..751	CDD:128458