DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9444 and NRT1:2

DIOPT Version :9

Sequence 1:	NP_001262431.1	Gene:	CG9444 / 41175	FlyBaseID:	FBgn0037730	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	NP_564978.1	Gene:	NRT1:2 / 843321	AraportID:	AT1G69850	Length:	585	Species:	Arabidopsis thaliana

Alignment Length:	581	Identity:	123/581 - (21%)
Similarity:	221/581 - (38%)	Gaps:	134/581 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 WRGERAQLKLAHRSSLPNYGFAPPTIRMKYRYPRAVFFVLATKFFE--AFAANGIRTVLALYLRD 98
            || .||.:|..|...|                  |..|||..:..|  |:.||.  :.|.||||:
plant    16 WR-NRAAVKGRHGGML------------------AASFVLVVEILENLAYLANA--SNLVLYLRE 59

  Fly    99 DLNFTESFSTVVLHIFNFFGQ--FCPIIGAILADSYIGNVRTISGFSFIYAFGWLLLTLTS-LPA 160
            .::.:.|.|  ...:.||.|.  ...::|..|:|::....:.....:.|...|.::||:.: .|:
plant    60 YMHMSPSKS--ANDVTNFMGTAFLLALLGGFLSDAFFSTFQIFLISASIEFLGLIILTIQARTPS 122

  Fly   161 MGLP-------------MVLLVSIALLFIAVGNGSIRACITSLGALQF--KLPEQSVHLAEYFSF 210
            :..|             ...::.:.|..:|:|.|.|:..:.|.||.||  ..|:.....:.:|::
plant   123 LMPPSCDSPTCEEVSGSKAAMLFVGLYLVALGVGGIKGSLASHGAEQFDESTPKGRKQRSTFFNY 187

  Fly   211 YYFVYYFGIFLSKILPPLVRANTQCFDKAECYPAVFGTLGAAFMMAWFIFLVGKWFYKSEKLSDD 275
            :.|....|..::......:..|       :.:...||....|..::..|||.|..||:: |:...
plant   188 FVFCLACGALVAVTFVVWLEDN-------KGWEWGFGVSTIAIFVSILIFLSGSRFYRN-KIPCG 244

  Fly   276 NIL-----------FKFCG------------------CIKTAL--------VEKWRR------RK 297
            :.|           .|.|.                  |:....        :||.|:      |.
plant   245 SPLTTILKVLLAASVKCCSSGSSSNAVASMSVSPSNHCVSKGKKEVESQGELEKPRQEEALPPRA 309

  Fly   298 STKRSNYWLHNA--------VVAYDMGFVNDVSRVLRISKLFIPLPFYFALLAQQDSSWTFQATQ 354
            ....|...|:.|        ::...:..|.||..||::..:|.........|||..:....||..
plant   310 QLTNSLKVLNGAADEKPVHRLLECTVQQVEDVKIVLKMLPIFACTIMLNCCLAQLSTFSVQQAAS 374

  Fly   355 MNTTLMGVTIQPDQAKAVGPIFLFMLIPLWQYITVPLLRRYFNWE--LQPLHSVTVGGIFSAGAF 417
            |||.:..:.|.|........:|:.:|.|::.::.:|..|:....|  :..|..:.||.:.|..|.
plant   375 MNTKIGSLKIPPASLPIFPVVFIMILAPIYDHLIIPFARKATKTETGVTHLQRIGVGLVLSILAM 439

  Fly   418 FCAGALQERIKNSPPQT----------VNIAWQLPQFLLLMMGELLLSIPGLQFAFTQAPTSMKS 472
            ..|..::.:.|.....:          |...|...|:|.|...:|......|::.||:||:||:|
plant   440 AVAALVEIKRKGVAKDSGLLDSKETLPVTFLWIALQYLFLGSADLFTLAGLLEYFFTEAPSSMRS 504

  Fly   473 VVTAAWFLNNAFG----NLIVVLVTEL------------GMLSSQMAEYFFYAVVMLVCII 517
            :.|:..:.:.|.|    ::||.:|..:            ..::....:||::    |:|::
plant   505 LATSLSWASLAMGYYLSSVIVSIVNSITGSSGNTPWLRGKSINRYKLDYFYW----LMCVL 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9444	NP_001262431.1	PTR2	68..524	CDD:225646	116/549 (21%)
		MFS	68..>190	CDD:304372	32/139 (23%)
		MFS	137..488	CDD:304372	88/433 (20%)
NRT1:2	NP_564978.1	MFS_NPF4	29..575	CDD:340972	117/567 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	120	1.000	Domainoid score	I1880
eggNOG	1	0.900	-	-		E1_COG3104
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I1193
OMA	1	1.010	-	-		QHG55282
OrthoDB	1	1.010	-	-		D365203at2759
OrthoFinder	1	1.000	-	-		FOG0000101
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X63
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.880