DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9444 and AT1G27040

DIOPT Version :9

Sequence 1:	NP_001262431.1	Gene:	CG9444 / 41175	FlyBaseID:	FBgn0037730	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	NP_174024.2	Gene:	AT1G27040 / 839593	AraportID:	AT1G27040	Length:	567	Species:	Arabidopsis thaliana

Alignment Length:	588	Identity:	126/588 - (21%)
Similarity:	229/588 - (38%)	Gaps:	122/588 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 WRGERAQLKLAHRSSLPNYGFAPPTIRMKYRYPRAVFFVLATKFFE--AFAANGIRTVLALYLRD 98
            || .:|.|:..|...|                  |..||||.:..|  ||.||.  :.|.|||::
plant    18 WR-NKAALRGRHGGML------------------AASFVLAVEILENLAFLANA--SNLVLYLKN 61

  Fly    99 DLNFTESFSTVVLHIFNFFGQFCPIIGAILADSYIGNVRTISGFSFIYAFGWLLLTLTS-----L 158
            .::.:.:.|:..:..|........::|..|||::..........:.|...|.:|||:.:     :
plant    62 FMHMSLARSSSEVTTFMATAFLLALLGGFLADAFFSTFVIFLISASIEFLGLILLTIQARRPSLM 126

  Fly   159 P------------AMGLPMVLLVSIALLFIAVGNGSIRACITSLGALQFK--LPEQSVHLAEYFS 209
            |            .:|......:.:.|..:::|.|.|:..:.|.||.||.  .|:.....:.:|:
plant   127 PPPCKSSAALRCEVVGGSKAAFLFVGLYLVSLGIGGIKGSLPSHGAEQFDEGTPKGRKQRSTFFN 191

  Fly   210 FYYFVYYFGIFLSKILPPLVRANTQCFDKAECYPAVFGTLGAAFMMAWFIFLVGKWFYKSE--KL 272
            :|.|....|..::......:..|       :.:...||....:..::..:||:|..|||::  :.
plant   192 YYVFCLSCGALVAVTFVVWIEDN-------KGWEWGFGVSTISIFLSILVFLLGSRFYKNKIPRG 249

  Fly   273 SDDNILFK------FCGC-------------IKTALVEKWRRRKST------------KRSNYWL 306
            |....:||      ...|             :::...||...:..|            |..:.||
plant   250 SPLTTIFKVLLAASIVSCSSKTSSNHFTSREVQSEHEEKTPSQSLTNSLTCLNKAIEGKTHHIWL 314

  Fly   307 HNAVVAYDMGFVNDVSRVLRISKLFIPLPFYFALLAQQDSSWTFQATQMNTTLMGVTIQPDQAKA 371
            ...|..     |.||..||::..:|.........|||..:....||..||..::...: |..:..
plant   315 ECTVQQ-----VEDVKIVLKMLPIFGCTIMLNCCLAQLSTYSVHQAATMNRKIVNFNV-PSASLP 373

  Fly   372 VGP-IFLFMLIPLWQYITVPLLRRYFNWELQPLH--SVTVGGIFSAGAFFCAGALQERIKNSPPQ 433
            |.| :|:.:|.|.:.::.:|..|:....|:...|  .:.||.:.|..|...|..::.:.|....:
plant   374 VFPVVFMLILAPTYDHLIIPFARKVTKSEIGITHLQRIGVGLVLSIVAMAVAALVELKRKQVARE 438

  Fly   434 T----------VNIAWQLPQFLLLMMGELLLSIPGLQFAFTQAPTSMKSVVTAAWFLNNAFG--- 485
            .          :...|...|:|.|...:|......|:|.||:||:||:|:.|:..:.:.|.|
plant   439 AGLLDSEETLPITFLWIALQYLFLGSADLFTLAGLLEFFFTEAPSSMRSLATSLSWASLALGYYL 503

  Fly   486 -NLIVVLVTE----------LG-MLSSQMAEYFFYAVVMLVCIILYALLAFDYTLQERKAGMYVR 538
             :::|.:|..          || .|:....:.|::    |:|::  :::.|.:.|...|...|:.
plant   504 SSVMVPIVNRVTKSAGQSPWLGEKLNRNRLDLFYW----LMCVL--SVVNFLHYLFWAKRYKYIS 562

  Fly   539 MDS 541
            ..|
plant   563 TGS 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9444	NP_001262431.1	PTR2	68..524	CDD:225646	115/537 (21%)
		MFS	68..>190	CDD:304372	31/140 (22%)
		MFS	137..488	CDD:304372	87/419 (21%)
AT1G27040	NP_174024.2	PTR2	99..524	CDD:279226	89/437 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	120	1.000	Domainoid score	I1880
eggNOG	1	0.900	-	-		E1_COG3104
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I1193
OMA	1	1.010	-	-		QHG55282
OrthoDB	1	1.010	-	-		D365203at2759
OrthoFinder	1	1.000	-	-		FOG0000101
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X63
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.880