DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9444 and AT1G22570

DIOPT Version :9

Sequence 1:	NP_001262431.1	Gene:	CG9444 / 41175	FlyBaseID:	FBgn0037730	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	NP_173672.1	Gene:	AT1G22570 / 838863	AraportID:	AT1G22570	Length:	565	Species:	Arabidopsis thaliana

Alignment Length:	549	Identity:	130/549 - (23%)
Similarity:	241/549 - (43%)	Gaps:	97/549 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 RAVFFVLATKFFEAFAANGIRTVLALYLRDDLNFTESFSTVVLHIFNFFGQFCPIIGAILADSYI 133
            |:.:|::..:..|.||..||...|..||...|..:.:.:.|.::.::......||:||.:||:|:
plant    35 RSAWFIIGVEVAERFAYFGIACNLITYLTGPLGQSTAKAAVNVNTWSGTASILPILGAFVADAYL 99

  Fly   134 GNVRTISGFSFIYAFGWLLLTLT-SLPAMGL----------PMV---LLVSIALLFIAVGNGSIR 184
            |..|||...|.||..|..||||: ||..|||          |.:   .|...:|..:|:|.|..:
plant   100 GRYRTIVVASLIYILGLGLLTLSASLIIMGLSKQRNDASAKPSIWVNTLFFCSLYLVAIGQGGHK 164

  Fly   185 ACITSLGALQFKL--PEQSVHLAEYFSFYYFVYYFGIFLSKILPPLVRANTQCFDKAECYPAVFG 247
            .|:.:.||.||..  |::.:....:|::::.....||.:|.|:...|:.|..       :...||
plant   165 PCVQAFGADQFDAEDPKEVIARGSFFNWWFLSLSAGISISIIVVAYVQENVN-------WAFGFG 222

  Fly   248 TLGAAFMMAWFIFLVGKWFYK-----SEKLSDDN----------ILFKFCGC--------IKTAL 289
            ......:||..|||:|:..|:     .|:::..|          |.||....        :...|
plant   223 IPCLFMVMALAIFLLGRKIYRYPKGHHEEVNSSNTFARIGRVFVIAFKNRKLRLEHSSLELDQGL 287

  Fly   290 VEKWRRRKSTKRSNYWLHNAVVAYDMGF-------VNDVSRVLRISKLFI-----PLPFYFALLA 342
            :|..:..|...|.|: |..|:::.: |.       |:|...::|:..::|     .:|:     |
plant   288 LEDGQSEKRKDRLNF-LAKAMISRE-GVEPCSGRDVDDAKALVRLIPIWITYVVSTIPY-----A 345

  Fly   343 QQDSSWTFQATQMNTTLM-GVTIQPDQAKAVGPIFLFMLIPLWQYITVPLLRRYFN--WELQPLH 404
            |..:.:|.|...::..:: ||.|......:...:.:.:.:||::.:.:|:.|:...  :.:..|.
plant   346 QYITFFTKQGVTVDRRILPGVEIPAASLLSFVGVSILISVPLYERVFLPIARKITKKPFGITMLQ 410

  Fly   405 SVTVGGIFSAGAFFCAGALQ-ERIK--------NSPPQTV--NIAWQLPQFLLLMMGELLLSIPG 458
            .:..|.:.|......|..:: :|:|        :.|..||  :|.|.:||:|||.|.:|...:..
plant   411 RIGAGMVLSVFNMMLAALVESKRLKIAREHGLVDKPDVTVPMSIWWFVPQYLLLGMIDLFSMVGT 475

  Fly   459 LQFAFTQAPTSMKSV----VTAAWFLNNAFGNLIVVLVT----ELGMLSSQM----AEYFFYAVV 511
            .:|.:.|.||.::|:    ..:|..|::.....::.|:.    :.|..:|.:    .:||::.:.
plant   476 QEFFYDQVPTELRSIGLSLSLSAMGLSSFLSGFLISLIDWATGKDGWFNSNLNRAHVDYFYWLLA 540

  Fly   512 MLVCIILYALLAFDYTLQERKAGMYVRMD 540
            ....|..:|.|...      |..:|.|:|
plant   541 AFTAIAFFAFLFIS------KMYVYRRLD 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9444	NP_001262431.1	PTR2	68..524	CDD:225646	126/531 (24%)
		MFS	68..>190	CDD:304372	43/134 (32%)
		MFS	137..488	CDD:304372	98/419 (23%)
AT1G22570	NP_173672.1	MFS	35..>243	CDD:304372	63/214 (29%)
AT1G22570	NP_173672.1	MFS	147..523	CDD:304372	83/389 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	120	1.000	Domainoid score	I1880
eggNOG	1	0.900	-	-		E1_COG3104
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I1193
OMA	1	1.010	-	-		QHG55282
OrthoDB	1	1.010	-	-		D365203at2759
OrthoFinder	1	1.000	-	-		FOG0000101
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X63
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.880