DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9444 and PTR5

DIOPT Version :9

Sequence 1:	NP_001262431.1	Gene:	CG9444 / 41175	FlyBaseID:	FBgn0037730	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	NP_001331271.1	Gene:	PTR5 / 831725	AraportID:	AT5G01180	Length:	570	Species:	Arabidopsis thaliana

Alignment Length:	574	Identity:	142/574 - (24%)
Similarity:	231/574 - (40%)	Gaps:	151/574 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 RAVFFVLATKFFEAFAANGIRTVLALYLRDDLNFTESFSTVVLHIFNFFGQFC---PIIGAILAD 130
            :|..|:|.|:..|..|..|:.|.|..||...:|. |:.| ....:.|:.|. |   |:|||.:||
plant    30 KACRFILGTECCERLAYYGMSTNLINYLEKQMNM-ENVS-ASKSVSNWSGT-CYATPLIGAFIAD 91

  Fly   131 SYIGNVRTISGFSFIYAFGWLLLTLT-SLPAMGLP------------MVLLVSIALLFIAVGNGS 182
            :|:|...||:.|..||..|..|||:: |:|.: .|            ...:..|||..||:|.|.
plant    92 AYLGRYWTIASFVVIYIAGMTLLTISASVPGL-TPTCSGETCHATAGQTAITFIALYLIALGTGG 155

  Fly   183 IRACITSLGALQF-----KLPEQSVHLAEYFSFYYFVYYFGIFLSKILPPLVRANTQCFDKAECY 242
            |:.|::|.||.||     |..|..   :.:|:::|||...|..::..:...::.|..       :
plant   156 IKPCVSSFGADQFDDTDEKEKESK---SSFFNWFYFVINVGAMIASSVLVWIQMNVG-------W 210

  Fly   243 PAVFGTLGAAFMMAWFIFLVGKWFYKSEK------------------------LSDDNILF---- 279
            ....|....|..:|...|..|..||:.:|                        ..|:::|:
plant   211 GWGLGVPTVAMAIAVVFFFAGSNFYRLQKPGGSPLTRMLQVIVASCRKSKVKIPEDESLLYENQD 275

  Fly   280 --------------KFCGCIKTALVEKWRRRKSTKRSNYWLHNAVVAYDMGFVNDVSRVLRISKL 330
                          |.......|.||.....|...:|:.|....|..     |.::..::|:
plant   276 AESSIIGSRKLEHTKILTFFDKAAVETESDNKGAAKSSSWKLCTVTQ-----VEELKALIRL--- 332

  Fly   331 FIPLPFY-----FALLAQQDSSWTFQATQMNT--TLMGVTIQPDQAKAVGPIF--------LFML 380
               ||.:     ||.:          .:||.|  .|.|.|:  ||  .:||.|        ||..
plant   333 ---LPIWATGIVFASV----------YSQMGTVFVLQGNTL--DQ--HMGPNFKIPSASLSLFDT 380

  Fly   381 I------PLWQYITVPLLRRYFNWE--LQPLHSVTVGGIFSAGAFFCAGALQ---------ERIK 428
            :      |::..:.||..|:|...|  ...|..:.:|.:.|..:...||.|:         ..:.
plant   381 LSVLFWAPVYDKLIVPFARKYTGHERGFTQLQRIGIGLVISIFSMVSAGILEVARLNYVQTHNLY 445

  Fly   429 NSPPQTVNIAWQLPQFLLLMMGELLLSIPGLQFAFTQAPTSMKSVVTAAWFLNNAFGN----LIV 489
            |.....:.|.||:||:.|:...|:...|..|:|.:.|||.:|:|:.:|......||||    .:|
plant   446 NEETIPMTIFWQVPQYFLVGCAEVFTFIGQLEFFYDQAPDAMRSLCSALSLTAIAFGNYLSTFLV 510

  Fly   490 VLVTEL-------GMLSSQM----AEYFFY--AVVMLVCIILYALLAFDYTLQE 530
            .|||::       |.::..:    .:|||:  |.:..:..::|..:|..||.::
plant   511 TLVTKVTRSGGRPGWIAKNLNNGHLDYFFWLLAGLSFLNFLVYLWIAKWYTYKK 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9444	NP_001262431.1	PTR2	68..524	CDD:225646	139/566 (25%)
		MFS	68..>190	CDD:304372	46/136 (34%)
		MFS	137..488	CDD:304372	104/446 (23%)
PTR5	NP_001331271.1	PTR2	97..526	CDD:279226	109/464 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	120	1.000	Domainoid score	I1880
eggNOG	1	0.900	-	-		E1_COG3104
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I1193
OMA	1	1.010	-	-		QHG55282
OrthoDB	1	1.010	-	-		D365203at2759
OrthoFinder	1	1.000	-	-		FOG0000101
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X63
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.880