DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9444 and AT3G25280

DIOPT Version :9

Sequence 1:	NP_001262431.1	Gene:	CG9444 / 41175	FlyBaseID:	FBgn0037730	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	NP_189165.1	Gene:	AT3G25280 / 822122	AraportID:	AT3G25280	Length:	521	Species:	Arabidopsis thaliana

Alignment Length:	563	Identity:	121/563 - (21%)
Similarity:	208/563 - (36%)	Gaps:	149/563 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 WRGERAQLKLAHRSSLPNYGFAPPTIRMKYRYPRAVFFVLATKFFE--AFAANGIRTVLALYLRD 98
            |:|:.|         :|.          |:...||...|......|  .|.|||...|  .|...
plant    12 WKGKEA---------IPG----------KHGGIRAASIVCVVVMMENIVFIANGFNFV--KYFMG 55

  Fly    99 DLNFTESFSTVVLHIFNFFGQ--FCPIIGAILADSYIGNVRTISGFSFIYAFGWLLLTLTS---- 157
            .:::|.  :|....:.||.|.  ...:.|..:|||::.:..|...|..|...|.:|||..:
plant    56 SMHYTP--ATAANMVTNFMGTSFLLTLFGGFIADSFVTHFTTFIVFCCIELMGLILLTFQAHNPK 118

  Fly   158 -LPAMGLPMVLLVSIALLF-----IAVGNGSIRACITSLGALQFKLPEQSVHLAEYFSFYYFVYY 216
             ||........|.| |:||     :|:|.|.::|.:.|.|..|.......: ::.:|.:.||...
plant   119 LLPEKDKTPSTLQS-AILFTGLYAMAIGTGGLKASLPSHGGDQIDRRNPRL-ISRFFDWLYFSIC 181

  Fly   217 FGIFLSKILPPLVRANTQCFDKAECYPAVFGTLGAAFMMAWF---------------IFLVGKWF 266
            .|                      |..||...|.......|.               ||.||..|
plant   182 SG----------------------CLLAVTVVLWIEEKKGWIWSFNISVGILATALCIFTVGLPF 224

  Fly   267 YKSEKLSDDNILFKFCGCIKTALV---------------EKWRRRKSTKRSNYWLHNAVVAYDMG 316
            |:.::.:...:.       |.|:|               |..|...|..::|  .||.:...|..
plant   225 YRFKRPNGSPLK-------KIAIVIISAARNRNKSDLDEEMMRGLISIYKNN--SHNKLKWIDKA 280

  Fly   317 FVN-DVSRV-LRISKLFIP-LPFYFALL------AQQDSSWTFQATQ---MNTTLM-GVTIQPDQ 368
            .:| ::|.. :..::.|:. ||.:.:.:      ||..   ||.|.|   ||..|. ...|....
plant   281 TLNKNISETEVEETRTFLGLLPIFGSTIVMSCCVAQLS---TFSAQQGMLMNKKLFHSFEIPVPS 342

  Fly   369 AKAVGPIFLFMLIPLWQYITVPL------LRRYFNWELQPLHSVTVGGIFSAGAFFCAGALQERI 427
            ..|:..||:.:.|||:::....:      ....||     |..:.:|...|:.:...:..::.:.
plant   343 LTAIPLIFMLLSIPLYEFFGKKISSGNNNRSSSFN-----LKRIGLGLALSSVSMAVSAIVEAKR 402

  Fly   428 KNSPPQT---VNIAWQLPQFLLLMMGELLLSIPGLQFAFTQAPTSMKSVVTAAWFLNNAFGNLIV 489
            |:.....   :::.|.:.|:|:|.:.::|.....|:|.:.:||::|||:.||..:.:.|.|..:.
plant   403 KHEVVHNNFRISVLWLVFQYLMLSVSDMLTLGGMLEFFYREAPSNMKSISTALGWCSTALGFFLS 467

  Fly   490 VLVTEL-----GMLSSQ----------MAEYFFYAVVMLVCII 517
            ..:.|:     |.|..|          ..|.|:    :|:|::
plant   468 TTLVEVTNAVTGRLGHQWLGGEDLNKTRLELFY----VLLCVL 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9444	NP_001262431.1	PTR2	68..524	CDD:225646	116/531 (22%)
		MFS	68..>190	CDD:304372	37/135 (27%)
		MFS	137..488	CDD:304372	89/412 (22%)
AT3G25280	NP_189165.1	MFS	93..486	CDD:304372	93/433 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	120	1.000	Domainoid score	I1880
eggNOG	1	0.900	-	-		E1_COG3104
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I1193
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D365203at2759
OrthoFinder	1	1.000	-	-		FOG0000101
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.870