Protein Alignment CG9444 and SLC15A1

DIOPT Version :9

• Sequence 1: NP_001262431.1
• Gene: CG9444 / 41175
• FlyBaseID: FBgn0037730
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_005064.1
• Gene: SLC15A1 / 6564
• HGNCID: 10920
• Length: 708
• Species: Homo sapiens
• Alignment Length: 667
• Identity: 169/667 - (25%)
• Similarity: 273/667 - (40%)
• Gaps: 209/667 - (31%)

  Fly    65 YRYPRAVFFVLATKFFEAFAANGIRTVLALYLRDDLNFTESFSTVVLHIFNFFGQFCPIIGAILA 129
            :.||.::||::..:|.|.|:..|:|.:|.||..:.:::.::.||.:.|.|.......||:||::|
Human    10 FGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNFISWDDNLSTAIYHTFVALCYLTPILGALIA 74

  Fly   130 DSYIGNVRTISGFSFIYAFGWLLLTLTSLPAM----------GLPM-VLLVSIALLFIAVGNGSI 183
            ||::|..:||...|.:|..|..:.:::|:..:          .||: |:|..|.|..||:|.|.|
Human    75 DSWLGKFKTIVSLSIVYTIGQAVTSVSSINDLTDHNHDGTPDSLPVHVVLSLIGLALIALGTGGI 139

  Fly   184 RACITSLGALQFKLPEQSVHLAEYFSFYYFVYYFGIFLSKILPPLVRANTQC--FDKAECYPAVF 246
            :.|:::.|..||: ..|......:||.:|.....|..||.|:.|::|.. ||  ..|..|||..|
Human   140 KPCVSAFGGDQFE-EGQEKQRNRFFSIFYLAINAGSLLSTIITPMLRVQ-QCGIHSKQACYPLAF 202

  Fly   247 GTLGAAFMMAWFIFLVGKWFYKSEKLSDDNILFKFCGCIKTALVEKWRRR-KSTKRSNYWLHNAV 310
            |...|...:|..:|::|...||..| ...||:.|...||..|:..::|.| |:..:..:||..|.
Human   203 GVPAALMAVALIVFVLGSGMYKKFK-PQGNIMGKVAKCIGFAIKNRFRHRSKAFPKREHWLDWAK 266

  Fly   311 VAYDMGFVNDVSRVLRISKLFIPLPFYFALLAQQDSSWTFQATQMNTTLMGVTIQPDQAKAVGPI 375
            ..||...::.:..|.|:..|:||||.::||..||.|.||.|||.|:..:..:.|||||.:.|..|
Human   267 EKYDERLISQIKMVTRVMFLYIPLPMFWALFDQQGSRWTLQATTMSGKIGALEIQPDQMQTVNAI 331

  Fly   376 FLFMLIPLWQYITVPLLRRY-FNWELQPLHSVTVGGIFSAGAFFCAGALQERIKNS--------- 430
            .:.:::|::..:..||:.:. ||:  ..|..:.||.:.::.||..|..:|..|..:
Human   332 LIVIMVPIFDAVLYPLIAKCGFNF--TSLKKMAVGMVLASMAFVVAAIVQVEIDKTLPVFPKGNE 394

  Fly   431 ----------------------------------------------------------------- 430
                                                                             
Human   395 VQIKVLNIGNNTMNISLPGEMVTLGPMSQTNAFMTFDVNKLTRINISSPGSPVTAVTDDFKQGQR 459

  Fly   431 ----------------------------------------------------------------- 430
                                                                             
Human   460 HTLLVWAPNHYQVVKDGLNQKPEKGENGIRFVNTFNELITITMSGKVYANISSYNASTYQFFPSG 524

  Fly   431 -----------PPQ---------------------------------------TVNIAWQLPQFL 445
                       |||                                       |||:|.|:||:.
Human   525 IKGFTISSTEIPPQCQPNFNTFYLEFGSAYTYIVQRKNDSCPEVKVFEDISANTVNMALQIPQYF 589

  Fly   446 LLMMGELLLSIPGLQFAFTQAPTSMKSVVTAAWFLNNAFGNLIVVLVTELGMLSSQMAEYFFYAV 510
            ||..||::.|:.||:|:::|||::||||:.|.|.|..|.||:||::|...|..|.|.|||..:|.
Human   590 LLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGQFSKQWAEYILFAA 654

  Fly   511 VMLVCIILYALLAFDYT 527
            ::||..:::|::|..||
Human   655 LLLVVCVIFAIMARFYT 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9444	NP_001262431.1	PTR2	68..524	CDD:225646	165/659 (25%)
		MFS	68..>190	CDD:304372	41/132 (31%)
		MFS	137..488	CDD:304372	129/554 (23%)
SLC15A1	NP_005064.1	2A1704	28..670	CDD:273343	161/646 (25%)
		PTR2	81..468	CDD:279226	98/391 (25%)
		Extracellular domain (ECD). /evidence=ECO:0000250|UniProtKB:Q9JIP7	383..584		7/200 (4%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3104
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55282
OrthoDB	1	1.010	-	-		D246723at33208
OrthoFinder	1	1.000	-	-		FOG0000101
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X63
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.790