Protein Alignment CG9444 and Slc15a3

DIOPT Version :9

• Sequence 1: NP_001262431.1
• Gene: CG9444 / 41175
• FlyBaseID: FBgn0037730
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_075531.2
• Gene: Slc15a3 / 65221
• MGIID: 1929691
• Length: 578
• Species: Mus musculus
• Alignment Length: 610
• Identity: 146/610 - (23%)
• Similarity: 242/610 - (39%)
• Gaps: 157/610 - (25%)

  Fly    55 GFAPPTIRMKYRYPR-----AVFFVLATKFFEAFAANGIRTVLALYLRDDLNFT---ESFSTVVL 111
            |...|.:....|.||     |...||..:..|..|..|:.:.|.||| :.|||.   :..|...|
Mouse    14 GERQPLVARGPRGPRRWRRTAAAAVLLVQMLERAAFFGVTSNLVLYL-NSLNFNWDGQQASRATL 77

  Fly   112 HIFNFFGQFCPIIGAILADSYIGNVRTISGFSFIY--AFGWLLLTLTS---------LPAMGLP- 164
            ..........| :|..|||.|:|...|||....:|  |.|.||.|:|:         :|.:.|.
Mouse    78 LFLGASYLLAP-VGGWLADVYLGRFLTISLSLLLYLAASGLLLTTITNDGRRSFCGEMPELPLEP 141

  Fly   165 ---------------MVLLVSIALLFIAVGNGSIRACITSLGALQFKLPEQSVHLA-----EYFS 209
                           ....:.:.||.:|:...|:|:.:||.||      :|.:.|.     .:|:
Mouse   142 ACPSSSCQGSWSSPYCATTLYLVLLLLALAASSVRSTLTSFGA------DQVMDLGRDATRRFFN 200

  Fly   210 FYYFVYYFGIFLSKILPPLVRANTQCFDKAECYPAVFGTLGAAFMMAWFIFLVGKWFYKSEKLSD 274
            ::|:....|..||.::...:..|....   ..|..:.|.:|.||.:  |:|....:..|....|.
Mouse   201 WFYWSINLGAILSLLVVAFIEQNISFL---WGYSIIVGLVGLAFFI--FLFATPVFITKPPTGSQ 260

  Fly   275 DNILFKF-----CGCIKTALVEKWRRRKSTKRSNYWLH----------NAVVAYDMGFVNDVSRV 324
            .:.:.|.     |.|           |:|:.|.:...|          ......||.....:.::
Mouse   261 VSSMLKLAFQNCCPC-----------RRSSSRDSESAHLLPDQRSNQPGPSPQEDMANFQVLVKI 314

  Fly   325 LRISKLFIPLPFYFALLAQQDSSWTFQA----------TQMNTTLMGVTIQPDQAKAVGP----- 374
            |.:....:|   |:.:..|..|::..|.          |..|.:|:   ::.|.:....|
Mouse   315 LPVMVTLVP---YWMVYFQMQSTYVLQGLHLHIPNIFRTNPNISLL---LRSDSSNYRIPEAWLL 373

  Fly   375 ----IFLFMLIPLWQYITVPLLRRYFNWELQP--LHSVTVGGIFSAGAFFCAGALQ-ERIK---- 428
                ..:.:|||:..::..|||.|   .:|.|  |..:.:|..|...:...||.|: ||::
Mouse   374 LANVAVILILIPVKDHLIDPLLLR---CKLLPSSLQKMALGMFFGFTSIIVAGVLEKERLQYIAA 435

  Fly   429 -NSPPQTV----------NIAWQLPQFLLLMMGELLLSIPGLQFAFTQAPTSMKSVVTAAWFLNN 482
             .:.||.:          :|.||:||:||:.:.|:..|||||:||:::||.||:..:...:|..:
Mouse   436 NQTVPQLIGKDLYYAAPLSIWWQIPQYLLIGVSEIFASIPGLEFAYSEAPRSMQGAIMGIFFCLS 500

  Fly   483 AFGNL----IVVLVT----------ELGMLSS-QMAEYFF-YAVVMLVCIILYALLAFDYTLQER 531
            ..|:|    :|.|::          :.|.::: ||..||| .|.:..|..:|:..:
Mouse   501 GVGSLLGSGLVALLSFPGGWMYCPKDFGNINNCQMDRYFFLLAGIEAVTAVLFLWI--------- 556

  Fly   532 KAGMYVRMDSEAEDRDVPSTSRSGS 556
             ||.|.|      .|..|::.||.|
Mouse   557 -AGRYER------TRQDPASQRSSS 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9444	NP_001262431.1	PTR2	68..524	CDD:225646	134/563 (24%)
		MFS	68..>190	CDD:304372	42/156 (27%)
		MFS	137..488	CDD:304372	99/438 (23%)
Slc15a3	NP_075531.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		3/12 (25%)
		PTR2	41..567	CDD:225646	134/574 (23%)
		MFS	179..515	CDD:304372	84/366 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	280..301		2/20 (10%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838877
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3104
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	1	Normalized mean entropy	S5598
OMA	1	1.010	-	-		QHG55282
OrthoDB	1	1.010	-	-		D365203at2759
OrthoFinder	1	1.000	-	-		FOG0000101
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X63
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.800