Protein Alignment CG9444 and SLC15A4

DIOPT Version :9

• Sequence 1: NP_001262431.1
• Gene: CG9444 / 41175
• FlyBaseID: FBgn0037730
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: XP_016874280.1
• Gene: SLC15A4 / 121260
• HGNCID: 23090
• Length: 635
• Species: Homo sapiens
• Alignment Length: 637
• Identity: 144/637 - (22%)
• Similarity: 244/637 - (38%)
• Gaps: 141/637 - (22%)

  Fly    38 GERAQLKLAHRSSLPNYGFAPPTIRMKYRYPRAVF-FVLATKFFEAFAANGIRTVLALYLRD-DL 100
            ||||.|..|.|::      |.......:...||.. .||.|:..|..|..||.:.|.|:|.. ..
Human     9 GERAPLLGARRAA------AAAAAAGAFAGRRAACGAVLLTELLERAAFYGITSNLVLFLNGAPF 67

  Fly   101 NFTESFSTVVLHIFNFFGQFCPIIGAILADSYIGNVRTISGFSFIYAFGWLLLTLTSLPAMGLPM 165
            .:..:.::..|.:|..........|..|||:.:|..|.|.....:|..|.|...|.:.||....:
Human    68 CWEGAQASEALLLFMGLTYLGSPFGGWLADARLGRARAILLSLALYLLGMLAFPLLAAPATRAAL 132

  Fly   166 V----LLVSIA-----------------LLFIAVGNGSIRACITSLGALQ--------------- 194
            .    ||...|                 |:.:.:|..:::|.||..||.|
Human   133 CGSARLLNCTAPGPDAAARCCSPATFAGLVLVGLGVATVKANITPFGADQVSRAPARCPCPCPAP 197

  Fly   195 -----FKLPEQSVHLAE-----------------------------YFSFYYFVYYFGIFLSKIL 225
                 ..||:.....||                             :|:::|:....|..||...
Human   198 AQPQPLPLPQSLPLTAEGAPCPGGLLSSAEESRQQVKDRGPEATRRFFNWFYWSINLGAILSLGG 262

  Fly   226 PPLVRANTQCFDKAECYPAVFGTLGAAFMMAWFIFLVGK--WFYKSEKLSDDNILFK---FCGCI 285
            ...::.|.. |......|.|  .:|.||:    :||.|:  :..|....|....:||   :..|.
Human   263 IAYIQQNVS-FVTGYAIPTV--CVGLAFV----VFLCGQSVFITKPPDGSAFTDMFKILTYSCCS 320

  Fly   286 KTALVEKWRR-------RKSTKRSNYWLHNAVVAYDMGF----VNDVSRVLRISKLFIPLPFYFA 339
            :....|:...       ::|:|:|.:  .:..:::...|    |.||..:::|..:|:.|..|:.
Human   321 QKRSGERQSNGEGIGVFQQSSKQSLF--DSCKMSHGGPFTEEKVEDVKALVKIVPVFLALIPYWT 383

  Fly   340 LLAQQDSSWTFQATQMN-TTLMGVTIQPDQAKAV-----GPIFLFMLIPLWQYITVPLLRRYFNW 398
            :..|..:::..|:..:. ..:..:|..|....|.     ..:.:.:||||...:..|:|||:
Human   384 VYFQMQTTYVLQSLHLRIPEISNITTTPHTLPAAWLTMFDAVLILLLIPLKDKLVDPILRRH--- 445

  Fly   399 ELQP--LHSVTVGGIFSAGAFFCAGALQ-ERIKNSPPQTVN--------------IAWQLPQFLL 446
            .|.|  |..:.||..|...:.|.||.|: :|:.....:|:|              :.||:||:||
Human   446 GLLPSSLKRIAVGMFFVMCSAFAAGILESKRLNLVKEKTINQTIGNVVYHAADLSLWWQVPQYLL 510

  Fly   447 LMMGELLLSIPGLQFAFTQAPTSMKSVVTAAWFLNNAFGN------LIVVLVTELGMLSSQMAEY 505
            :.:.|:..||.||:||::.||.||:|.:...:|..:..|:      |.:|.:..:|.:||. .::
Human   511 IGISEIFASIAGLEFAYSAAPKSMQSAIMGLFFFFSGVGSFVGSGLLALVSIKAIGWMSSH-TDF 574

  Fly   506 FFYAVVMLVCIILYALLAFDYTLQERKAGMYVRMDSEAEDRDVPSTSRSGSI 557
            ......:|:.....||     ...:|.|........:..||..||...|.|:
Human   575 GDKQASLLIPGAKPAL-----ATAQRAAAAATAPYGDVLDRQAPSPRPSSSV 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9444	NP_001262431.1	PTR2	68..524	CDD:225646	128/572 (22%)
		MFS	68..>190	CDD:304372	35/144 (24%)
		MFS	137..488	CDD:304372	101/465 (22%)
SLC15A4	XP_016874280.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3104
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55282
OrthoDB	1	1.010	-	-		D365203at2759
OrthoFinder	1	1.000	-	-		FOG0000101
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X63
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.830