DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmdyn-D7 and Nme8

DIOPT Version :9

Sequence 1:	NP_649926.2	Gene:	nmdyn-D7 / 41174	FlyBaseID:	FBgn0028997	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_853622.2	Gene:	Nme8 / 73412	MGIID:	1920662	Length:	586	Species:	Mus musculus

Alignment Length:	269	Identity:	69/269 - (25%)
Similarity:	114/269 - (42%)	Gaps:	57/269 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 DNKINI--NQGMMVQFSPKMVTQFLSGKDTTDVSS--------SVLMNELLAGPAISLELIGDNV 176
            |:.:|:  |:|..:....::|   ||.::...|..        ..|:..:.:..:..|.|..:|.
Mouse   329 DDVLNVIHNEGFTILMQRQIV---LSEEEARTVCKIHENEEYFDNLIGHMTSNHSYVLALRRENG 390

  Fly   177 VETIKACAQYKSTE---AETPSVKLSPSLEELFESEEIRYGFYYSDNDNDVEMDLKFISEARHSI 238
            ||..|.....|:.|   |..|.     ||...|.|.......:|.             |.::.:.
Mouse   391 VEYWKTLIGPKTIEEAYASHPQ-----SLCVQFASGNFPTNQFYG-------------SSSKAAA 437

  Fly   239 IKECVF---KNTTLAIIKPH-SIKDGLLGDIISEILSNGFRLTAMRMILMARINCEEFY------ 293
            .||...   ..:|||:|||| :.|:.:  :|:..|...||.||.|:.:.:...:..:.|
Mouse   438 EKEIAHFFPPQSTLALIKPHVTHKERM--EILKTIKEAGFELTLMKEMHLTPEHANKIYFKITGK 500

  Fly   294 EVYRGVVPEYIPMVAQLASGVCMCMEIACADPEKKTDREFRNFCGPMDPEIAKLLRPHTLRAKFG 358
            :.|:.|       :..|:.|:.:.|.:.    :.....|:|...||:|||.||||.|.:||||:|
Mouse   501 DFYKNV-------LEVLSLGMSLVMVLT----KWNAVAEWRRMVGPVDPEEAKLLSPESLRAKYG 554

  Fly   359 KSKVQNAVH 367
            ...::||||
Mouse   555 LDILRNAVH 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmdyn-D7	NP_649926.2	DM10	9..97	CDD:128921
		NDK	246..387	CDD:197791	42/129 (33%)
		NDPk7B	246..383	CDD:239875	42/129 (33%)
Nme8	NP_853622.2	TRX_NDPK	11..113	CDD:239246
		NDPk	155..301	CDD:260363
		NDK 1	157..254
		NDK 2	312..452		28/143 (20%)
		NDK	313..450	CDD:197791	27/141 (19%)
		NDPk_TX	313..445	CDD:239879	27/136 (20%)
		NDK	448..581	CDD:197791	42/129 (33%)
		NDPk	448..579	CDD:260363	42/129 (33%)
		NDK 3	453..586		39/124 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0105
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D554381at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820