DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmdyn-D7 and NME4

DIOPT Version :9

Sequence 1:	NP_649926.2	Gene:	nmdyn-D7 / 41174	FlyBaseID:	FBgn0028997	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_005000.1	Gene:	NME4 / 4833	HGNCID:	7852	Length:	187	Species:	Homo sapiens

Alignment Length:	142	Identity:	38/142 - (26%)
Similarity:	59/142 - (41%)	Gaps:	12/142 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 KNTTLAIIKPHSIKDGLLGDIISEILSNGFRLTAMRMILMARINCEEFYEVYRGVVPEYIPMVAQ 309
            :..||..:||..::..|:||:|......||.|..|:|:........|.|:..|. .|.|..::..
Human    37 RERTLVAVKPDGVQRRLVGDVIQRFERRGFTLVGMKMLQAPESVLAEHYQDLRR-KPFYPALIRY 100

  Fly   310 LASG--VCMCMEIACADPEKKTDREFRNFCGPMDPEIAKLLRPHTLRAKFGKSKVQNAVHCTDLP 372
            ::||  |.|..|      .....|..|...|..|...|   .|.|:|..|.....:|.:|.:|..
Human   101 MSSGPVVAMVWE------GYNVVRASRAMIGHTDSAEA---APGTIRGDFSVHISRNVIHASDSV 156

  Fly   373 DDSNLELQYMFK 384
            :.:..|:|..|:
Human   157 EGAQREIQLWFQ 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmdyn-D7	NP_649926.2	DM10	9..97	CDD:128921
		NDK	246..387	CDD:197791	38/141 (27%)
		NDPk7B	246..383	CDD:239875	37/138 (27%)
NME4	NP_005000.1	NDK	38..172	CDD:197791	38/141 (27%)
NME4	NP_005000.1	NDPk_I	38..167	CDD:239876	37/138 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0105
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810