DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmdyn-D7 and NME1

DIOPT Version :9

Sequence 1:	NP_649926.2	Gene:	nmdyn-D7 / 41174	FlyBaseID:	FBgn0028997	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_937818.1	Gene:	NME1 / 4830	HGNCID:	7849	Length:	177	Species:	Homo sapiens

Alignment Length:	152	Identity:	37/152 - (24%)
Similarity:	65/152 - (42%)	Gaps:	29/152 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 TLAIIKPHSIKDGLLGDIISEILSNGFRLTAMRMILMARINCEEFY------EVYRGVVPEYI-- 304
            |...|||..::.||:|:||......||||..::.:..:....:|.|      ..:.|:| :|:
Human    32 TFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPFFAGLV-KYMHS 95

  Fly   305 -PMVAQLASGVCMCMEIACADPEKKTDREFRNFCGPMDPEIAKLLRPHTLRAKFGKSKVQNAVHC 368
             |:||.:..|:.:.          ||.|.......|.|.      :|.|:|..|.....:|.:|.
Human    96 GPVVAMVWEGLNVV----------KTGRVMLGETNPADS------KPGTIRGDFCIQVGRNIIHG 144

  Fly   369 TDLPDDSNLELQYMF---KIID 387
            :|..:.:..|:...|   :::|
Human   145 SDSVESAEKEIGLWFHPEELVD 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmdyn-D7	NP_649926.2	DM10	9..97	CDD:128921
		NDK	246..387	CDD:197791	36/150 (24%)
		NDPk7B	246..383	CDD:239875	35/143 (24%)
NME1	NP_937818.1	PTZ00093	30..176	CDD:173387	37/152 (24%)
NME1	NP_937818.1	NDK	30..164	CDD:278749	36/148 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0105
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810