DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmdyn-D7 and nme5

DIOPT Version :9

Sequence 1:	NP_649926.2	Gene:	nmdyn-D7 / 41174	FlyBaseID:	FBgn0028997	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_001002516.1	Gene:	nme5 / 436789	ZFINID:	ZDB-GENE-040718-221	Length:	217	Species:	Danio rerio

Alignment Length:	167	Identity:	46/167 - (27%)
Similarity:	82/167 - (49%)	Gaps:	22/167 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   219 DNDNDVEMDLKFISEARHSIIKECVFKNTTLAIIKPHSI-KDGLLGDIISEILSNGFRLTAMRMI 282
            :||:    ..|.:.|.|       :|...|||:|||.:| |...:.||   ||.:||.:...|.:
Zfish     2 ENDD----PQKLMPEPR-------IFVERTLALIKPDAIHKTDEIEDI---ILQSGFTILQKRRL 52

  Fly   283 LMARINCEEFYEVYRGVVPEYIP-MVAQLASGVCMCMEIACADPEKKTDREFRNFCGPMDPEIAK 346
            .::...|.:||..:.|.:  :.| :.|.::||..:.:.:|    ..:....::...||:....|:
Zfish    53 QLSPEQCSDFYAEHYGKL--HFPHLTAFMSSGPVVALALA----RDQAIATWKAIMGPVSSIKAR 111

  Fly   347 LLRPHTLRAKFGKSKVQNAVHCTDLPDDSNLELQYMF 383
            ...|..|||:||...::||||.::....:..|:::||
Zfish   112 ETHPDCLRARFGTCDLRNAVHGSETFSAAEREIRFMF 148

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmdyn-D7	NP_649926.2	DM10	9..97	CDD:128921
		NDK	246..387	CDD:197791	40/140 (29%)
		NDPk7B	246..383	CDD:239875	38/138 (28%)
nme5	NP_001002516.1	NDK	18..153	CDD:278749	40/140 (29%)
		NDPk5	18..149	CDD:239880	40/140 (29%)
		Dpy-30	161..202	CDD:253069
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0105
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D554381at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820