DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmdyn-D7 and Nme2

DIOPT Version :9

Sequence 1:	NP_649926.2	Gene:	nmdyn-D7 / 41174	FlyBaseID:	FBgn0028997	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_001070997.1	Gene:	Nme2 / 18103	MGIID:	97356	Length:	152	Species:	Mus musculus

Alignment Length:	152	Identity:	40/152 - (26%)
Similarity:	67/152 - (44%)	Gaps:	29/152 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 TLAIIKPHSIKDGLLGDIISEILSNGFRLTAMRMILMARINCEEFY------EVYRGVVPEYI-- 304
            |...|||..::.||:|:||......||||.||:.:..:..:.::.|      ..:.|:| :|:
Mouse     7 TFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGLV-KYMNS 70

  Fly   305 -PMVAQLASGVCMCMEIACADPEKKTDREFRNFCGPMDPEIAKLLRPHTLRAKFGKSKVQNAVHC 368
             |:||.:..|:.:.          ||.|.......|.|.      :|.|:|..|.....:|.:|.
Mouse    71 GPVVAMVWEGLNVV----------KTGRVMLGETNPADS------KPGTIRGDFCIQVGRNIIHG 119

  Fly   369 TDLPDDSNLELQYMFK---IID 387
            :|..:.:..|:...||   :||
Mouse   120 SDSVESAEKEIHLWFKPEELID 141

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmdyn-D7	NP_649926.2	DM10	9..97	CDD:128921
		NDK	246..387	CDD:197791	38/150 (25%)
		NDPk7B	246..383	CDD:239875	36/143 (25%)
Nme2	NP_001070997.1	Interaction with AKAP13. /evidence=ECO:0000250\|UniProtKB:P22392	1..66		18/59 (31%)
Nme2	NP_001070997.1	PTZ00093	3..151	CDD:173387	40/152 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0105
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810