DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmdyn-D7 and nme9

DIOPT Version :9

Sequence 1:	NP_649926.2	Gene:	nmdyn-D7 / 41174	FlyBaseID:	FBgn0028997	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	XP_021334262.1	Gene:	nme9 / 100037319	ZFINID:	ZDB-GENE-070410-39	Length:	665	Species:	Danio rerio

Alignment Length:	315	Identity:	72/315 - (22%)
Similarity:	134/315 - (42%)	Gaps:	77/315 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 DTTRTN----LAKYRKKGFVLLKNNMWTKHLGKFLKTLIDNKININQGMMVQFSPKMVTQFLSGK 147
            |..|.|    |::.|:.||                      ::.:.:.:|:  :.:.|..|.|..
Zfish   323 DAARENREEILSRIRQAGF----------------------RVAMQKELML--TEEQVRLFYSTH 363

  Fly   148 DTTDVSSSVLMNELLAGPAISLELIGDNVVE----------TIKACAQYKSTEAETPSVKLSPSL 202
            ...:..:| ||..:.:|..::|.|:.:..||          .|||       :.|.|.     ||
Zfish   364 VEEEYFNS-LMENMTSGLVLALALVKEGAVEHWRNILGPKDPIKA-------KNEQPD-----SL 415

  Fly   203 EELFESEEIRYG-FYYSDNDNDVEMDLKFISEARHSIIKECVFKNTTLAIIKP---HSIKDGLLG 263
            ...|..|..... .:.|.:..:.|.::.|...           ...|||:|||   |.      .
Zfish   416 RAQFSVENSSINQLHGSSSSEEAEKEISFFFP-----------PEDTLAVIKPDTQHK------E 463

  Fly   264 DIISEILSNGFRLTAMRMILMARINCEEFYEVYRGVVPEYIPMVAQLASGVCMCMEIACADPEKK 328
            :|:.||.:.||.::.::..:::|...||||:.:| ..|.:..:|..:..|.|..:.:.    ::.
Zfish   464 EILEEIQAQGFTISQLKDTILSREMAEEFYKEHR-EKPFFSQLVDYMCRGPCTMLVLT----KEN 523

  Fly   329 TDREFRNFCGPMDPEIAKLLRPHTLRAKFGKSKVQNAVHCTDLPDDSNLELQYMF 383
            ..:|:|...||.||:.|:|..|.:|||:|.|..::||||.:...:.::.:::::|
Zfish   524 AVQEWRAAMGPTDPDQARLTAPESLRARFAKDVLENAVHGSSNTEHADQKIKFIF 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmdyn-D7	NP_649926.2	DM10	9..97	CDD:128921	4/13 (31%)
		NDK	246..387	CDD:197791	41/141 (29%)
		NDPk7B	246..383	CDD:239875	40/139 (29%)
nme9	XP_021334262.1	TRX_NDPK	11..112	CDD:239246
		NDPk_TX	161..296	CDD:239879
		NDPk_TX	314..446	CDD:239879	31/159 (19%)
		NDPk_TX	449..578	CDD:239879	40/139 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D554381at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920