DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p23 and hacd3

DIOPT Version :9

Sequence 1:	NP_001247010.1	Gene:	p23 / 41173	FlyBaseID:	FBgn0037728	Length:	184	Species:	Drosophila melanogaster
Sequence 2:	NP_001038449.1	Gene:	hacd3 / 393441	ZFINID:	ZDB-GENE-040426-1200	Length:	359	Species:	Danio rerio

Alignment Length:	134	Identity:	45/134 - (33%)
Similarity:	70/134 - (52%)	Gaps:	12/134 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSAAAGLIPPPVSWAQRNDLIYVIIDV-ECKDIEHKVTEKTFTFKGV-NVLDPSKKYEVTLNFLH 63
            |||    :.|.|.||||:..||:.::: :.:|:...|.|....|:|. :......:||.:|.||.
Zfish     1 MSA----LTPHVYWAQRHGEIYLRVEISDAQDLSIGVEENILQFRGQGHGAKGENEYEFSLEFLK 61

  Fly    64 EVDPEKVTSKNIGRCLEFTIPKKAAGPYWSSLTTDKTKLHFLKANFAKWRDESDDE----EGDQK 124
            .|.|| |..|:..|.:..|: :|....:|:.||..:.|..||..:|.:|.||||.|    |.::|
Zfish    62 PVKPE-VKHKSTQRQVNITV-RKQEEVWWNRLTKQEKKPLFLAPDFDRWLDESDAEMELREKEEK 124

  Fly   125 DNSM 128
            .|.:
Zfish   125 INKV 128

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p23	NP_001247010.1	p23_hB-ind1_like	10..117	CDD:107222	36/108 (33%)
hacd3	NP_001038449.1	p23_hB-ind1_like	6..113	CDD:107222	36/108 (33%)
hacd3	NP_001038449.1	PTPLA	192..346	CDD:282269
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1673
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940