Protein Alignment Nepl12 and Nepl19

DIOPT Version :9

• Sequence 1: NP_649924.1
• Gene: Nepl12 / 41172
• FlyBaseID: FBgn0037727
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Alignment Length: 758
• Identity: 172/758 - (22%)
• Similarity: 313/758 - (41%)
• Gaps: 164/758 - (21%)

  Fly     8 LISLMLLWVIVAA---VLTDCEARSLVDRSENSDSNGSSTNRSAAEYQLQEYAEF--MKSYMNQS 67
            |:.|:||.::.:.   :||...|..|  |.:..:...|.:|.||...:|...::.  |:|||.|.
  Fly    10 LLQLLLLHLVGSGRGHLLTGQPAIDL--RIQAREQLISQSNDSAYVQRLMRLSKSAEMRSYMQQD 72

  Fly    68 VEPCENFYEYACGNYRNVKPDRYSPGSRSNLGDVTYTLIDITEQLLGRMDLAEALNV-SSELAV- 130
            .:.|||||:|:|||:..:.|...:....:|...:........:|.|    :.:..|| :.|:||
  Fly    73 ADACENFYDYSCGNWPQINPANDAYPRETNFVQLLLKAYSHKQQRL----MEQPANVETDEVAVL 133

  Fly   131 -AQRFYNACLGANLHPFNAADPAYLSLIRSIGGFP--AVDGDAWKASNFNWINMSAHL-ANYGAN 191
             .:.||.:||.....|.:........::...|..|  ::.|..|.|..|:|::..|.: ..||.:
  Fly   134 RLKEFYASCLLFRQVPEDLYRRQLQEIVADFGRMPVLSLPGQEWPAEEFDWLDTVARIKRQYGFD 198

  Fly   192 GLI--RETLQLRYPFEPYTKLPELG--------FDHIIVH---EENISRNTTRAFRLNEERMHGY 243
            .|:  :::....|..:|...|||..        .:|:..|   :..::..|.|.....|:::...
  Fly   199 ILLLFQQSADRIYVGQPKQILPEANRKAVAEDIANHLERHLGVDPKVAVTTAREITEFEQKIAAI 263

  Fly   244 L--RAFGL------PEDRIREAIAGVFAFWRDALEIPPQCEVFDPYRIKRVFPQSEYYYNISWSG 300
            :  |..|:      |.|             .|.:::....:..:....:.:......|.::
  Fly   264 MVDRRVGVMSKLYTPSD-------------ADYVDVSKLTQFVETVLDRELLANESLYQHV---- 311

  Fly   301 LHSTNKLFCDFYYVELDKVCAR---HRKAVANYLAMKLLYRFDPKLKAPRYQRNYCSVTLYQS-M 361
                     ..|.:::|::...   |  .:|||:..:||..|       .|:|....|....| :
  Fly   312 ---------PDYLMKIDELVTETPPH--VLANYVFNELLKHF-------YYERAESVVEQCVSRV 358

  Fly   362 RFLFNKL---YMANNFSEAKRLEMSEMV-RELRKSLRKALED--ADWLDAESRARALLKESRIQP 420
            |.||.:|   .:...:.:...|:...:| ::|::|.|..|::  |:||..|:|
  Fly   359 RDLFGELLDHMLFEQYEDEGTLKDIYVVWQQLQRSFRGVLQNSSANWLVPETR------------ 411

  Fly   421 RIGSFQDDALSDRIIREINSLKVIEDRYAETNINLQHLVVQINRFSSRHFQELTNDTKPQKILTG 485
                       ::::.::|:..::.:.|||.|            |:.| ::||  ..||:..|..
  Fly   412 -----------EQLLEQLNTTSLVINGYAEVN------------FTQR-YEEL--HLKPRDYLHN 450

  Fly   486 LQVGAGYYTPDNSINVMAGVVEPPI----------------YQRHLPISLKFGTLGFIVGHELIH 534
            |:....:.:....:.....|...|:                :.|:.|.::::|:||.::..:|.|
  Fly   451 LRTILNHQSLRVKVKTQTSVTYDPVGKRVLLPVALLQPNFLWSRYYPKAVRYGSLGTLLAQQLAH 515

  Fly   535 GFDTTSSYFDGNGHMESLLSEISQQALEDRAECYMDYYGKYQVPEISRRVNG----KTTLD-ENI 594
            ..:..|.: |.....|          ...|..|:.:.||:.       |:||    ::.|. |||
  Fly   516 SLEDASKW-DAKSFAE----------YSKRKSCFKEQYGRL-------RLNGHYLPESDLQAENI 562

  Fly   595 ADNSGLRQALTAYRSHRQQLLEHPGQERISDAMPGLDLTPEQLFFLGFAQLFCSHYEEEHYWKGL 659
            |||..::   .||.::|:.|.|.......|:::|.|:|...:||||.||||:|:...|:...|..
  Fly   563 ADNLAIQ---VAYHAYRRLLAELDPSFLGSESLPQLNLGSRRLFFLSFAQLWCNDANEQFRDKQS 624

  Fly   660 SDVHTFDQFRVLGVLSNSEDFFHAYNCSVGSGMRPGAKTCRLW 702
            ..:.|.:..||||.|||...|...:||...|.|....| |:|:
  Fly   625 LFLGTPNALRVLGALSNFRAFGRDFNCGTASRMTSPQK-CQLF 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl12	NP_649924.1	M13	68..700	CDD:189000	151/689 (22%)
Nepl19	NP_651644.1	PepO	67..657	CDD:226118	153/687 (22%)
		M13	73..664	CDD:189000	151/689 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451257
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850