Protein Alignment Nepl12 and Nepl16

DIOPT Version :9

• Sequence 1: NP_649924.1
• Gene: Nepl12 / 41172
• FlyBaseID: FBgn0037727
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Alignment Length: 722
• Identity: 145/722 - (20%)
• Similarity: 269/722 - (37%)
• Gaps: 211/722 - (29%)

  Fly    57 AEFMKSYMNQSVEPCENFYEYACGNYRNVKPDRYSPGSRSNLGDVTYTLIDITEQLLGRMDLAEA 121
            |..:::.:|.:.:||..|.:::|  :||. |::    :.:||.::..:...:..|:|   .|.:.
  Fly   164 ASSIQARLNWNKDPCTEFKKFSC--WRNT-PNK----NITNLIEMGNSQKSVDSQML---YLFQN 218

  Fly   122 LNVSSELAVAQRFYNACL-----GANLHPFNAADPAYLSLIRSIGGFPAVDGDAWKASNFNWINM 181
            ..::....:....:.:||     ...:|          .:..|:||:..| |....:|....|
  Fly   219 KIMNGSFGILHNLFESCLQQTTNSTVMH----------RIFDSLGGYLPV-GSVGPSSIAPLI-- 270

  Fly   182 SAHLANYGANGLIRETLQLRYPFEPYTKLPELGFDHIIVHEENISRNTT---RAFRLNEERMHGY 243
             |.:.:.|.:.|:.....|.|...|          ||::.....|.::|   |..|....:
  Fly   271 -AKIYDLGPSPLVDLYHDLSYGRRP----------HILLIISGPSTSSTILERKIRWMSPK---- 320

  Fly   244 LRAFGLPEDRIREAIAGVFAFWRDALEIPPQCEVFDPYRI------------------------- 283
                 .|..|||:.:..:.|   |.:      |.|.||.:
  Fly   321 -----APPSRIRQGVPKLLA---DLI------ENFLPYFVSYAQRVSEKDTIFEFIKDLNKLQVE 371

  Fly   284 --KRVFPQSEYYYNIS------------------WSG---LHSTNKLFCDFYYVELDKVCARHRK 325
              :|.|..|...||:|                  |||   :.:::      |...|:....::..
  Fly   372 HSRRGFWDSTVLYNVSSLQDLYPVLNWTLLIPQNWSGPIVVRNSD------YLKALEYFLTKYPT 430

  Fly   326 AVA-NYL----AMKLLYRFDPKLKAPRYQRNYCSVTLYQSMRFLFNKLYMANNFSE-----AKRL 380
            .|| |.|    |:::|.|..|..:.       |:.:...::..|.:.||:|.:.||     .||.
  Fly   431 RVAHNSLLLLSALQILPRDYPSPEV-------CTRSTMWALPELSSSLYIAQHSSEDLKDTTKRA 488

  Fly   381 EMSEMVRELRKSLRKALEDADWLDAESRARALLKESRIQPRIGSFQDDALSDRIIREINSLKVIE 445
            |:      :.|||:..|:.|..|    :..||:|.|.::.:..:::..:.:..:::.:..|.:..
  Fly   489 EI------IFKSLKAHLKRAPSL----KGAALVKLSALKIQSQTWEGFSNTTDLLKSLQPLNITS 543

  Fly   446 DRYAETNINLQHLVVQINRFSSRHFQELTNDTKPQKI-LTGLQVGAGYY---------TPDNSIN 500
            :.:.:.       :::|.:         .|..:|..| |.|....|..|         |..:||.
  Fly   544 ECWFQN-------ILEIYK---------KNKLEPNDISLNGGSHDAWAYPIVSTIFYDTLSHSIV 592

  Fly   501 VMAGVVEPPIYQRHLPISLKFGTLGFIVGHELIHGFDTTSSYFDGNGHMESLLSEISQQALEDRA 565
            |...|:..|.:...||..|.:.::|..:..|:                :.|:.....::|:
  Fly   593 VPLSVILIPYFNAVLPPYLHYASVGVSIAKEI----------------LRSITKSFDEKAM---- 637

  Fly   566 ECYMDYYGKYQVPEISRRVNGKTTLDENIADNSGLRQALTAYRSHRQQLLEHPGQERISDAMPGL 630
            .|         ||......:..:.:|  |..:||..|  .:|.|    :|...|..:....:|||
  Fly   638 RC---------VPHSVNIFSNYSRMD--ILIHSGGMQ--ISYHS----MLSLTGPIKGMARLPGL 685

  Fly   631 DLTPEQLFFLGFAQLFCSHYEEEHYWKGLSDVHTFDQFRVLG-VLSNSEDFFHAYNCSVGSGMRP 694
            :|||.|:|||..||..|:   |.:|....::...||  .:|| :::........:.|..|| |..
  Fly   686 NLTPTQIFFLVSAQELCA---ESNYLGIDTNAPEFD--NILGWLVAQGGSATEVFKCPSGS-MIN 744

  Fly   695 GAKTCRL 701
            ..|||.:
  Fly   745 VQKTCNV 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl12	NP_649924.1	M13	68..700	CDD:189000	142/708 (20%)
Nepl16	NP_001097912.1	GluZincin	176..749	CDD:301352	141/706 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910