Protein Alignment Nepl12 and Nepl15

DIOPT Version :10

• Sequence 1: NP_649924.1
• Gene: Nepl12 / 41172
• FlyBaseID: FBgn0037727
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Alignment Length: 756
• Identity: 171/756 - (22%)
• Similarity: 289/756 - (38%)
• Gaps: 228/756 - (30%)

  Fly    48 AAEYQLQ----EYAEFMKSYM-NQSVEPCENFYEYACGNYRNVKPDRYSPGSRSNLGDVTYTLID 107
            ||.|.:.    ..|..:|:|| ::..:.|.|||.|||.|:..:.|.|.|. :|:|.      |.:
  Fly    29 AANYSIDILRLAKAAHIKAYMGDEKEQACNNFYNYACANWPRLHPARKSK-TRTNY------LEE 86

  Fly   108 ITEQLLGR-MDLAEALNVSSELAVAQR---FYNAC-LGANLHPFNAADPAYLSLIRSI----GGF 163
            :.|..:.: .|:.::....:|.:..::   ||.:| |..|      ...:.|:.::::    ||:
  Fly    87 LQELYIRKSADMLKSATRGAENSADRQLKYFYGSCRLQTN------DTRSALNTLQNVTDFRGGW 145

  Fly   164 PAVDGDAWKASNFNWINMSAHLANYGANGLIRETLQLRYPFEPYTKLPELGFDHIIVHEENISRN 228
            |.:...:|....::|:.:.|:|..                        :||.|..|..|..:.
  Fly   146 PEIRVASWYQYEYDWLQVVANLKR------------------------KLGVDIFIGLEVILD-- 184

  Fly   229 TTRAFRLNEERMHGYLRAFGLPE------DRIREAIAGVFAFWRDALEIPPQCEVFDPYRIKRVF 287
                  ..||:||..  ..|.|:      ..:.....|....:..::|          .::|..|
  Fly   185 ------YKEEKMHRL--KIGAPQFPMSRRHYLHPHFEGTREIYERSIE----------NKLKLYF 231

  Fly   288 P-QSEYY--------------------YNISWSGLHSTNK----------------------LFC 309
            | |||::                    :|.:.:...:|.:                      :|.
  Fly   232 PEQSEHWRQEVASQVVQIEQQLAKGLPHNPALTLAQTTRQRTAAEMKTAYGSYVDVTRYLQLIFN 296

  Fly   310 DFYYVEL------------DKVCARHRKAVANYLAMKLLYRFDPKLKAPRYQRN--YCSVTLYQ- 359
            |..|::|            |.:....:..:|||...|.|...| ..:.|..||.  :| |.|.|
  Fly   297 DNLYMDLYETPEDYMSNLVDVIRETPKLQLANYTMWKALEALD-IARVPASQRADIWC-VQLAQQ 359

  Fly   360 ----SMRFLFNKLYMANNFSEAKRLE--MSEMVRELRKSLRKALEDADWLDAESRARALLKESRI 418
                .:..||::.|  |:......|:  .|::.|..|:.| :|.|...||..|:|.:|:.|...:
  Fly   360 FFPHQLESLFHRNY--NHMQMINELQSTWSDIKRVFREDL-QASERLLWLTLETRQKAITKLEAL 421

  Fly   419 QPRIGSFQDDALSDRIIREINSLKVIEDRY------------------------AETNIN-LQHL 458
            :....:..|    :::||:::.|.:..||:                        ||..:: |.|.
  Fly   422 KLHFRTHDD----NKLIRQMHGLILNMDRFYPNLVSVLQWKTQRGLAKLMTEPVAEDEVHKLPHY 482

  Fly   459 VVQINRFSSRHFQELTNDTKPQKILTGLQVGAGYYTPDNSINVMAGVVEPPIYQRHLPISLKFGT 523
            .:|.||.              |..:|.||               |.....|.|    |..||:.|
  Fly   483 EIQKNRI--------------QVPITFLQ---------------ARFFWDPAY----PNGLKYAT 514

  Fly   524 LGFIVGHELIHGFDTTSSYFDGNGHMESLLSEISQQALEDRAECYMDYYGKYQVPEISRRVNGKT 588
            ||.::..:::||||.....:|..|:..:.....|:.:...|.:|:.:.|..: |....:.|..|.
  Fly   515 LGVLLARQMLHGFDGVGRRYDAYGYKNNWWDHTSESSYSRRTQCFQEQYAIF-VEYKGKPVQDKD 578

  Fly   589 TLDENIADNSGLRQALTAYRSHRQQLLEHPGQERI---SDAMPGLDLTPEQLFFLGFAQLFCSHY 650
            .|...:|||..|..|..||    ||.|::..:..:   .:.:|.||....|:|:||:|||:|:.|
  Fly   579 LLRRIVADNGALDIAYRAY----QQWLKNAAETPVIYQRERLPLLDHDHNQIFYLGYAQLYCTDY 639

  Fly   651 EEEHYWKGLSDVHTFD----QFRVLGVLSNSEDFFHAYNCS 687
            .|        .|..||    |.||...||||:.|.:||.||
  Fly   640 PE--------TVERFDELPEQLRVNTALSNSQQFANAYGCS 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl12	NP_649924.1	M13	68..700	CDD:341056	164/731 (22%)
Nepl15	NP_651098.2	M13	56..684	CDD:341056	164/729 (22%)