Protein Alignment Nepl12 and Nepl14

DIOPT Version :9

• Sequence 1: NP_649924.1
• Gene: Nepl12 / 41172
• FlyBaseID: FBgn0037727
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Alignment Length: 729
• Identity: 160/729 - (21%)
• Similarity: 280/729 - (38%)
• Gaps: 173/729 - (23%)

  Fly    57 AEFMKSYMNQSVEPCENFYEYACGNYRNV---------KPDRYSPGSRSNLGDVTYTLIDITEQL 112
            |:.|.|::|:|::||.:||.|||||:::.         :.||              .|:.:.|:.
  Fly    49 AQDMGSHVNKSIDPCVDFYAYACGNWKSTLTPQQQLQQQTDR--------------ELLLLVEEA 99

  Fly   113 LGRMDLAEALNVSSELAVAQRFYNACLGANLHPFNAADPAYLSLIRSIGGFPAVDGDAWKA--SN 175
            :.|.|       |..:..|:..:.:|:.|..|............|...||||||.|..|..  .:
  Fly   100 VRRED-------SVIVRQAKELFKSCVSAQAHQSQQQQHFLSEFINQNGGFPAVPGSQWAVHHHD 157

  Fly   176 FNWINMSAHL-ANYGANGLIRETLQLRYPF-----------EPYTKLPELGFDHIIVHEENISRN 228
            :||:::...| ..||.:.||  .|::.|.:           ||.|.:|          .|..:||
  Fly   158 YNWLSVLGGLRLRYGMDILI--GLRVGYNYGNVNENSLYLSEPSTLIP----------TELCTRN 210

  Fly   229 TT----RAFRLNEERMHGYLRAF-GLPEDRIREAIAGVFAF---------------WRDALEIPP 273
            .:    ..:...|.|:...|::: .|..|......|.:.:|               | ||.|
  Fly   211 RSDIRDSIYEPLEHRVASELKSWLALGHDESARLAADILSFEHELCGGMKGGSFESW-DAEE--- 271

  Fly   274 QCEVFDPYRIK--RVFPQS-----EYYYNISW-SGLHSTNKLFCDFYYVELDKVCARHR-KAVAN 329
            |..:.: |..|  |.|..|     :.|...|: ..::....:....|:.:|.:..:.|. ..|||
  Fly   272 QLYLAN-YTRKTLREFSNSIELDLDSYVRASFGQDIYKPVYMAAPEYFRQLKRTVSAHNISLVAN 335

  Fly   330 YLAMKLLYRFD-PKLKAPRYQRNYCSVTLYQSMRFLFNKLYMANNFSEAKRLEMSEMVRELRKSL 393
            |:..:.:...: |....|:.::..|.....:.:.....:||.....:|..|:::..:...|:.:|
  Fly   336 YIMYRAVSALNFPLDDRPQLRKRECLERTKELLPTALGELYARQFGTEDGRIDLDNLYDTLKTAL 400

  Fly   394 RKALEDADWLDAESRARALLKESRIQPRIGSFQDDALSDRIIREINSLKVIEDRYAETNI----- 453
            |::| .|:||...::            |:|.           .::.:||:....|....|
  Fly   401 RQSL-GAEWLVEGTQ------------RVGQ-----------EKLRNLKLQMPTYERPVILKLQL 441

  Fly   454 -------NLQHL--VVQINRFSSRHFQE-LTNDTKPQKILTGLQVGAGYYTPDNSINVMAGVVEP 508
                   ||:.|  |||..| ::|.|:| |...|.|   :...:...........:::...:::|
  Fly   442 ERGNYWQNLRQLLGVVQSQR-NNRLFEEFLPAPTDP---VEAYEARVRLRPVQRRLDMGLALLQP 502

  Fly   509 PIYQRHLPISLKFGTLGFIVGHELIHGFD--------TTSSYFDGNGHMESLLSEISQQALEDRA 565
            |.|......::::.|||..:..:|:..||        .....:||....:..:          |:
  Fly   503 PAYDPRYGHAIRYATLGVQLAQQLVMAFDDPHWSVGLLERDNWDGQTAWQYHI----------RS 557

  Fly   566 ECYMDYYGKYQVPEISRRVNGKTTLDENIADNSGLRQALTAYRSHRQQLLEHPGQE---RISDAM 627
            .|:......|..|.:|     .||  :.|.|::.:..|..||.:...  .:.|..:   ...:.:
  Fly   558 NCFARQVDNYLRPNVS-----ATT--QLITDSAAINVAFRAYLTWLG--FQEPNNDFTKLTKETL 613

  Fly   628 PGLDLTPEQLFFLGFAQLFCSHYE---------EEHYWKGLSDVHTFDQFRVLGVLSNSEDFFHA 683
            |.|:.:...||||.:||..||..|         .|.|.......||:.:..|.|.|.||.:|...
  Fly   614 PDLNYSNTALFFLAYAQEHCSLEEARPRDEQGTPEGYLYSARQNHTWTRLLVNGPLRNSVEFASE 678

  Fly   684 YNCSVGSGMRPGAK 697
            :.|.:||.|.|.:|
  Fly   679 FRCPIGSPMNPASK 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl12	NP_649924.1	M13	68..700	CDD:189000	155/718 (22%)
Nepl14	NP_651097.1	M13	60..693	CDD:189000	155/718 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454950
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850