Protein Alignment Nepl12 and Nepl13

DIOPT Version :9

• Sequence 1: NP_649924.1
• Gene: Nepl12 / 41172
• FlyBaseID: FBgn0037727
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 790
• Identity: 182/790 - (23%)
• Similarity: 303/790 - (38%)
• Gaps: 164/790 - (20%)

  Fly     8 LISLMLLWVIVAAVLTDCEARSLVDRSENSDSNGSSTNRSAAEYQLQEYAEFMKSYMNQSVEPCE 72
            |:.|:||:.|....:|  |||.  :.......:|:..:....:...|:.|..::.|||.|.:||.
  Fly    12 LLELLLLFEIQLCDVT--EARQ--NHMNRMQMSGNFPDSREEQLVRQKIATDVQKYMNLSADPCT 72

  Fly    73 NFYEYACGNY-----RNVKPDRYSPGSRSNLGDVTYTLIDITEQLLGRMDLAEALNVSSELAV-- 130
            :|:|||||.:     |.::||..|...:.....::..|..:..|.|.........:.:|...|
  Fly    73 DFFEYACGQWGRYHKRQLRPDELSTAQQLMETKISEQLQQLLTQPLPPQHHPNGYSGASMTNVRK 137

  Fly   131 AQRFYNACLGANLHPFNAADPA--YLSLIRSIGGFPAVDGDAWKASNFNWINMSAHL-ANYGANG 192
            .:.||.:|:....   ||::..  .:.:::..||...|....|: .|..|:.....| .|||.:.
  Fly   138 VRAFYESCVAVEA---NASERRRFLMKILKDNGGLRNVPNSNWQ-HNRQWVQTLGELRRNYGLDI 198

  Fly   193 LIRETLQLR---------YPFEPYTKLPELGFDHIIVHEENISRNTTRAFRLNEERMHGYLRAFG 248
            |:...:.|.         |..||  ||       .|:..|:.:...||..::.:|       .:.
  Fly   199 LLGLEIDLNLQTMKGNTIYFGEP--KL-------TIIPAEHCNALATRGAQVRDE-------VYE 247

  Fly   249 LPEDRIREAI----------AGVFA--FWRDALEIPPQCEVFDPYRIKRVFP---QSEYYYNISW 298
            |.:.::.|.:          |..||  ..|...|:..|....|..:.:..||   |::.|...|.
  Fly   248 LVQQQVTENLRDWFGMDTGEAARFAGDIIRFEFELCKQMGEQDIQKPEEEFPPAIQAQIYGARSR 312

  Fly   299 SGLHSTNKLFCDFYYVELDKVCARHRKAVANYLAMKLL--------YRFDPKLKAPRYQRNYCSV 355
            :|.....:........||       ...:.|:|..|:|        |.....|::|.|.::...
  Fly   313 TGQERLRRQKGGMTLTEL-------TSEMGNHLDFKMLVEVILESQYPSQVYLRSPEYVKHVVR- 369

  Fly   356 TLYQSMRFLFNK--LYMA-NNFSEAKRLEMSEMVRE----------------------------- 388
            |:..:.|.....  ||:| |..::......|:..|:
  Fly   370 TVKANNRITVGGYILYVALNELNQPPEEAPSQRARQCVQVTQRLFPQVLGEMFQRHVQRDNAKHD 434

  Fly   389 ---LRKSLRKALED---ADWLDAESRARALLKESRIQPRIGSFQDDALSDRIIREINSLKVIEDR 447
               :...:.||||:   .:|:|...|..|..:.|:.:..:..:|...|:|.      ..:..||.
  Fly   435 LDAVFNDVIKALEEQFHVEWMDENDRRAARTRLSQYRVSLPDYQSLDLTDL------QFQKSEDY 493

  Fly   448 YAETNINLQHLVVQINRFSSRHFQELTNDTKPQKI--LTGLQVGAGYYTPDNSINVMAGVVEPPI 510
            :....|.|::.       |.:.|:.|..:...|..  |...:|.|........:.|..|:::.|.
  Fly   494 WRRLEIALKYR-------SHQQFEALRGNDFGQDADGLDAFEVRAALSPRQQMVLVGWGLLQAPY 551

  Fly   511 YQRHLPISLKFGTLGFIVGHELIHGFDTTSSYFDG-NGHMESLL--SEISQQALEDRAECYMDYY 572
            |..:.|.|||:..||..:...|:..||.     :| |.|.::..  :|::.....:.:||....|
  Fly   552 YNYYYPKSLKYALLGHRLASALVQAFDD-----EGWNNHPQATAQWNEVTMSGYRNASECQRAQY 611

  Fly   573 GKYQVPEISRRVNGKTTLDENIADNSGLRQALTAYRSHRQQLLEHP-----GQERISDAMPGLDL 632
            ..|...|.....|. |.|.|.|||.|||..|..||.:..:| .:|.     .:|.:|:    |:.
  Fly   612 SSYLYNEPGEFRNA-TRLREIIADGSGLNLAFNAYLAWLEQ-QDHKLRPLLAKETLSE----LNF 670

  Fly   633 TPEQLFFLGFAQLFCSHYEEEHYW-KGLSDV---------HTFDQFRVLGVLSNSEDFFHAYNCS 687
            |..||||:.|||..|        | |...|.         ||.:::.|.|.||||.:|...:.|:
  Fly   671 TNTQLFFIYFAQTRC--------WAKDNQDAILDSMPLMQHTPERWDVNGPLSNSAEFGREFGCA 727

  Fly   688 VGSGMRPGAK 697
            :|:.|..|.|
  Fly   728 LGTPMNSGDK 737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl12	NP_649924.1	M13	68..700	CDD:189000	166/730 (23%)
Nepl13	NP_651096.1	PepO	63..732	CDD:226118	167/728 (23%)
		M13	68..738	CDD:189000	166/730 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454942
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850