Protein Alignment Nepl12 and Nepl8

DIOPT Version :9

• Sequence 1: NP_649924.1
• Gene: Nepl12 / 41172
• FlyBaseID: FBgn0037727
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Alignment Length: 722
• Identity: 156/722 - (21%)
• Similarity: 247/722 - (34%)
• Gaps: 210/722 - (29%)

  Fly    62 SYMNQSVEPCENFYEYACGNYRNVKPDRYSPGSRSNLGDVTYTLIDITE-----------QLLGR 115
            |::::...||||:|.:|||.|              |:..:..|..||.:           :|:..
  Fly    26 SHVDKEANPCENYYNHACGQY--------------NMRHIDDTFFDIIQMLDHQVNQNLVKLMDE 76

  Fly   116 MDLAEAL---NVSSELAVAQRFYNACLGANLHPFNAAD-PAYLSLIRSIGG--FPAV--DGDAWK 172
            ::::..|   ||||......|:|.:|.||   |.|... ..||.:|....|  :|..  ||.:|.
  Fly    77 LEMSSQLPDFNVSSVDGKVLRYYLSCRGA---PRNMDSLSQYLKVISPGEGLTWPQFIPDGSSWP 138

  Fly   173 ASNFNWINMSAHLANYGANGLI-------------RETLQLRYP-FEPYTKLPE-----LGFDHI 218
            ..||.|:...|||..||...:.             ...::|..| |...::||.     |...:|
  Fly   139 QENFKWLKALAHLHRYGLTNVFFNLEVVSNPRNASEYMVELNTPTFGEESQLPNSFIEILSVLYI 203

  Fly   219 IVHEENISRNTTRAFRLNEERMHGYLRAFGLPEDRIREAIAGVFAF-------WRDALEI----- 271
            |....:......|..|..|.    .|:....|.|.:......:..|       |:...||
  Fly   204 IKVPSSEIITLARKMRTLEL----LLKTMINPIDTLNNRYISIRDFQMETGHNWQRFFEILIGSS 264

  Fly   272 -PPQCEVFDPYRIKRVFPQSEYYYNISWSGLHSTNKLFCDFYYVE-----LDKVCARHRKAVANY 330
             .|:.:|                             |..:|.|..     :||..||   .||:|
  Fly   265 AAPELQV-----------------------------LVRNFRYFTALKELMDKQDAR---LVASY 297

  Fly   331 LAMKL-LYRFDPKLKAPRYQRNYCSVTLYQSMRFLFNKLYMANNFSE----AKRLEMSEMVRELR 390
            :..:. ::..|..:..  .:...|...:.::|....|.||....|.:    |..||:.::..:||
  Fly   298 IMTRFAIFLLDETMGG--RESTECVSQVRRNMNLAANMLYKERFFEDSTFSANILEIKDIFEKLR 360

  Fly   391 KSLRKALEDADWLDAES--------RARA-------LLKESRIQPRIGSFQDDALSDRIIREINS 440
            ......: |.:.|:..:        :|.|       |.|...::..||.:..|
  Fly   361 HQFLLQV-DQNHLELTALQMKFFVRKAEAIEINVVNLPKTDDLRHFIGQYYQD------------ 412

  Fly   441 LKVIEDRYAETNINLQHLVVQINRFSSRHFQELTNDTKPQKILTGLQVGAGYYTPDNSINVMAGV 505
               ::....|.:.:.:||.|...|......|.....::.|.|||.....|....|.
  Fly   413 ---LQFPTGELDYHQEHLKVLQFRTQKMLAQSSKGHSEEQNILTYRSQAAPLPPPQ--------- 465

  Fly   506 VEPPIYQRHLPISLKFGTLGFIVGHELIHGFDTTSSYFDGNGHMESLLSEISQQALEDRAECYMD 570
               |.:|.......|:..:|:|:.|.||..|.|.......:|:.:|..|    ...|:...|
  Fly   466 ---PFFQLESEDVFKYSLMGYIMAHHLISAFATEGITIGSDGNDQSFRS----HRFEEAVSC--- 520

  Fly   571 YYGKYQVPEISRRVNGKTTLDENIADNSGLRQALTAYRSHRQQLLEHPGQERISDAMPGLDLT-- 633
                     :||   ....:||::.|.:||..|...|             .:::.....||.|
  Fly   521 ---------LSR---NSENIDESMGDIAGLELAYFTY-------------AKMAKNRNRLDFTHL 560

  Fly   634 -PEQLFFLGFAQLFCSHYEEEHYWKGLSDV---HTFDQFRVLGVLSNSEDFFHAYNCSVGSGMRP 694
             |||:|||...|.||          |.||:   :..||.|:...:...|.|..|:.|...   :|
  Fly   561 PPEQIFFLNVGQFFC----------GNSDMLVQYKEDQVRLQRAIEGFEPFDKAFGCYRN---KP 612

  Fly   695 GAKTCRL 701
            ..:.|||
  Fly   613 KHEKCRL 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl12	NP_649924.1	M13	68..700	CDD:189000	152/713 (21%)
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	152/713 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454894
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840