Protein Alignment Nepl12 and Nepl6

DIOPT Version :10

• Sequence 1: NP_649924.1
• Gene: Nepl12 / 41172
• FlyBaseID: FBgn0037727
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 766
• Identity: 162/766 - (21%)
• Similarity: 276/766 - (36%)
• Gaps: 188/766 - (24%)

  Fly    14 LWVIVAA-VLTDCEARSLVDRSENSDSNGSSTNRSAAEYQLQEYAEFMKSYMNQSVEPCENFYEY 77
            :|:|... ::..|.|.:  .::..:|.|....|.             :.||:.:....|..:::|
  Fly     1 MWLIACLFIVPICAAPT--TQNVEADPNSRLMNN-------------ILSYVAEDSSACGTYFQY 50

  Fly    78 ACGNYR-NVKPDRYSPGSRSNLGDVTYTLIDITEQLLGRMDLAEALNVSSELAVAQRFYNACLGA 141
            |||.|. ..:.|.::...:.....|...|:.:..:|..|.. :...|.||..|....||..|..|
  Fly    51 ACGKYAVRHRDDPFTEIIQMLDHKVNGNLVQLMHELHQRSQ-SPGFNESSVEAKVLHFYRTCREA 114

  Fly   142 NLHPFNAADPAYLSLIRSIGGFPAVD----------GDAWKASNFNWINMSAHLANYGANGLIRE 196
              .|.......||.|.      |...          |:.|..:.|.|:....||..||...::..
  Fly   115 --PPSTRKMEHYLRLA------PPGQALTWPQFMPRGEPWPKAQFKWMKSLGHLYRYGFTNVLVN 171

  Fly   197 TLQLRYPFEPYTKLPELGFDHIIVHEENISRNTTRAFRL---------NEERMHGY------LRA 246
            .|.||                       .|.|:.| |||         :.:.:.|:      |:.
  Fly   172 VLVLR-----------------------SSENSNR-FRLDISMPSLEGDAQHLGGFLSTLATLQI 212

  Fly   247 FGLPED----------RIREAIAGVFAFWRDALEIPPQCEVFDPYRIKRVFPQSEYYYNISWSGL 301
            .|:|..          |:..||       |...|:....| .:.:.::    |.||....:|.|.
  Fly   213 IGVPTKSILPLVRKIRRLESAI-------RVLTEVDDDDE-SETWTLR----QWEYKTGYAWQGF 265

  Fly   302 ------HSTNKLFC-----DFYYVELDKVC-ARHRKAVANYLAMK-LLYRFDPKLKAPRYQRNYC 353
                  ||.:..:.     ..|:..|.::. :...:.||||:..: :||..|..:.:..:..  |
  Fly   266 VESIVGHSVSHHYVMQAQNAKYFTGLKRLMDSTDAEVVANYIMTRFVLYLIDDFIDSNEHID--C 328

  Fly   354 SVTLYQSMRFLFNKLYMANNFSEAKRLEMSEMVRELRKSLRKAL-----EDADWLDAESRARALL 413
            ...:.::|....|.||.......|...:.::.|.::.:.||:..     |:...|.:|..:....
  Fly   329 VTDMRRNMNLASNLLYKERFLDPATLQQYTQEVTKVFEQLRRQFLLQINENRLGLTSEQNSMVAT 393

  Fly   414 KESRIQPRIG---------SFQDDALSDRIIREINSLKVIEDRYAETNINL-----QHLVVQINR 464
            |...:...||         ||......|.:      ..:.:..||..::||     :..|:|:|:
  Fly   394 KAQHVVLNIGNLPRGRDHRSFVSRHYEDLV------FPLPDFDYAREHLNLLEFRTRKQVLQLNQ 452

  Fly   465 FSSRHFQELTNDTKPQKILTGLQVGAGYYTPDNSINVMAGVVEPPIYQRHLPISLKFGTLGFIVG 529
             |:....|....:.|:   |.:..|..|....|.|.|..|:::.|.:........|:..|||::.
  Fly   453 -SAPTPDEFFYLSDPK---TAMSSGPYYLMRLNIIVVPHGLLQEPFFAADSHDIFKYSLLGFVLA 513

  Fly   530 HELIHGFDTTSSYFDGNGHMESLLSEISQ--------QALEDRAECYMDYYGKYQVPEISRRVNG 586
            |||:|..||...|:|..|::..:..:||.        |.|...:..|
  Fly   514 HELMHSVDTVGLYYDRYGNIHEIGPQISSSPRFVAGLQCLNRNSTQY------------------ 560

  Fly   587 KTTLDENIADNSGLRQALTAYRSHRQQLLEHPGQERISDAMPGLDLTPEQLFFLGFAQLFCSHYE 651
               |||.|||.:||..|.:.|       .::..|..::|.   ..:.|:|:|||..||.||...:
  Fly   561 ---LDERIADIAGLDLAYSTY-------FQNSSQMSLTDF---TTIPPQQIFFLNLAQFFCGDGD 612

  Fly   652 EEHYWKGLSDVHTFDQFRVLGVLSNSEDFFHAYNCSVGSGMRPGAKTCRLW 702
            ..::..     |..|:.|:..:|:....|..|:.|...|..   .:.|:||
  Fly   613 PINFVG-----HDNDETRLQQMLNGFAPFHEAFGCPAKSNQ---PEKCQLW 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl12	NP_649924.1	M13	68..700	CDD:341056	150/707 (21%)
Nepl6	NP_609023.3	M13	47..653	CDD:341056	149/701 (21%)