Protein Alignment Nepl12 and goe

DIOPT Version :10

• Sequence 1: NP_649924.1
• Gene: Nepl12 / 41172
• FlyBaseID: FBgn0037727
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_573160.1
• Gene: goe / 32660
• FlyBaseID: FBgn0027528
• Length: 879
• Species: Drosophila melanogaster
• Alignment Length: 775
• Identity: 146/775 - (18%)
• Similarity: 233/775 - (30%)
• Gaps: 314/775 - (40%)

  Fly    63 YMNQSVEPCENFYEYACGNYRNVKPDRYSPGSRSNLGDVTYTLIDITEQLLGRMDLAEALNVSSE 127
            :.|.|..||...||:||||:            .|:..:..|.:|...|...      |..|...|
  Fly   178 WANTSKSPCHETYEWACGNF------------ASDYANHEYFVIKRGEWNY------ETYNEYQE 224

  Fly   128 LAVAQRF-------------------YNACLGANLHPFNAADPAYLSLIRSIGGFPAVDGDAWKA 173
            |....||                   |.:|...::...:.:|   |.|.|:|.   ||.|  |:|
  Fly   225 LNELNRFIAMLPNSQEGSVESTVSSLYRSCRETDVLDKSQSD---LLLKRAIN---AVYG--WQA 281

  Fly   174 SNFNWINMSAHLANYGANGLIRETLQLRYPFEPYTKLP-ELGF----DHIIVHEENISRNTTRAF 233
                 ...|..|.::....:: ..||.::...||.::. |.||    |::|..:|.
  Fly   282 -----FRDSNRLQSWEYKRVL-VVLQAKHGIFPYYRVTVENGFSNPHDYVITLDEG--------- 331

  Fly   234 RLNEERMHGYLRAFGLPE------DRIREAIAGVFAFWRDALEIPPQCEVFDPYRIKRVFPQSEY 292
                        ..|||:      |...|.:.|.....||
  Fly   332 ------------ELGLPDKYFYGNDADEEVVRGYKLLLRD------------------------- 359

  Fly   293 YYNISWSGLHSTNKLFCD--FYYVELDKVCARH---RKAVANYLAMKLLYRFDPKLKAPRYQRNY 352
             :.|:...:.....||.|  |:|   ::....|   .||.||....||:...|.|:|||
  Fly   360 -FAINMGIVSREADLFADDIFHY---ERRIVNHIEDAKADANRPINKLMRLADLKIKAP------ 414

  Fly   353 CSVTLYQSMRFLFNKLYMA----------------------------NNF--------------- 374
             |:.:.:|::.:|.|..:.                            |||
  Fly   415 -SLPILESLQAIFPKTKITEDTEVLVRDPEVMHALSVLLSTSDKKPINNFIVWSLARKMLPHLSK 478

  Fly   375 ------------------SEAKRLEMSEMVRE--------------------------------- 388
                              |..:.|..|::||:
  Fly   479 EYRTLAETFDHALYGRTASYPRWLICSKVVRDWLPFAVDALQQQPPRQQFETMTSKSRGLNKTQG 543

  Fly   389 -----------LRKSLRKALEDADWLDAESR--ARALLKESRIQPRIGSFQDDALSDRIIREINS 440
                       ||..|:.:||.|.||:..:|  .:..|.|.|:|        ..:.|.::::...
  Fly   544 NEELLKLMFFSLRNQLKDSLEQAKWLEPAARQFIQKKLNEMRLQ--------FGIPDEVLQQPTY 600

  Fly   441 LKVIEDRYAETNINLQHLVVQINRFSSRHFQ--------ELTNDTKPQKILTGLQVGAGYYTPD- 496
            |   ...|.|..:|        |.|...|.:        ::.....|..||.  .:.:..||.|
  Fly   601 L---AQYYNELILN--------NVFFVEHLEWIWTFRRSQMEKKLGPLAILD--VIVSEMYTRDN 652

  Fly   497 -------NSIN---VMAGVVEPPIYQRHLPISLKFGTLGFIVGHELIHGFDTTSSYFDGNGHMES 551
                   |.:|   |...::....|....|:::.|..:|..:...||..|.|....|:...
  Fly   653 PQAIAYSNKLNMLLVSKVLISSNYYDYRYPVAVNFARIGTDILEALIDNFSTFLLQFNTQS---- 713

  Fly   552 LLSEISQQALEDR-AECYMDYYGKYQVPEISRRVNGKTT-------------------------- 589
              ::||..|.|.| |:..::.....|.|.:...:|..::
  Fly   714 --TDISDAAPEIRYAQPDVNCLAAGQPPRLVHELNELSSNALKSFHVTLSAARTAARALSNFVNA 776

  Fly   590 LDENIA-DNSGLRQALTAYRSHRQQLLEHPGQERISDAMPGLDLTPEQLFFLGFAQLFCS 648
            :|...| ..||:.||.|.......:.|..||....::         .:||.|.:.|..||
  Fly   777 IDAGSAIQGSGIDQANTYEALGLTRRLRIPGLRSFNE---------NELFTLSYMQQHCS 827

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl12	NP_649924.1	M13	68..700	CDD:341056	144/770 (19%)
goe	NP_573160.1	GluZincin	184..>692	CDD:472708	113/617 (18%)