Protein Alignment Nepl12 and Nepl3

DIOPT Version :9

• Sequence 1: NP_649924.1
• Gene: Nepl12 / 41172
• FlyBaseID: FBgn0037727
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 781
• Identity: 160/781 - (20%)
• Similarity: 251/781 - (32%)
• Gaps: 265/781 - (33%)

  Fly    11 LMLLWVIVAAVLTDCEARSLVDRSENSDSNGSSTNRSAAEYQLQEYAEFMKSYMNQSVEPCENFY 75
            |.|.|:::....|.|.|...:                       |..:.|...|::.||||.|||
  Fly     8 LSLSWLLLLLCSTVCSANPNL-----------------------EIMKRMLDDMDEKVEPCHNFY 49

  Fly    76 EYACGNYRNVKPDRYSPGSRSNLGDVTYTLID-ITEQLLGRMDLAEALNVSSELAVAQRFYNACL 139
            .   .:.:|:|...:     :.:.|....|.| |..::..:....|.|         ||.|..|
  Fly    50 N---SSQKNLKWHAF-----ATVSDQFQLLFDGIENEVFEKHSFEEKL---------QRLYKIC- 96

  Fly   140 GANLHPFNAADPA---YLSLIRSIGGFPAVD---------GDAWKASNFNWINMSAHLANYGANG 192
                  .....|:   |..|::     |..|         |..|....|.|:...|.|..||.|.
  Fly    97 ------STMERPSLLRYFELVK-----PGEDLNWPFLTPRGGKWPKEKFQWMEALARLRRYGFND 150

  Fly   193 L-----IRETLQLRYPFEPYTKLPELGFDHIIVHEENISRNTTRAFRLNEERMHGYLRAFGLP-- 250
            :     ||:        :|.:...:    .|:|.|:...    ..||..|.     |:..|||
  Fly   151 IMFGMSIRQ--------DPNSDSGQ----PIVVFEKKYD----SLFRFIES-----LQNIGLPPK 194

  Fly   251 --------EDRIREAIAGVFAFWRDALEIPPQCEVFDPYRIKRV-FPQSEYYYNISWSGLHSTNK 306
                    ::.|:|.......|...|.:..|         :||: ..|.|.|      |:..|..
  Fly   195 LAKEIAPLDNAIQEMYKSDMKFEHYARDAAP---------VKRISLGQLEIY------GVSLTKY 244

  Fly   307 LFCDF---------------YYVE--LDKVCARHRKAVANYLAMK----LLYRFDPKLKAPRYQR 350
            |...|               ||:.  .:.:.|...:.|||||..:    :::.|   :|    ..
  Fly   245 LEIVFGRPFSPDFVVHVENLYYLRGLQNLMTAVPSQVVANYLTARFSFYIMFTF---MK----HG 302

  Fly   351 NYCSVTLYQSMRFLFNKLYMANNFSEAKRLEMSEMVRELRKSLRKALE---DADWLDAESRARAL 412
            :.|..|:.|||.|..|.|:........|.........::..::|:.|.   :.:.|.......:|
  Fly   303 DSCVTTMRQSMEFASNLLFEERILGRKKLRSYQNQAGKIFDAIRQQLNIRLERNVLKLPPAEISL 367

  Fly   413 L--KESRIQPRIGSFQDDALSDRII----REIN----------SLKVIEDRYAETNINLQHLVVQ 461
            |  |.:.:...||:....|...|.:    :|:.          .|||:|.|   |...|. |:.|
  Fly   368 LQKKLNGLSLSIGNLPGKAGHRRFVTRYYKELEFADDEELATAHLKVLEHR---TRAELS-LLDQ 428

  Fly   462 INRFSSR----HFQELTN---DTKPQKILTGLQVGAGYYTPDNSINVMAGVVEPPIYQRHLPISL 519
            .| |..|    |...::|   :|             .|....|:|.|....:....:........
  Fly   429 PN-FKDRRYMLHSYPISNFFFET-------------AYEENGNTIYVAYDFLADASFDPDSHDIF 479

  Fly   520 KFGTLGFIVGHELIHGFDTTSSYFDGNGHMESLLSEISQQALEDRAECYMDYYGKYQVPEISRRV 584
            |...||...|.|::..||    .|:...|..::|     |..:|
  Fly   480 KVTPLGIRFGLEMLKSFD----LFNCKHHKVNML-----QLFDD--------------------- 514

  Fly   585 NGKTTL-DENIA----DNSGLRQALTAYRSHRQQLLE--HPGQE-------RISDAMPGL-DLTP 634
            |..||. ||.::    ||         ..|.|.|.|.  |...|       :.|...|.. .::.
  Fly   515 NQITTAGDECVSAWTQDN---------LLSQRDQYLVVLHLVHEAYFAEGSKFSQRQPNFTTMSL 570

  Fly   635 EQLFFLGFAQLFCSHYEEEHYW-----KGLSDVHTFDQFRVLGVLSNSEDFFHAYNCSVGSGMRP 694
            .:|||..|.|   |.:.:..|:     :|.|.:::..:..|         |...:||     :.|
  Fly   571 RELFFFRFGQ---SSFGQTLYFGSDFVEGGSPINSLTRLPV---------FVRTFNC-----LAP 618

  Fly   695 G 695
            |
  Fly   619 G 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl12	NP_649924.1	M13	68..700	CDD:189000	151/724 (21%)
Nepl3	NP_608904.1	GluZincin	42..581	CDD:301352	141/670 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454984
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740