DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nepl12 and nep-15

DIOPT Version :9

Sequence 1:	NP_649924.1	Gene:	Nepl12 / 41172	FlyBaseID:	FBgn0037727	Length:	702	Species:	Drosophila melanogaster
Sequence 2:	NP_001257056.2	Gene:	nep-15 / 185513	WormBaseID:	WBGene00018227	Length:	267	Species:	Caenorhabditis elegans

Alignment Length:	229	Identity:	64/229 - (27%)
Similarity:	89/229 - (38%)	Gaps:	65/229 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   496 DNSINVMAGVVEPPIYQ----------RHLPISLKFGTLGFIVGHELIHGFDTTSS------YFD 544
            |:..|:||..::...|:          .|  |:|..|..||.||||:.|.|....|      ||.
Worm    50 DSPRNLMATALKNLTYELRQKQADLFWNH--ITLVLGFTGFSVGHEIGHSFFANHSGTDILPYFS 112

  Fly   545 GN------GHMESLLSEISQQALEDRAECYMDYYGKYQVPEISRRVNGKTTLDENIADNSGLRQA 603
            .|      ....|..:|..:::...|.|                      .||:|.||..||:
Worm   113 ENVEKCVQNQFNSTCNEYKEESCVTRNE----------------------MLDDNGADIFGLQ-- 153

  Fly   604 LTAYRSHRQQLLEHPGQERISDAMPGLDLTPEQLFFLGFAQLFCS------HYEEEHYWKGLSDV 662
             .||:     |:|.....|:.:.:..|::|.|||||..||..|||      ..|||    |..|.
Worm   154 -LAYK-----LMEKYLSGRLEERIERLNVTQEQLFFYSFANQFCSGSLSKVFIEEE----GDYDP 208

  Fly   663 HTFDQFRVLGVLSNSEDFFHAYNCSVGSGMRPGA 696
            |:.:..|| ..::....|..|:||...|.|...|
Worm   209 HSVNNVRV-NAVAQHPGFRKAFNCPDNSRMMKSA 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nepl12	NP_649924.1	M13	68..700	CDD:189000	64/229 (28%)
nep-15	NP_001257056.2	GluZincin	<87..237	CDD:387391	53/184 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910