Protein Alignment Nepl12 and nep-4

DIOPT Version :10

• Sequence 1: NP_649924.1
• Gene: Nepl12 / 41172
• FlyBaseID: FBgn0037727
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_509156.2
• Gene: nep-4 / 183746
• WormBaseID: WBGene00016896
• Length: 437
• Species: Caenorhabditis elegans
• Alignment Length: 435
• Identity: 100/435 - (22%)
• Similarity: 153/435 - (35%)
• Gaps: 114/435 - (26%)

  Fly   294 YNISWSGLHSTNKLFCDFYYVELDKVCARHRKAVANYLAMKLLYRFDPKLKAPRYQRNYCSVTLY 358
            |||::...|.....||...::..|                 ..|||          .||  ||.|
 Worm    82 YNINFRRSHICCHFFCKLLFIYYD-----------------YQYRF----------INY--VTFY 117

  Fly   359 QSMRFLFNKLY--MANNFSEAKRLEMSEMVRELRKSLRKALEDADWLDAESRARALLKESRIQPR 421
            ..|   ...||  :..|.::... |:.:|:.::.:.....||...|:
 Worm   118 DGM---LQPLYYHVEANVTDGIN-EIHQMMEDMVELGNIWLEKTPWV------------------ 160

  Fly   422 IGSFQDDALSDRIIREINSLK--VIEDRYAETNINLQHLVVQ--INRFSSRHFQELTNDT----- 477
                .::.|::.:....|::|  |...:|.....||...:..  :|..|  .|:.:.|:|
 Worm   161 ----INNNLTEEMKNITNAIKMPVSLTKYTNFIYNLLSPIETDFLNCVS--EFEGIQNNTLFCLF 219

  Fly   478 KPQKILTGLQVGAGYYTPDNSINVMAGVVEPPIY-----QRHLPI----SLKFGTLGFIVGHELI 533
            ...||.  ::....|:..||..|     .|..||     ..|...    :.|.|..|..||||:.
 Worm   220 YSAKIF--VRTRGSYFIDDNGYN-----AEGTIYFGFPNYYHTTYGNWRASKLGYTGTRVGHEIG 277

  Fly   534 HGFDTTSSYFDGNGHMESLLSEISQQALEDRAECYMDYY----GKYQVPEISRRVN-GKTTLDEN 593
            |.|...|...||       |...|:.| ||   |..:.|    .:|...|:....| ...|.|:|
 Worm   278 HTFIEHSINPDG-------LPYFSKPA-ED---CVQNQYLKTCNEYYEGEVPDACNTSDYTFDDN 331

  Fly   594 IADNSGLRQALTAYRSHRQQLLEHPGQERISDAMPGLDLTPEQLFFLGFAQLFCSHYEEEHYWKG 658
            .||..||:.|..        :||....:::.:...||.:|.|||.|..||..||...:.    ..
 Worm   332 GADVFGLQLAYA--------ILERDLSDQLREQADGLKITNEQLLFYSFAYRFCRGSKS----NT 384

  Fly   659 LSDVHTFDQFRVLGVLSNSEDFFHAYNCSVGSGMRPGA-KTCRLW 702
            ....|:....|: ..::....|..|:||:..|.|...| |.|.::
 Worm   385 TDGSHSHHNVRI-NAVAQMPGFQQAFNCASDSRMMKSATKQCVIY 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl12	NP_649924.1	M13	68..700	CDD:341056	99/431 (23%)
nep-4	NP_509156.2	GluZincin	250..425	CDD:472708	54/198 (27%)