Protein Alignment Nepl12 and nep-11

DIOPT Version :9

• Sequence 1: NP_649924.1
• Gene: Nepl12 / 41172
• FlyBaseID: FBgn0037727
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_494538.1
• Gene: nep-11 / 173685
• WormBaseID: WBGene00017557
• Length: 848
• Species: Caenorhabditis elegans
• Alignment Length: 727
• Identity: 177/727 - (24%)
• Similarity: 311/727 - (42%)
• Gaps: 143/727 - (19%)

  Fly    64 MNQSVEPCENFYEYACGNYRNVKPDRYSPGSRSNLGDVTYTLIDITEQLLGRMDLAEALNVSSEL 128
            ||.||:||::|:|:|||.:.:..|   .|......|...|....:.:||...:: .|.:..|..:
 Worm   177 MNTSVDPCDDFFEFACGQWNDQHP---IPDDMYGFGTFAYAREQVRQQLRVLLE-QEVVTESESI 237

  Fly   129 AVAQRFYNACLGANLHPFNAADPAYLSLIRSIGGFPAVDGDAWKASNFNWINMSAHLAN----YG 189
            .:|:..|.:|:...........|.:.:| ..:|.:|.:. :.|..:.||:.::   |.|    ||
 Worm   238 NMARATYRSCMNKTQLDELMTGPLFETL-TELGEWPLLQ-ENWDKTKFNFTSL---LVNSRRDYG 297

  Fly   190 ANGLIRETLQLRYPFEPYTKLPELGFDHIIVHEENISRNT-------------TRAFRLNEERMH 241
            .:..          |:.|          |....:|.||||             ||.:.||.....
 Worm   298 VDVF----------FQLY----------IYADSKNTSRNTLFIDQSTLALGRGTRDYYLNTTLFS 342

  Fly   242 GYLRAF-----------------GLPEDRIREAIAGVFAF-------------WRDALEIPPQCE 276
            .::.|:                 ...|..:...|..:..|             .|:...:..:.:
 Worm   343 SHMTAYRKYLRQIAHLLKTDGNLTRSESEMNADIEKIIDFEIELAKIIVAEDERRNNTRLYNKRQ 407

  Fly   277 VFDPYRIKRVFPQSE---YYYNISWSGL-----HSTNKLFCDFYYVE-----LDKVCARHRKAVA 328
            :.|.|.:   .||.:   ::.:|:.|.|     :.|..:.|:..|::     ::|...   ..:.
 Worm   408 IQDLYNL---LPQVDWVPFFQSIAPSDLTHLFHNETEIIICEIEYLQHVSELIEKTDV---GLLT 466

  Fly   329 NYLAMKLLY--------RFD------------PKLKAPRYQRNYCSVTLYQSMRFLFNKLYMANN 373
            ||:..:::.        ||:            .:...||::.  |:......:......:|:..:
 Worm   467 NYVLWRVVQSNVRYLDERFEDIKQDFLKVMTGQQQSPPRWKD--CAQVPSTVLPLAAGAIYVQAH 529

  Fly   374 FSEAKRLEMSEMVRELRKSLRKALEDADWLDAESRARALLKESRIQPRIGSFQDDALSDRIIREI 438
            |.|:.:.|...|:..||.|....:...||:|.|::|.|:.|.:.:...|| :.|         ..
 Worm   530 FQESDKHEALRMIMHLRNSFADLVRQNDWMDEETKAVAIEKANSMINNIG-YPD---------VT 584

  Fly   439 NSLKVIEDRYAETNINLQHLVVQINRFS-----SRHFQELTNDTKPQKILTGLQVGAGYYTPD-N 497
            |.|..::.:|...:|:.......|.:.|     ||.||:||......:......|...:|:|: |
 Worm   585 NDLPKLDKQYLGLSISDSDTYYYIMKKSVVWMQSREFQKLTKPFDKHEFDISPAVVNAFYSPEKN 649

  Fly   498 SINVMAGVVEPPIYQRHLPISLKFGTLGFIVGHELIHGFDTTSSYFDGNGHMESLLSEISQQALE 562
            :|...||:::||.:....|.::.:|.:|.::|||:.||||...|.:|.:|::.:..||.|..:.:
 Worm   650 AITFPAGILQPPFFSGTFPKAVNYGAIGAVIGHEITHGFDDQGSQYDKDGNLHNWWSESSLNSFD 714

  Fly   563 DRAECYMDYYGKYQVPEISRRVNGKTTLDENIADNSGLRQALTAYRSHRQQLLEHPGQERISDAM 627
            .|..|.::.||.|.||:.:.|||||.|..||||||.|:::|..||:.:..:..|.|       .:
 Worm   715 TRRRCIVEQYGNYTVPKTNFRVNGKLTQGENIADNGGVKEAFQAYQKYVTENGEEP-------RL 772

  Fly   628 PGL-DLTPEQLFFLGFAQLFCSHYEEEHYWKG-LSDVHTFDQFRVLGVLSNSEDFFHAYNCSVGS 690
            ||| ..|.||:||:.:|..:|...:|....:. |:|.|:.:.|||:|||||.:.|...|.|...:
 Worm   773 PGLQQYTNEQIFFVSYAHFWCGKKKEAAAMQQVLTDEHSPEVFRVIGVLSNMQAFADVYKCPRNA 837

  Fly   691 GMRPGAKTCRLW 702
            .:.|..| |.:|
 Worm   838 PVNPDHK-CIVW 848

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl12	NP_649924.1	M13	68..700	CDD:189000	172/719 (24%)
nep-11	NP_494538.1	PepO	174..848	CDD:226118	176/725 (24%)
		M13	181..845	CDD:189000	172/718 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020