DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9492 and dhc1

DIOPT Version :9

Sequence 1:	NP_001287256.1	Gene:	CG9492 / 41171	FlyBaseID:	FBgn0037726	Length:	4724	Species:	Drosophila melanogaster
Sequence 2:	NP_001342921.1	Gene:	dhc1 / 3361400	PomBaseID:	SPAC1093.06c	Length:	4196	Species:	Schizosaccharomyces pombe

Alignment Length:	4527	Identity:	991/4527 - (21%)
Similarity:	1803/4527 - (39%)	Gaps:	986/4527 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   342 KEVQFTLHCLFLAGSRIIKQWKETDRKITFCYNEARDNSKFIQAMETCCHSLYLDDPVSMKESIL 406
            ||::.|  |         :::.:.:|..||...|.:::...:|.     |.|.|......:|:.|
pombe   184 KELELT--C---------QKFADFERSFTFFCREYQNSDTILQH-----HPLILSTIKHAEENNL 232

  Fly   407 SLLQTVRL----IYSVSQFYNTSERTSALMVKITNQMIETCKSYITCRCKE--TIWSQDRNVIRT 465
            .|  :|||    :.|.|:||.:......:.:|.|..:|:.....|:....|  ..|
pombe   233 DL--SVRLLPSKVLSDSEFYKSLSNLVNVWLKTTRSLIKLFHDQISKTALEEFNFW--------- 286

  Fly   466 KLSNCIKLNHIYHETYYTVREQPFLPNQTPFGFSENFVFGK-FDT------------FCERLSKI 517
                     ..|:.:...:.:|  |.::......:...||| |.|            |.:::.||
pombe   287 ---------QFYYRSLSRLNDQ--LHSRPVLFVLDILAFGKRFHTIASFNSETNIQCFVDKVGKI 340

  Fly   518 ISMFNLIDDYNHLFERRLEGLLLGEALEDASNHFEEAKKEV---TSRKYDYLDHRNSDF------ 573
            .::|..|.....|....||.|.|..||  ..:.|.:..:..   .:|..|:::....|.
pombe   341 DALFKEISLDIFLSSSTLESLQLSAAL--LYSTFSKKWRNTGYPETRVLDFINFITEDLLKLISR 403

  Fly   574 -----------NIDFERFIHKTNSLKDTIATLIEKDFDTVWETPQCIRFLVRFEKVSEKIPLTRM 627
                       |:||.   |:|....|.::.              |...|..|.::|..:   :.
pombe   404 LLPALGALSLSNVDFS---HRTAVSSDILSL--------------CYIRLKDFLRISGSL---KE 448

  Fly   628 DEKYTRILRYVEKEVDRILKTF-RKQRDDPPLARNFPPIAGRIHWCRALSLHITELMDAVMEHV- 690
            ::.|     |..|...:.:|.| .|.:...........:.|.:.....|: |:|||  .::||:
pombe   449 EQSY-----YGLKNSIKQIKAFENKLKYIQSFHEKHQQLIGALSEVYGLT-HLTEL--EILEHLN 505

  Fly   691 ----VLSSLPMAKD-------------------LDVRYHNVLGILQEYEDEIVSIWLDQDVSVAD 732
                |.:.|.:.||                   |:..|:|.:.:|   |||:::
pombe   506 KKEHVFNILTVFKDLQSLNVLDISLKGVNAWNSLETSYYNCMTVL---EDEVIA----------- 556

  Fly   733 ACLLQPLL--SLQGDKLFVNLHPTIPLLIREAKMLAKLDIELPIVAATLMSRQQYFITIQDSLNC 795
              .|:.||  |....::|..|....||..|     .::...:......|::|      |:..|:.
pombe   557 --QLKSLLQYSKTSSQMFTTLMRFQPLFFR-----TRVRTSISDCLHLLVNR------IKQELDL 608

  Fly   796 LIKMFLSTVRAVKL----EVR--PLFLPQLVRLTAMLKPGLH----TINWT-NQNWTEFYERCKQ 849
            |...|...|...:|    |:|  |:....::..| .||..||    .||.. .::|..|.:..:.
pombe   609 LKTRFTEDVSDTELIAMNELRNLPMASSAIIWAT-QLKNRLHEYTKNINIIFGEDWNNFPDGFEL 672

  Fly   850 AIESFDVLVARVHD--IYSNRILHVLMWMQDVSLQIL--PADDEIWTVDEFLERSEEA------- 903
            .:|.. .|..|:..  |::|       |:.|||.:.|  ..|.:|:    :|.:||.|
pombe   673 KVECI-TLQKRLDTNLIFTN-------WINDVSSRNLNFDFDSKIF----YLTQSESAESPLRLS 725

  Fly   904 ----------CRK----AAIELNRKSQMVSEAVEEVLSLVDRATAAFKEIAGDDVITLFDAATPK 954
                      |::    |.:..|..||::     |:.|.:.|    .:.||    :.|.|:....
pombe   726 VSIDFDPCSFCKEIRTLAHLGYNIPSQLM-----ELASCLQR----IQLIA----MCLIDSVQSF 777

  Fly   955 GDNSGSGGRKPEDGGGGGGGAAAPSTSGGGGGGQQQDWS------------ILWSCFENPLSLLS 1007
            .|.|....:..|:                  ....|::.            |.|:.|  .:..||
pombe   778 NDVSFEISKTEEE------------------RFLLQEYELAVRQHIVTGLFISWNDF--IVGNLS 822

  Fly  1008 TTESLPKGMQDMVCNAVVEMRRY-YSRKVIDVLIKVIRAAL--------DTLRRRFIADENETVF 1063
            |......|.::.:.|....:..| |....:..|:...|.|:        :.|.:..|.:.:..:|
pombe   823 TPPKCAIGKRNFLKNIHPNVENYAYQFSSLTSLLMNKRNAISHTYMQIQEQLFQLDICEYSGDIF 887

  Fly  1064 KKPVFALHAQLQ-------------IPHVVIKPNLDELQDILVTAGKNITGIAKGVAQWSSGKDP 1115
                ..:..:||             :|..|...|| ..||:|::..:......|.....|..::.
pombe   888 ----LTIQRKLQDLIDLLYVNGYSNLPPFVRALNL-RFQDLLISRCRKFLSFFKTTILTSGNENN 947

  Fly  1116 ------------------PQVSMTVQ-------PRVGRNHNESTGGGKSRRRKIY----CLAS-- 1149
                              ...::|:|       |.|.|...:|          ||    ||.|
pombe   948 DLKSKFSSDMYEKLRGFLKPTNLTIQRNIIEFDPPVYRKKEDS----------IYLLDMCLQSVV 1002

  Fly  1150 -------EERPQMPHMLKSFYSAIMDNKEVAKAVNQLASCTKNVKPEIQTYIKRWKPYHFLWKND 1207
                   :...|....|..|:..|          |:|.|....:...:..:......|...||
pombe  1003 NIPLLSIKTTAQRNCTLIGFFPVI----------NRLESEILGIFESLLFHFDSILGYQNYWK-- 1055

  Fly  1208 RTTRQLMEFGLQEFETTLRCLSDLDANLLVEPDMEVFGQC--VAVYNEKLKYGLAIEIKSCNHKI 1270
                        :.|..|. |:.|  |||::.::....||  :::|...||..:....|..:.||
pombe  1056 ------------KVEPFLN-LNSL--NLLLKSELFQLDQCYSLSLYLIHLKSEVDEIGKVTDFKI 1105

  Fly  1271 GQAMKKKYKKEMDYVYAVINE------------MDRKLDRPIRDLDDVRMIMETLGKIREQEVDM 1323
            ......::|.:   ||..:.|            :.::.:..:.:|||....:.|          :
pombe  1106 FSVNNTEFKSQ---VYLYLREWINALFDRFTFLLGKESEHLLNELDDTHSSLST----------V 1157

  Fly  1324 ELRIDPIEEAFNVLT------RYEVQVERE--------------------QFDLVDNLRATFQNL 1362
            :..::..|...|.|.      .|::.||.:                    .|.|:.::.:.:::|
pombe  1158 DFTVNNTESLINSLKIFKKAGCYKLNVEHKIITYQNYEMTFNDCDAFSEFNFSLLKDITSKWKDL 1222

  Fly  1363 LAGALQAQVKLLDMQPAFQDDLRTNLDNFKQ----DKISYVTEYRTAGPMQAGLTPREASDRLIL 1423
            |......::||.:.    :|::..|...|.:    :.:|.::|:..:..........|.|..:..
pombe  1223 LESFECRRLKLENN----KDEILRNFSEFAKRVNTETLSLISEWCASSLSLIKANYDEFSSTVDD 1283

  Fly  1424 FQNRFEGMWRRLQTYQSGEELFGLPQTDYPELGQIRKELNL---------LQ----KLYKLYNDV 1475
            |..||.         ::.|:..   ...|     |:|:|.:         :|    .|||.:.||
pombe  1284 FLFRFS---------KATEQCL---MVKY-----IKKDLEIEIEESCDFSIQTEEIHLYKKFKDV 1331

  Fly  1476 I----DRVSSYYDIPWNEVDIEEINNELMEFQNRCRKLPKGLKEWPAFHALKKTIDDFNDMCPLL 1536
            |    :.:....:..|...|...::.:.....|....:....:.:..|...|::::...|...||
pombe  1332 ISSNLEFIVEIKNTRWKLFDTATLSVQTTHQINALESVHTSFQHFKLFTNTKQSLNQLKDCTLLL 1396

  Fly  1537 ELMANKAMKPRHWQRIMDVTRYIFEFDSEGFSLKNILEAPLLKHKEDIEDICISAMKEKDIEAKL 1601
            :.:.:..:||.||..:.::|:...:.|.|...:.:||...|..|:..|..:..||:.|.::|.:.
pombe  1397 QKLKSCPLKPVHWISLFEITKSTEQLDFEKLLVSDILGIDLQAHESFITTLLNSAVVEANLENQF 1461

  Fly  1602 KQVTNEWSVHELQFMSFNNRGELLLRGDTTAETIGQLEDSLMVLGSLLSNRYNAPFRKQIQQWVY 1666
            .:|.:.|......|.||..|..:::   ...|.|..:|.::..|..:.::|:    .|.....:.
pombe  1462 NEVHSFWKNSYFSFKSFKGRNYIVV---GCQELIDAVEKNMDSLNLIKTSRH----FKDGDMNIT 1519

  Fly  1667 DLSNSNEILER----WLLVQNMWVYLEAVFVGGDIAKQ-LPKEAKRFSKIDKSWQKIMQRAHETP 1726
            ||.:..:|:.:    |..:|.:|.:|.|:|......:| ||:.|..|....|::..::
pombe  1520 DLQSKMKIIVKFLNIWKEIQQIWTHLSAIFYESTYIQQLLPELAASFFNSSKTYMHLV------- 1577

  Fly  1727 GVVACCVGDDLLKQL--------LPHLQEQ-------LEICQKSLSGYLERKRMMFPRFFFVSDP 1776
                     .|||:.        :|.|.|.       ||..:|||..|.|.:|....|.:|:.|.
pombe  1578 ---------TLLKERSYLYKVSNIPSLLESAAKLSTTLEDSKKSLLKYFELQRHKISRLYFLGDD 1633

  Fly  1777 ALLEILGQASDSHTIQNHLLNIFDNTKSVKFHDVEYNKMMAIISSEGEMIQLDRAIRAEGSVET- 1840
            .|:|::....|...|...::.::...:|: ..|.|...:....::||..:..|..|....:.:.
pombe  1634 DLMELISNPCDPFVINKQIIKLYPGIRSL-IVDTENTNINGCTTNEGNELLFDNPICLLDNTQPL 1697

  Fly  1841 -WLTQLLVTAQASLHSIIRTAYATIND------PNFTLLSFLEKAPAQIGLLGIQMVWTRDAEMA 1898
             |::.|....:|:|..:..|::..|.|      .|.....:..:.|:||.||.::.....:.|..
pombe  1698 HWISSLEPFLKATLFQLFSTSFQQIRDFYYNKSRNVFCKEWFLRYPSQITLLSLRCTLCHEIETG 1762

  Fly  1899 LMRGRERKVMMETNNKFLEMLNTLIDQTTRNLTKRERTNFETLITIHVHQRDIFDILCRMNIKSA 1963
            :.......|....|:. :..|..|.|:...::.|:....|..|:    |.::...:||:   .|.
pombe  1763 IADCCLDAVFNFINDG-ISSLVLLADENELSIKKKVTLMFNELL----HFKETVGLLCK---NSF 1819

  Fly  1964 NDFEWLKQCRFYFKEDLD--KTWISVTDVTFTYQNEYLGCTDRLVITPLTDRCYITLAQALTLSM 2026
            |::.|.::.:.:::||.|  ...|.:..:.|.|..||....|.:|.|.||..|:..|..::..::
pombe  1820 NNYFWSREVKAFYREDHDDEAVVIKMFSLEFIYAFEYSELDDPIVYTDLTRNCFSVLLHSIASNL 1884

  Fly  2027 GGAPCGPAGTGKTETVKDMGKTLAKYVVVFNCSDQMDYRGLGRIYKGLAQSGSWGCFDEFNRIEL 2091
            ||:|.||||||||||||.:...|.|.|.||||.:..:|:.:.||..||||.|::.|||||||::.
pombe  1885 GGSPIGPAGTGKTETVKAVSAYLGKNVFVFNCDNAFNYKTIQRILSGLAQIGTYICFDEFNRLDS 1949

  Fly  2092 PVLSVAAQQVAVVLTAKKEKRKTFLFTDGDTIEMNPEF----GIFITMNPGYAGRKELPENLKIQ 2152
            ..||..:..:         :|...|.:..|.:..:|..    .||:||||||.||.:||.|||..
pombe  1950 GTLSAISYDI---------QRIQSLVSHSDGLCQSPILLDAPTIFVTMNPGYLGRFKLPSNLKKL 2005

  Fly  2153 FRTVAMMVPDRQIIIRVKLASCGFLENITLARKFYTLYKLCEEQLTKQVHYDFGLRNILSVL--- 2214
            ||.:.|..||.:.|..:...|.||.|:..|::...:.:..|...|:..:|||||||.:..|:
pombe  2006 FRPIWMGSPDNKKICEILFLSFGFKESSLLSQVLDSFFLCCSGSLSNCLHYDFGLRAMKVVIKAA 2070

  Fly  2215 -RTLGAAKRRNSKDTESTIVMRVLRDMNLSKLIDDDEPLFMSLVSDLFPNQTLEKTNYPELEA-- 2276
             |..|..|::|:...|..|:...:|::....||..|.|||.......|        |:|.::|
pombe  2071 KRIKGFLKKKNTICQELEILWYAIREVLYPSLIYQDIPLFFKAEESYF--------NFPAVKANA 2127

  Fly  2277 --------AILQQTDEASLVYHPPWV-LKLIQLYETQHVRHGIMTLGPSGAGKTTCIHTLMKAMT 2332
                    ..::||...:...:..:: ||::|||:.....:||:.||.:|:||:.....|..|:.
pombe  2128 FIDPDNFEVNIEQTLSKNFFGNNQYLKLKIMQLYQMSEAYNGIILLGKTGSGKSQIFRILQSALL 2192

  Fly  2333 QMGDNHREMRMNPKAITAAQMFGRLDVATNDWTDGIFSALWRKTLKLKAGEHVWLVLDGPVDSIW 2397
            .:|.:.....::|||:|...:||.:::.|.:||||:|:.|.|||......:....|.|..:...|
pombe  2193 NIGIDCIVYVISPKALTKESLFGSMNMDTREWTDGVFTKLLRKTRDSCYYKRYMFVFDDELSPEW 2257

  Fly  2398 IENLNSVLDDNKTLTLANGDRLTMAPTVKIIFEPHNIDNASPATVSRNGMVYMS----------- 2451
            :|.:||:|||||||||:||:|:.:.|.|||.||..::.:.:.||:||.|::.:|
pombe  2258 VEAMNSLLDDNKTLTLSNGERIALQPYVKIFFEADSVASLTRATISRCGLICISNIDDNILSSTD 2322

  Fly  2452 -----SSGLDSRPIVQAWLKNRAPGEKSTFSDLFDQTFVEVYNWGVQMVKLQMPVLQCNIVQQML 2511
                 :||..:.|:             .:.:|.|...|.:|....|.|
pombe  2323 KMLSFTSGATNYPL-------------GSSNDEFSTVFSKVLTDEVMM----------------- 2357

  Fly  2512 FILEGLIPVKKEDEQAVSMSSKESHDANKRLEHQKH---------VEEARRQSIGSQIVEDLPPE 2567
                          ..:|...|.|.|....:...|.         :::.:..:..|.|.|.|
pombe  2358 --------------NLISSCYKFSVDLQHIMNFTKQRFFTTFYSLLDQTKLFTRSSNITESL--- 2405

  Fly  2568 TSIEEKEDTCTPEHLHRLYIFALAWGLGGYLSTSDRQRMNLFVKESFPQLDYPKGSAHEN-TIFD 2631
             |.:|   .|  .:|.:...:.|||...|......|:|...::.:: ..:|.|:....|: :|.|
pombe  2406 -SFKE---LC--NYLKKKICYILAWCCTGDTDAKSRERFTHWLMQN-ASVDLPEIKDFEHVSILD 2463

  Fly  2632 FFVSPAGVWQSW-----KTLVTPYMYPELSTPDYL-SILVPIVDNVRIDYLIGTIANQERAVMVI 2690
            |.||..  .|||     |||       :.|...|. :.::|.:|.||....:.....:.|.|:..
pombe  2464 FDVSLE--TQSWYPIAGKTL-------KSSALKYAGNTVIPTLDTVRYAEFLNFSLTKNRCVIFC 2519

  Fly  2691 GEQGTGKTVIMKNFMK-KMNVESYMGRSFNFSSATSPYQFQRTIESYVE------KRVGVTFGPP 2748
            |..|:||:::|...:: :.:||..   :.|||.:||    .:::.|::|      :..|:|...|
pombe  2520 GPPGSGKSMLMLGTLRSRQDVEVI---ALNFSISTS----SKSVVSFLEQSTVYYRSTGMTIMCP 2577

  Fly  2749 GGRK--LIVFIDDINLPEINEWGDQITNEIV---RQSMDMKGF-YSLEKPGDFTTIVDVQYVAAM 2807
            ...:  |::|.|:||||...   :.:..:::   |..::.:|| :.|.|  ::.||.:: :|...
pombe  2578 KNHEKVLVLFCDEINLPRSR---NCLAEDVICFLRHMLEHQGFWHPLHK--EWVTIKNI-FVCGA 2636

  Fly  2808 GLPGG--GRNDIPSRLKRQFCVFNCNIPDNDSIDKIFRVIGEGHYNAKRGFVPEIRSLVKKLIVV 2870
            ..|..  ||||.|.|..|:..:...:.|::.|:..|:..:.|     |...:.:.::::..::..
pombe  2637 CNPSTDIGRNDFPERFLRRTVLIFVDYPESYSLVTIYNALLE-----KSALINQYKTIILNIVKA 2696

  Fly  2871 TRHLWQRTREKLLPTPAKFHYVFSLRDLSRIWQGMVG----TLSTVITSESVLMALWKHECTRVF 2931
            :...:|..||....:..  .||::.|||:| |  ::.    ..|...|:...|:.:|.||..||.
pombe  2697 SVKFYQVLRENFKSSTQ--GYVYTPRDLTR-W--LISFKNYAESYAETNNLSLIKVWYHEACRVL 2756

  Fly  2932 ADRFTTFQDKEWFGSELACLVREELGDSHSQMILPNP-VFVDFMRDAPEPTGEEGEDTDMELPK- 2994
            .||..:.::..|..:||..::..:.|:....:|.... :|.|.:::     |.|..|.....||
pombe  2757 LDRLVSQKECSWGMTELQKVIVTDFGEFEVSVIFEKQIIFTDILKN-----GLEFLDFASLRPKL 2816

  Fly  2995 --VYEPVHSHEVLRERLVMFLAQFNEMVRGSGMDLVFFPDAMLHLVKISRIIRHPRGSVMLVGVG 3057
              :|:..:|..                   ....|||..:.:.|:::..||:.:.....:|.|..
pombe  2817 ESLYKKFYSSH-------------------PNNTLVFVDETITHILRFHRILNNSGMHALLQGSV 2862

  Fly  3058 GSGKQSLTKLASFIAGYKTFQIALTRSYNVANFLEDLKLLYRTCGVQGKGTTFLFTDMDIKEE-- 3120
            |.|::::.:...::..:..|::...::|::.:|.::||.:....     |||.....:.|.|.
pombe  2863 GLGQKAVVEFVCWLNSFSLFELQKNQTYSIEDFEDNLKSILILA-----GTTNCKACLAINESIA 2922

  Fly  3121 ---GFLEYLNNILSSGVISNLFSRDEQAEIVQELTPVMKRENQRKTATPESVMDFFLARTCTNLH 3182
               |||:.|||:|::..:||.|.:::.|||.:.|.. :......|..:.|||.:.|:.....||.
pombe  2923 GVPGFLDLLNNLLTNSEVSNFFDQNDWAEIKKNLNK-LNEFQPLKFDSEESVTEIFMNNVFQNLC 2986

  Fly  3183 VAF-CFSPVGETFRSRVQRFPALVSGCTIDWLHPWPKDALVSVARHFLSH-FEIECTPAVKEELV 3245
            |.| .::.....|::. ...|||::.||||:.|.|...:::.:|...|.. ..:.........|.
pombe  2987 VVFYVYTSADVDFQTN-SLSPALLNRCTIDYYHSWDYHSMLQIANEVLQETISLNALDHDNPNLK 3050

  Fly  3246 NALG-SIQDIVAE------TSQEY-FQRFRRATHVTPKSYLNFIAGYKNIYQMKQQELRDGVEKM 3302
            |..| ||.|.||:      ||..: |:...:.::.:...::.|:..:..|:.....:|.....::
pombe  3051 NIKGSSIYDAVAQAVVNTHTSIVWEFKHLGKTSYFSCLHFIRFLNTFCLIFGRDANKLSKEKSRI 3115

  Fly  3303 DTGLEKLKEASASVEILKKDLVVMEEELVEASKNAESVL--VEVTERAMQAEIVKNQVLIVKDKA 3365
            :.|.:|:||.|..::..|:.|...:..|...:|.|...|  :..|::|::|:.|.:.      :|
pombe  3116 ENGFKKIKETSQGIDKFKEALSDQQNVLFSKTKTANDRLQCIIQTKQAVEAKKVYSL------QA 3174

  Fly  3366 EALVA----CIAHEKALAEEKLEAAKPALEEAENALNTIKPAHIATVRKLGRPPHLIMRIMD--C 3424
            ||.:.    .:..:|....:::..||||:.||..:::.||.||:..:|.|.|||..|...|:  |
pombe  3175 EASLQKKSFLLNEKKNSVMKEVSYAKPAVIEARKSVSDIKKAHLIELRSLSRPPMAIRITMEVVC 3239

  Fly  3425 VLILFKRKLHPCIPDAGTPCPKPSWQESLKMMASATFLLQLQNYPKDTINDEM-IDLL----QPY 3484
            .|:.|.               ...|:...:::....|:.::.||   .:..|: |:|.    |.|
pombe  3240 KLLGFS---------------ATDWKNVQQLLKRDDFIPKILNY---NLEKELSINLRRKIEQDY 3286

  Fly  3485 FRMEDYNMDMARRVCGDVAGLLSWTKAMSFFHSVNKEVLPLKANLTMQEARLKLAMDDLAGAEEQ 3549
            |....:..|...|.......||.|.|::..:..|.:::.||.:.:.    ||||   :...|||.
pombe  3287 FSNPIFTFDSVNRASKACGPLLLWIKSICNYSKVLEKLEPLNSEVD----RLKL---EQKNAEEC 3344

  Fly  3550 LRER-------EEALQAVKDQYDKAVGEKQRLTDAANVCLRKMTAATALINGLSDEKHRWTNQSK 3607
            ::|.       :|.|..::::|...:.|...:....:....||..:..:|..||.|::.|:....
pombe  3345 IQETIAACKDLDEKLLQLQEEYASMISEIHSMELQMDEVKCKMQRSIEVITDLSIERNEWSGFLN 3409

  Fly  3608 EFKIQLGKLVGDVLLATGFLSYCGPYNQEFRANLIKTWMGILKQKNIPFTTGL--NIINMLVDSS 3670
            .:..::..|||:.|:...|:.|.|..:...|..|......|:.....|.:...  ..|...|.:|
pombe  3410 LYPKRMWNLVGESLMEASFVVYAGNLDPSMRIFLRNKCEPIISSFGFPISKSAVRTNIERCVQTS 3474

  Fly  3671 TVSEWTLQGLPNDELSVQNALIATKSSSYPLLVDPQTQ----------GKIWIKCKEDRNELQIT 3725
            ..|:: .:.|  .:.|::|..|..::.|..|::||.:|          ||          ...:.
pombe  3475 IESKY-YKNL--TDYSLENIYIIQENKSPLLIIDPSSQILDILPSLYKGK----------ASDLI 3526

  Fly  3726 SLNHKYFRTHLEDSLSLGRPLLIEDVGIDLDPVIDNVLEKNFIK-SGSIEKVLVGDKECDVMPGF 3789
            |.::|.|:..::.:|..|..::|:|..: .|..|:.:|:..|.. ||.::.....|.
pombe  3527 SFSNKSFQNQIKLALLSGSAIIIKDAEL-WDVSIEPLLKPEFFTGSGEVQTTFAKDT-------- 3582

  Fly  3790 MLYITTKLP-NPAFSPEVSAK---------TSIIDFTVTMRGLEDQLLGRVILMEKSDLEAERVA 3844
               ||..|| |..|..||.:.         .::::||:::..||.|:|..||.:::..:..::..
pombe  3583 ---ITITLPLNIIFFSEVQSNELENKASKFMNVVNFTLSISLLETQMLKSVISVQEPGVFKQKDN 3644

  Fly  3845 LFETVMQNQRNMKELEANLLLRLSSSQGSLVDDEALIEVLRVTKTTAEEVNQKLKISEVTERKIM 3909
            .|...:..:|.::.|:..||..|.||..::|..:.::.:|:..|...|.:......|:...||:
pombe  3645 CFTLKLSIERQIRSLQEQLLKTLCSSNENIVGTDEIVVLLKNLKEKHETIRLAYSESQSINRKV- 3708

  Fly  3910 KAREEFRAVAKRGSILYFLIVEMSNVNAMYQNSLKQFL---VIFNHSITKSTKSSVTEERINIIL 3971
                                   ..:...|:.|:|.||   |:|.|.|  |.|.|
pombe  3709 -----------------------DELIRRYKLSIKSFLSVVVVFQHFI--SLKKS---------- 3738

  Fly  3972 RYLTYEVYKFTNRSLYERHKQLFTLMLAIKIDYHNGNISHEEFLTFIKGGASLDLNAVTPKPFRW 4036
                   |.|:...::....|:..::|      .|.|   ::|.:.|...    |..:..:.|.:
pombe  3739 -------YSFSFNFIWSTFHQMLNVVL------ENRN---QDFKSLIMDA----LRDLIRRCFLY 3783

  Fly  4037 ILD---ITWLNLVEI----SKLETFSTVL----QVIELNEKDWRCWYECEKPENEEIPCGYNAI- 4089
            |..   :.:|.|:..    .:.|:...:|    :.:|| |:.:..::|.....||.  .|..::
pombe  3784 IFPEDRVLFLFLLMFFFFPKETESLRKLLIVNGKTLEL-EQSYLNFFETCSDSNER--GGLESLF 3845

  Fly  4090 -------LDGFRKLLLIRSWCPDRTISQAKKYIEESLGPEYSEMQILDLEEMWLESEPRTPFVCL 4147
                   :..|...:|..:.|.:..:.........:...|:|.::...|:.:..|||.|.|.:..
pombe  3846 FKTHASNIQNFCTEVLANTHCEEDCLKLLYDLWSSAFKVEFSNIKYDFLKIINDESESRMPTIVY 3910

  Fly  4148 LSIGSDPTTQIGALAKQKSIVLKSVSMGQGQEYHARKMIIESMAIGG---------WVLLQNVHL 4203
            |....:..:.:......::|...:||:|..:.        ||:|...         |:.:.|:||
pombe  3911 LMENCEIDSLLQNAKIPQNIKKLTVSLGSAEN--------ESLADSYLKLASTEPLWLFINNIHL 3967

  Fly  4204 SLPFCSEIIDMLVESEHIDDSFRMWVTTEPHNEFPIGLLQMALKFTNEPPQGIRASLKRSYQSFT 4268
            |.|:..::...:  |.|:..:.|:...:|.||:.|..||.::           |:.:.....||.
pombe  3968 STPWAEKLPSKM--SNHLHKNSRIVCLSEIHNQLPHQLLCIS-----------RSIVFNKQTSFK 4019

  Fly  4269 QDFLD----YTSATQWPP-----LLYTVAFLHTIVQERRKFGPLGWNIPYEFNQADFAASVQFIQ 4324
            .:.|:    ..:.|...|     |.:.:::||..:.|...|....|..|..|:.:||....:.:.
pombe  4020 NNLLNLLELLPTMTHTLPHNRFRLFFFLSWLHATLAEIYCFTCSSWKEPCYFDDSDFYFGTKILC 4084

  Fly  4325 N------HLDEMDPKKGVSWQTLVYMIGEVQYGGRVTDDFD--------KRLLTTFTSVWFCEPL 4375
            |      ||:|.      ||.|...::..|.||.:|:...|        |||:..|.:......|
pombe  4085 NILYRNVHLEEF------SWGTFKDLLLNVVYGPKVSASSDFIALDKILKRLIAQFKTQISSNIL 4143

  Fly  4376 LSNSFEFYKGYKVPGTKSLQGFIDYINSLPA------YDTPE 4411
            |:::|:|...|::    :.....:.|..||.      .|.||
pombe  4144 LTDNFKFILPYEI----TFSSAKEVIGQLPDEIPPGWLDIPE 4181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9492	NP_001287256.1	DHC_N1	283..843	CDD:285571	115/577 (20%)
		DYN1	1178..4372	CDD:227570	789/3470 (23%)
		DHC_N2	1458..1861	CDD:285579	94/441 (21%)
		P-loop_NTPase	1994..2222	CDD:304359	91/235 (39%)
		P-loop_NTPase	2309..2444	CDD:304359	52/134 (39%)
		P-loop_NTPase	2662..2926	CDD:304359	65/282 (23%)
		P-loop_NTPase	3025..3287	CDD:304359	67/276 (24%)
		MT	3300..3646	CDD:289543	86/365 (24%)
		AAA_9	3674..3890	CDD:289547	52/236 (22%)
		Dynein_heavy	4031..4713	CDD:281078	90/438 (21%)
dhc1	NP_001342921.1	DHC_N1	251..816	CDD:312031	128/685 (19%)
		DHC_N2	1322..1718	CDD:312039	89/419 (21%)
		DYN1	<1605..4196	CDD:227570	681/2866 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	230	1.000	Domainoid score	I503
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47047
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.670