DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9492 and DNAH12

DIOPT Version :9

Sequence 1:	NP_001287256.1	Gene:	CG9492 / 41171	FlyBaseID:	FBgn0037726	Length:	4724	Species:	Drosophila melanogaster
Sequence 2:	NP_001352957.1	Gene:	DNAH12 / 201625	HGNCID:	2943	Length:	3960	Species:	Homo sapiens

Alignment Length:	4030	Identity:	1244/4030 - (30%)
Similarity:	2002/4030 - (49%)	Gaps:	478/4030 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   989 QQDWSILWSCFENPLSLLSTTESLPKGMQ-----DMVCNAVV-----EMRRYYSRKVIDVLIKVI 1043
            ||:|      .::.|.|:  .|||.:|.:     :.:.|.|.     .|:||.   |..||:|..
Human   112 QQEW------LDHMLRLI--PESLKEGKEREELLESLINEVSSDFENSMKRYL---VQSVLVKPP 165

  Fly  1044 RAALDTLRRRFIADENETVFKKPV----------------FALHAQLQIPHVVIKPNLD----EL 1088
            ..:|:        ||...:.:.||                ..:.:.|.|.|..:|..||    ..
Human   166 VKSLE--------DEGGPLPESPVGLDYSNPWHSSYVQARNQIFSNLHIIHPTMKMLLDLGYTTF 222

  Fly  1089 QDILVTAGKNITGI-AKGVAQWSSGKD---------PPQVSMTVQPRVGR--NHNESTGGGKSRR 1141
            .|.::.   :.||| |||.....|.|.         ..::..|..|:|..  ...|:..|.|..:
Human   223 ADTVLL---DFTGIRAKGPIDCESLKTDLSIQTRNAEEKIMNTWYPKVINLFTKKEALEGVKPEK 284

  Fly  1142 RKIY--CLASEERPQMPHMLK--------------------------------SFYSAIMDNKE- 1171
            ...:  |:::....|:..:|:                                .||....|.::
Human   285 LDAFYSCVSTLMSNQLKDLLRRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDN 349

  Fly  1172 VAKAVNQLASCTKNVK----------------PEIQTYIKRW-----------------KPYH-- 1201
            |...|.::|...:||:                .|:..::..|                 |.|.
Human   350 VLSLVERIAEALQNVQTIPSWLSGTSTPVNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETY 414

  Fly  1202 ---FLWKNDRT------TRQLMEFGLQEFETTLRCLSDLDANLLVEPDMEVFGQCVAVYNEKLKY 1257
               :.|..|.|      |.|..:....|:...:.....|.:.:::.|.. :....|.:..|.||.
Human   415 VEKYNWLLDGTAVENIETFQTEDHTFDEYTEFIEKFLSLASEIMLLPQW-IHYTMVRLDCEDLKT 478

  Fly  1258 GLAIEIKSCNHKIGQAMKKKYKKEMDYV---YAVINEMDRKLDRPIRDLDDVRMIME---TLG-- 1314
            ||..:.|:..:.:...:..||:||.:.:   :..|.|...|:.....::.|:...:|   |:|
Human   479 GLTNKAKAFANILLNDIASKYRKENECICSEFEAIKEHALKVPETTEEMMDLISYVEKARTVGIE 543

  Fly  1315 ----KIREQEVDMELRID----PIEE-AFNVLT----RYEVQVEREQFDLVDNLRATFQNLLAGA 1366
                :|:|.:..|...:|    |.|: |.|...    |....:..|..:|::|.:...:|.|...
Human   544 ELILRIQESKRQMSYFLDVFLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHKKENELMAK 608

  Fly  1367 LQAQVKLLDMQPAFQDDLR--TNLDNFKQDKISYVTEYRTAGPMQAGLTPREASDRLILFQNRFE 1429
            .:..:..::.:....::..  ..|:..:|    |||:.|.                   .|.|.:
Human   609 REKLILEIEKESRRMEEFTEFAELERMQQ----YVTDVRQ-------------------LQKRIQ 650

  Fly  1430 GMWRRLQTYQSGEELFGLPQTDYPELGQIRKELNLLQKLY----------KLYNDVIDRVSSYYD 1484
            .....:|.....||||....|.||||.:::..:...||.:          |.:.|     ..:.|
Human   651 ESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMD-----GGFLD 710

  Fly  1485 IPWN--EVDIEEINNELME----FQNRCRK--------------LPKGLKEWPAFHA-------L 1522
            :...  |.|:||.:.|:.:    ||.:.:|              ..:.::|.|..:|       :
Human   711 LNGESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEEPKDNATITMCSTV 775

  Fly  1523 KKTIDDFNDMCPLLELMANKAMKPRHWQRIMDVTRYIFEFDSEGFSLKNILEAPLLKHKEDIEDI 1587
            .:.|..|.:..|.:.::.|..|:.|||::|.::..|....|| |.:|:.:|:..|..:.|..|.|
Human   776 MEQIKAFKEYIPTVSILCNPGMRARHWKQISEIVGYDLTPDS-GTTLRKVLKLNLTPYLEQFEVI 839

  Fly  1588 CISAMKEKDIEAKLKQVTNEWSVHELQFMSFNNRGELLLRGDTTAETIGQLEDSLMVLGSLLSNR 1652
            ...|.||..:|..:..:...|.........:.:.|..:|......:.|  |:|.::...::..:.
Human   840 SAGASKEFSLEKAMNTMIGTWEDIAFHISLYRDTGVCILSSVDEIQAI--LDDQIIKTQTMRGSP 902

  Fly  1653 YNAPFRKQIQQWVYDLSNSNEILERWLLVQNMWVYLEAVFVGGDIAKQLPKEAKRFSKIDKSWQK 1717
            :..||..:|:.|...|....|.::.||.||..|:|||.:|...||.:|:|:|.::|..:|:.|:.
Human   903 FIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFCSEDIMQQMPEEGRQFQTVDRHWRD 967

  Fly  1718 IMQRAHETPGVVACCVGDDLLKQLLPHLQEQLEICQKSLSGYLERKRMMFPRFFFVSDPALLEIL 1782
            ||:...:.|.|:|......||:: |.:..|.||...|.|:.|||:||:.||||||:|:..:||||
Human   968 IMKFCAKDPKVLAATSLTGLLEK-LQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEIL 1031

  Fly  1783 GQASDSHTIQNHLLNIFDNTKSVKF---HDVEYNKMMAIISSEGEMIQLDRAI---RAEGSVETW 1841
            .:..|...:|.||...|:....::|   .|::     |:.|||||.::|...|   .|.|:||.|
Human  1032 SETKDPLRVQPHLKKCFEGIAKLEFLPNLDIK-----AMYSSEGERVELIALISTSAARGAVEKW 1091

  Fly  1842 LTQLLVTAQASLHSII---RTAYATINDPNFTLLSFLEKAPAQIGLLGIQMVWTRDAEMALMRGR 1903
            |.|:......|:|.:|   |.||     |......::.:.|.|:.|...||.||.:.:..:..|.
Human  1092 LIQVEDLMLRSVHDVIAAARLAY-----PESARRDWVREWPGQVVLCISQMFWTSETQEVISGGT 1151

  Fly  1904 E--RKVMMETNNKFLEMLNTLIDQTTRNLTKRERTNFETLITIHVHQRDIFDILCRMNIKSANDF 1966
            |  :|...|..|:    ||.:::.....|:|:.||....|:||.||.||:...:.:|.:....||
Human  1152 EGLKKYYKELQNQ----LNEIVELVRGKLSKQTRTTLGALVTIDVHARDVVMDMIKMGVSHDTDF 1212

  Fly  1967 EWLKQCRFYFKEDLDKTWISVTDVTFTYQNEYLGCTDRLVITPLTDRCYITLAQALTLSMGGAPC 2031
            .||.|.|:|::.:..:..|...:|.:.|  ||||.:.||||||||||||.||..|..|::||||.
Human  1213 LWLAQLRYYWENENARVRIINCNVKYAY--EYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPE 1275

  Fly  2032 GPAGTGKTETVKDMGKTLAKYVVVFNCSDQMDYRGLGRIYKGLAQSGSWGCFDEFNRIELPVLSV 2096
            ||||||||||.||:.|.||...|||||||.:||..:|:.:||||.||:|.||||||||||.||||
Human  1276 GPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSV 1340

  Fly  2097 AAQQVAVVLTAKKEKRKTFLFTDGDTIEMNPEFGIFITMNPGYAGRKELPENLKIQFRTVAMMVP 2161
            .|||:..:..|.::|...|:| :|..:::||...:.||||||||||.|||:|||:.|||||||||
Human  1341 VAQQILCIQRAIQQKLVVFVF-EGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVP 1404

  Fly  2162 DRQIIIRVKLASCGFLENITLARKFYTLYKLCEEQLTKQVHYDFGLRNILSVLRTLGAAKRRNSK 2226
            :..:|..:.|.|.|||....|:.|....|:||.|||:.|.|||:|:|.:.:||...|..|.:...
Human  1405 NYALIAEISLYSYGFLNARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPN 1469

  Fly  2227 DTESTIVMRVLRDMNLSKLIDDDEPLFMSLVSDLFPNQTLEKTNYPELEAAILQQTDEASLVYH- 2290
            :.|..:::|.::|:|..|.:..|.|||..:.|||||...|.:.:|.|    .|:...||..|::
Human  1470 ENEDILLLRSIKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHE----FLECAHEACNVHNL 1530

  Fly  2291 PP---WVLKLIQLYETQHVRHGIMTLGPSGAGKTTCIHTLMKAMTQM-----GDNHREM--RMNP 2345
            .|   ::.|:||.||...||||.|.:|...|.||..:|.|...:|.|     |:..:.:  .:||
Human  1531 QPVKFFLEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVNP 1595

  Fly  2346 KAITAAQMFGRLDVATNDWTDGIFSALWRKTLKLKAGEHVWLVLDGPVDSIWIENLNSVLDDNKT 2410
            |:||..|:||:.|..:::|||||.:..:|:....:..:..|:|.|||:|::|||::|:||||||.
Human  1596 KSITMGQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTVLDDNKK 1660

  Fly  2411 LTLANGDRLTMAPTVKIIFEPHNIDNASPATVSRNGMVYMSSSGLDSRPIVQAWLKNR-----AP 2470
            |.|.:|:.:.|:|.:.:|||..::..||||||||.||:|:..|.|...|:|.:||.:.     .|
Human  1661 LCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLNSLKGPLCEP 1725

  Fly  2471 GEKSTFSDLFDQTFVEVYNWGVQMVKLQMPVLQCNIVQQMLFILEGLIPVKKEDEQAVSMSSKES 2535
            ..::....||........|...:..|..:|....|:|..:..:.|.|:
Human  1726 EYQALLRGLFAWLIPPSLNQRKKKCKELIPTSNSNVVVSLTRLFEVLL----------------- 1773

  Fly  2536 HDANKRLEHQKHVEEARRQSIGSQIVEDLPPETSIEEKEDTCTPEHLH----RLYIFALAWGLGG 2596
                                  ..:||:.|            |.:|:.    ..:||:|.|.:||
Human  1774 ----------------------CNVVENDP------------TSKHIRVWIMACFIFSLIWSIGG 1804

  Fly  2597 YLSTSDRQRMNLFVK-------------ESFPQLDYP---KGSAHENTIFDFF--VSPAGVWQSW 2643
            ...|..|:..:.|::             :|..:.:.|   ||     .::|:.  :...|.|..|
Human  1805 SCDTDGRRVFDTFIRLIILGKDDENPVPDSVGKWECPFDEKG-----LVYDYMYELKNKGRWVHW 1864

  Fly  2644 KTLV--TPYMYPELSTPDYLSILVPIVDNVRIDYLIGTIANQERAVMVIGEQGTGKTVIMKN-FM 2705
            ..|:  |.....::...|   |:||.:|.:|..:|:.......:.::.:|..||||:|.:|: .|
Human  1865 NELIKNTNLGDKQIKIQD---IIVPTMDTIRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLM 1926

  Fly  2706 KKMNVESYMGRSFNFSSATSPYQFQRTIESYVEKRVGVTFGPPGGRKLIVFIDDINLPEINEWGD 2770
            ..:..:.|.....|.|:.||..|.|..|.:.::||....||||.|:|.|:||||:|:|.:.::|.
Human  1927 NHLEKDQYFPFYINLSARTSANQVQNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGA 1991

  Fly  2771 QITNEIVRQSMDMKGFYSLEKPGDFTTIVDVQYVAAMGLPGGGRNDIPSRLKRQFCVFNCNIPDN 2835
            |...|::||..|...:|.| |.....|:||::.:||||.||||||.:..|..|.|.:.:.|...:
Human  1992 QPPIELLRQFFDCGHWYDL-KDTSKITLVDIELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSD 2055

  Fly  2836 DSIDKIFRVIGEGHYNAKRGFVPEIRSLVKKLIVVTRHLWQRTREKLLPTPAKFHYVFSLRDLSR 2900
            :::.:||..| ...|.....|.||...:..:::..|..:::::.|.|||||.|.||.|:|||.||
Human  2056 ETMVRIFSSI-VAFYLRTHEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSR 2119

  Fly  2901 IWQGMVGTLSTVITSESVLMALWKHECTRVFADRFTTFQDKEWFGSELACLVREELGDS-HS--- 2961
            :.:|.:......:.::..::.|:.||..|||.||.....|:.|.......::::...:| ||
Human  2120 VIRGCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKESFHSIFS 2184

  Fly  2962 ----------QMILPNPVFVDFMRDAPEPTGEEGED-TDMELPKVYEPVHSHEVLRERLVMFLAQ 3015
                      :..|.|.:|.|:|.  |:   .||:| ..:|:|.::   |..:|:.:    .|.:
Human  2185 HLRKQNAPVTEEDLRNLMFGDYMN--PD---LEGDDRVYIEIPNIH---HFSDVVDQ----CLDE 2237

  Fly  3016 FNEMVRGSGMDLVFFPDAMLHLVKISRIIRHPRGSVMLVGVGGSGKQSLTKLASFIAGYKTFQIA 3080
            :|: ...:.|:||.|...:.||.:|.|:::...|:.:|||:||||:||||:||:.:|....||..
Human  2238 YNQ-THKTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIFQPE 2301

  Fly  3081 LTRSYNVANFLEDLKLLYRTCGVQGKGTTFLFTDMDIKEEGFLEYLNNILSSGVISNLFSRDEQA 3145
            :::||.:..:.||:|.|.|..|::|:.|.||.||..||||.|||.::::|::|.:.|:|:.||:.
Human  2302 ISKSYGMNEWREDMKGLLRNVGMKGQKTVFLITDTQIKEEAFLEDIDSVLNTGEVPNIFAADEKQ 2366

  Fly  3146 EIVQELTPVMKRENQRKTATPESVMDFFLARTCTNLHVAFCFSPVGETFRSRVQRFPALVSGCTI 3210
            |:::.:.||.:..|:....:|.::..||:.|...||||...|||:|:.||:|:::||:|::.|||
Human  2367 EVMEGVRPVAQAGNKHDELSPLALFAFFVNRCKDNLHVVVAFSPIGDAFRNRLRQFPSLINCCTI 2431

  Fly  3211 DWLHPWPKDALVSVARHFLSHFEIECTPAVKEELVNALGSIQDIVAETSQEYFQRFRRATHVTPK 3275
            ||...||:|||..||..||.  .:|.|...::|:|.........:.:.|:.:.....|..:||..
Human  2432 DWFQSWPEDALERVAVKFLE--TLELTEVEQQEIVPICKHFHTSIMDLSERFLHELGRHNYVTAT 2494

  Fly  3276 SYLNFIAGYKNIYQMKQQELRDGVEKMDTGLEKLKEASASVEILKKDLVVMEEELVEAS-KNA-- 3337
            |||..|..::.:...|:|.:.:..::...||:||..|.:.|..::.:||.::.:|.||. :||
Human  2495 SYLELIGSFRQLLTQKRQAVMEAKQRYMNGLDKLAFAESQVGEMQMELVELQPKLEEAKIENANM 2559

  Fly  3338 ------ESVLVEVTERAMQAEIVKNQVLIVKDKAEALVACIAHEKALAEEKLEAAKPALEEAENA 3396
                  |||.||.     :.:.||....|...|||...|.    |...|..|..|.||||.|.:|
Human  2560 MQVIEIESVQVEA-----KRQFVKLDEEIASGKAEEAQAL----KNECESDLAEAIPALEAALSA 2615

  Fly  3397 LNTIKPAHIATVRKLGRPPHLIMRIMDCVLILFKRKLHPCIPDAGTPCP-KPSWQESLKMMASAT 3460
            |:|:|||.|..|:.:..||..:..:|..|.::...|.......:||... ...|..|.|::....
Human  2616 LDTLKPADITIVKSMKNPPSGVKLVMAAVCVMKDIKPEKISDPSGTGGKILDYWGPSKKLLGDMN 2680

  Fly  3461 FLLQLQNYPKDTINDEMIDLLQPYFRME-DYNMDMARRVCGDVAGLLSWTKAMSFFHSVNKEVLP 3524
            ||..|:.|.||.|...::..::..:.|. :::.....:......||..|..||..:..|.|.|.|
Human  2681 FLRDLKEYDKDNIPVTVMQKIRSEYLMNPEFDPPKVAKASSAAEGLCKWIMAMEVYDRVAKVVAP 2745

  Fly  3525 LKANLTMQEARLKLAMDDLAGAEEQLREREEALQAVKDQYDKAVGEKQRLTDAANVCLRKMTAAT 3589
            .||.|:..:..|...|:.|.....:|.|.|..|:.::..:.:...||..|.|...:|.:|:..|:
Human  2746 KKARLSEAQKSLAETMELLNQKRAELAEVEHHLENLQMTFLEKTEEKAALEDQVELCAKKLERAS 2810

  Fly  3590 ALINGLSDEKHRWTNQSKEFKIQLGKLVGDVLLATGFLSYCGPYNQEFRANLIKTWMGILKQKNI 3654
            .||.||..||.||...:.:.:|....|.||||::.|.::|.|.:...||....|.|..:.|:|.|
Human  2811 QLIGGLGGEKSRWAQAADDLQITYENLTGDVLVSAGVIAYLGAFTSGFRQTCTKDWSMLCKKKKI 2875

  Fly  3655 PFTTGLNIINMLVDSSTVSEWTLQGLPNDELSVQNALIATKSSSYPLLVDPQTQGKIWIKCKEDR 3719
            |.:....:...|.|...:..|.:.|||.|..|:.|.:|......:||::|||.|...|||..|..
Human  2876 PCSEEFLLSKTLGDPVKIRAWNIAGLPTDTFSIDNGVIVNNCRRWPLMIDPQGQANKWIKNSEKE 2940

  Fly  3720 NELQITSLNHK-YFRTHLEDSLSLGRPLLIEDVGIDLDPVIDNVLEKNFIKSGSIEKVLVGDKEC 3783
            |:|.:..|:.. |.|| ||:.:..|.|||:|:||.:|||.::.:|.:...|.|.|:.:.:|:...
Human  2941 NQLSVIKLSDSDYMRT-LENCIQFGTPLLLENVGEELDPSLEPLLLRQTFKQGGIDCIRLGEVII 3004

  Fly  3784 DVMPGFMLYITTKLPNPAFSPEVSAKTSIIDFTVTMRGLEDQLLGRVILMEKSDLEAERVALFET 3848
            :....|..||||||.||.:.||::.|.|:::|.:|..||||||||.|:..|:.:||.||.||...
Human  3005 EYSFDFKFYITTKLRNPHYMPELATKVSLLNFMITPEGLEDQLLGIVVAKERPELEEERNALILQ 3069

  Fly  3849 VMQNQRNMKELEANLLLRLSSSQGSLVDDEALIEVLRVTKTTAEEVNQKLKISEVTERKIMKARE 3913
            ...|::.:|::|..:|..||||:|::::||:.|:||...|..:.|:.:|.:|:|.||.||.::||
Human  3070 SAANKKQLKDIEKKILETLSSSEGNILEDESAIKVLDSAKMMSNEITKKQQIAEKTELKIAESRE 3134

  Fly  3914 EFRAVAKRGSILYFLIVEMSNVNAMYQNSLKQFLVIFNHSITKSTKSSVTEERINIILRYLTYEV 3978
            .:|.:||..|:|:|.|.:::|::.|||.||..|:.::.:||..|.||.:.|:|:..:..:.||.:
Human  3135 GYRPIAKHSSVLFFSIADLANIDPMYQYSLTWFVNLYINSIHDSNKSKILEKRLRYLNDHFTYNL 3199

  Fly  3979 YKFTNRSLYERHKQLFTLMLAIKIDYHNGNISHEEFLTFIKGGASLDLNAVTPKPFRWILDITWL 4043
            |....|||:|:.|.||:.:|...:......|.::|.:..:.||.||......|.| .|:.|.:|.
Human  3200 YCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLLTGGVSLKSAEKNPDP-TWLQDKSWE 3263

  Fly  4044 NLVEISKLETFSTVLQVIELNEKDWRCWYECEKPENEEIPCGYNAILDGFRKLLLIRSWCPDRTI 4108
            .:...|:...|..:.|....:..:||..|:.::|.|.:.|...:..|:..:|::::|...||:..
Human  3264 EICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPHNAKFPAPMDKNLNELQKIIILRCLRPDKIT 3328

  Fly  4109 SQAKKYIEESLGPEYSEMQILDLEEMWLESEPRTPFVCLLSIGSDPTTQIGALAKQKSI---VLK 4170
            .....|:.:.||.::.|....||.:.:|:|....|.:.:||.|:||...:...|..||:   ..:
Human  3329 PAITNYVTDKLGKKFVEPPPFDLTKSYLDSNCTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQ 3393

  Fly  4171 SVSMGQGQEYHARKMIIESMAIGGWVLLQNVHLS---LPFCSEIIDMLVESEHIDDSFRMWVTTE 4232
            ::|:||||...|.|||..::..|.||.|||.||:   :|...:|.:... ||..:.|||:|:|:.
Human  3394 AISLGQGQGPIAAKMIKAAIEEGTWVCLQNCHLAVSWMPMLEKICEDFT-SETCNSSFRLWLTSY 3457

  Fly  4233 PHNEFPIGLLQMALKFTNEPPQGIRASLKRSYQSFTQDFLDYTSATQ-----WPPLLYTVAFLHT 4292
            |.::||:.:||..:|.|||||.|:|.:|.:||.:......::....:     |..||:.|.|.|.
Human  3458 PSSKFPVTILQNGVKMTNEPPTGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHA 3522

  Fly  4293 IVQERRKFGPLGWNIPYEFNQADFAASVQFIQNHLDEMDPKKGVSWQTLVYMIGEVQYGGRVTDD 4357
            :||||:|||||||||||.||::|...|::.:|..::|.|.   :.::.:.|:.||..||||||||
Human  3523 LVQERKKFGPLGWNIPYGFNESDLRISIRQLQLFINEYDT---IPFEAISYLTGECNYGGRVTDD 3584

  Fly  4358 FDKRLLTTFTSVWFCEPLLSNSFEFYK-----GYKVPGTKSLQGFIDYINSLPAYDTPEVFGLHS 4417
            :|:|||.|..:.::...::.|  ..||     .|..|...:.:.:|::|..||....||:||||.
Human  3585 WDRRLLLTMLADFYNLYIVEN--PHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHE 3647

  Fly  4418 NADITYQINSAKGILDTILSVQPKEGG----GGGGETRESIVYQLADDMLRKLPAQYN------A 4472
            |.||:..:...|.:.:::|..|   ||    |..|.| :.|:.::..|:|.|||:.::      .
Human  3648 NVDISKDLQQTKTLFESLLLTQ---GGSKQTGASGST-DQILLEITKDILNKLPSDFDIEMALRK 3708

  Fly  4473 YEVRENLTRMGILLPMNIFLRQEIDRMQRVIKRVHTCLCDLKLAIDGTIVMSPALKESLDAMYDA 4537
            |.||...:       ||..|.||::|...:|..:...|.||:.||.|.:||..||:....::...
Human  3709 YPVRYEES-------MNTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVG 3766

  Fly  4538 RIPETWMKISWES-TTLGFWYTELLERNGQFRTWISTDRPKVFWMTGFFNPQGFLTAMRQEVTRA 4601
            ::||.|.|.|:.| ..||.:.|:.|.|....:.|.::.:|.|||::|||..|.|||...|...|.
Human  3767 KVPEIWAKRSYPSLKPLGSYITDFLARLNFLQDWYNSGKPCVFWLSGFFFTQAFLTGAMQNYARK 3831

  Fly  4602 HKGWALDSVVLQNQITRYNKEDITEYPTEGVYVHGLFLEGASLDRRSGKLIESKMKVLYEQMPVI 4666
            :. ..:|.:..:.::...:..|.:  |.:|||:|||:|:||..||.||.|.|...|:|::.||:|
Human  3832 YT-TPIDLLGYEFEVIPSDTSDTS--PEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPII 3893

  Fly  4667 YIYAINTTAGKDPKLYECPIYRKPQRT--------DLKYVGSIDFETEFNPKHWTLRGVALLCDI 4723
            :|.....:.......|.||:|:..:|.        ...:|.::..:|:...:||..|||||||.:
Human  3894 WIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLCQL 3958

Fly 4724 4723
Human 3959 3958

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9492	NP_001287256.1	DHC_N1	283..843	CDD:285571
		DYN1	1178..4372	CDD:227570	1075/3387 (32%)
		DHC_N2	1458..1861	CDD:285579	123/448 (27%)
		P-loop_NTPase	1994..2222	CDD:304359	129/227 (57%)
		P-loop_NTPase	2309..2444	CDD:304359	56/141 (40%)
		P-loop_NTPase	2662..2926	CDD:304359	88/264 (33%)
		P-loop_NTPase	3025..3287	CDD:304359	100/261 (38%)
		MT	3300..3646	CDD:289543	106/356 (30%)
		AAA_9	3674..3890	CDD:289547	87/216 (40%)
		Dynein_heavy	4031..4713	CDD:281078	231/716 (32%)
DNAH12	NP_001352957.1	SMC_N	<591..>752	CDD:330553	35/188 (19%)
		DHC_N2	683..1110	CDD:312039	122/440 (28%)
		MT	891..3605	CDD:330758	965/2826 (34%)
		AAA_9	2896..3112	CDD:315453	87/216 (40%)
		Dynein_heavy	3255..3955	CDD:308587	234/719 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.710