DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9492 and DNAH9

DIOPT Version :9

Sequence 1:	NP_001287256.1	Gene:	CG9492 / 41171	FlyBaseID:	FBgn0037726	Length:	4724	Species:	Drosophila melanogaster
Sequence 2:	XP_011522005.1	Gene:	DNAH9 / 1770	HGNCID:	2953	Length:	4501	Species:	Homo sapiens

Alignment Length:	4777	Identity:	1390/4777 - (29%)
Similarity:	2302/4777 - (48%)	Gaps:	500/4777 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 DDPEPTPVPDPNKPGPSRSGVASSSSKTPQGGASPSGMPPPKHKKLFLTDGWTCAFTGVCIYIFR 170
            :.|.|..|.   :|||....:.......|:.|.:.:       |.||.
Human    66 EGPRPLLVV---RPGPRGLAIRPGLEVGPESGLAGA-------KALFF----------------- 103

  Fly   171 VNTSKQLP-EEGFQKDLYCGVIDAKNIGLVTSIERIVEFVFMQALAFPSLEGDEEDVSCGLIKGQ 234
            :.|..:.| .:.|:..:.||.:.|      ..:|.:                      ..|....
Human   104 LRTGPEPPGPDSFRGAVVCGDLPA------APLEHL----------------------AALFSEV 140

  Fly   235 LLPGLRSFCSALR----VCEQVCDH-HNVFAD------------------GCDMFEKIDAVEEVK 276
            :||.|.:..:.|.    :||.|..| |::..|                  |.:..|..|:..|..
Human   141 VLPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKTLLPLPAGSEKMEFADSKSETV 205

  Fly   277 DMSKNQEFCAQLEERVNNWTKGILKIL-GESEQLRKENDHSGPQDELEYWKKRGAQFSQLLAHLQ 340
            ..|.::.....:|..|..|:..:..:| .||.|...:.::..|:.|||:||.|......:...|:
Human   206 LDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKSRYEDLKYIYNQLR 270

  Fly   341 DKEVQFTLHCLFLAGSRIIKQWKETDRKITFCYNEARDNSKFIQAMETCCHSLYLDDPVSMKESI 405
            ...|:.....|....|.....:|...|.:.....||:|....:..::....:|...:...:|..:
Human   271 TITVRGMAKLLDKLQSSYFPAFKAMYRDVVAALAEAQDIHVHLIPLQRHLEALENAEFPEVKPQL 335

  Fly   406 LSLLQTVRLIYSVSQFYNTSERTSALMVKITNQMIETCKSYIT-----------CRCKETIWSQD 459
            ..||..|.||::..:.|.:..|.:.|:.:|.|.:|:...:|::           .:.|..:.|..
Human   336 RPLLHVVCLIWATCKSYRSPGRLTVLLQEICNLLIQQASNYLSPEDLLRSEVEESQRKLQVVSDT 400

  Fly   460 RNVIRTKLSNCIKLNHIYHETYYTVREQPFLPNQTPFGFSENFVFGKFDTFCERLSKIISMFNLI 524
            .:..:.:..:..:..|.|.:....|:|         :.|..:.||.:.|.|..:|..:..:....
Human   401 LSFFKQEFQDRRENLHTYFKENQEVKE---------WDFQSSLVFVRLDGFLGQLHVVEGLLKTA 456

  Fly   525 DDYNHLFERRLEGL---LLGEALEDASNHFEEAKKEVTSRKYDYLDHRNSDFNIDFERFIHKTNS 586
            .|::.|.:....|:   .|.:.::.....|:|..:.::....|.|..:::||..|...|..|...
Human   457 LDFHKLGKVEFSGVRGNALSQQVQQMHEEFQEMYRLLSGSSSDCLYLQSTDFENDVSEFNQKVED 521

  Fly   587 LKDTIATLIEKDFDTVWETPQCIRFLVRFEKVSEKIPLTRMD--EKYTRILRYVEKEVDRILKTF 649
            |...:.|:..:.||.........:.|.....:.|: ||...|  :||..:::...|::|.:...:
Human   522 LDRRLGTIFIQAFDDAPGLEHAFKLLDIAGNLLER-PLVARDTSDKYLVLIQMFNKDLDAVRMIY 585

  Fly   650 RKQRDD------PPLARNFPPIAGRIHWCRALSLHITELMD--AVMEHVVLSSLPMAKDLDVRYH 706
            .:...:      .|:.:|.|.:||.:.|.:.|...|.....  ..:.|..:.|.. .|.:..:|.
Human   586 SQHVQEEAELGFSPVHKNMPTVAGGLRWAQELRQRIQGPFSNFGRITHPCMESAE-GKRMQQKYE 649

  Fly   707 NVLGILQEYEDEIVSIWLDQDVSVADACLLQPLLSLQGD--KLFVNLHPTIPLLIREAKMLAKLD 769
            ::|.:|::||..:...|.......:...|.||||....:  ::.:|.:|.:..:::|...|...:
Human   650 DMLSLLEKYETRLYEDWCRTVSEKSQYNLSQPLLKRDPETKEITINFNPQLISVLKEMSYLEPRE 714

  Fly   770 IE-LPIVAATLMSRQQYFITIQDSLNCLIKMFLSTVRAVKLEVR-PLFLPQLVRLTAMLKPGLHT 832
            :: :|..||.:.|.:.::..:..:|..:...:...::.: |||. ||...:|..:...|:....|
Human   715 MKHMPETAAAMFSSRDFYRQLVANLELMANWYNKVMKTL-LEVEFPLVEEELQNIDLRLRAAEET 778

  Fly   833 INWTNQNWTEFYERCKQAIESFDVLVARVHDIYSNRILHVLMWMQDVSLQILPADDEIWTVDEFL 897
            :||..:...::......:|...:..:.:..|....        :|::.        :.|....|
Human   779 LNWKTEGICDYVTEITSSIHDLEQRIQKTKDNVEE--------IQNIM--------KTWVTPIF- 826

  Fly   898 ERSEEACRKAAIELNRKSQMVSEAVEEVLSLVDRATAAFKEIAGDDVITLFDAATPKGDNSGSGG 962
             ::::..|::.:.|:.:    .:.:|:..:|:..:......:..:: :.||
Human   827 -KTKDGKRESLLSLDDR----HDRMEKYYNLIKESGLKIHALVQEN-LGLF-------------- 871

  Fly   963 RKPEDGGGGGGGAAAPSTSGGGGGGQQQDWSILWSCFENPLS-------LLSTTESLPKGMQDMV 1020
                        :|.|:::             :|..:.|.:.       .|:...||...:::..
Human   872 ------------SADPTSN-------------IWKTYVNSIDNLLLNGFFLAIECSLKYLLENTE 911

  Fly  1021 CNAVVEMRRYYSRKVIDVLIKVIRAALDTLRRRFIADENETVFKKPVFALHAQLQIPHVVIKPNL 1085
            |.|.:                                       .|:|.....|.||.:|..|:|
Human   912 CKAGL---------------------------------------TPIFEAQLSLAIPELVFYPSL 937

  Fly  1086 D--------ELQDILVTAGKNITGIAKGVAQWSSGKDPPQVSMTVQPRVGRNHNESTGGGKSRRR 1142
            :        ::.:.|:|:...|..:.            |::|    |:.|..|.:....|
Human   938 ESGVKGGFCDIVEGLITSIFRIPSLV------------PRLS----PQNGSPHYQVDLDG----- 981

  Fly  1143 KIYCLASEERPQMPHMLKSF--------------YSAIMDNKEVAKAVNQLASCTKNVKP-EIQT 1192
             |..||:..|..|..:.:..              |..:.|.|||   :.|.......:.| ||:.
Human   982 -IPDLANMRRTLMERVQRMMGLCCGYQSTFSQYSYLYVEDRKEV---LGQFLLYGHILTPEEIED 1042

  Fly  1193 YIKRWKPYHFLWKNDRTTRQLMEFGLQ--EFETTLRCLSDLDANLLVEPDMEVFGQCVAVYNEKL 1255
            :::...|        .....|.:|.:|  .:||....:..|      || ::||...:.:.....
Human  1043 HVEDGIP--------ENPPLLSQFKVQIDSYETLYEEVCRL------EP-IKVFDGWMKIDIRPF 1092

  Fly  1256 KYGLAIEIKSCNHKIGQAMKKKYKKEMDYVYAVINEMDRKLDRPIR--DLDDVRMIMETLGKIRE 1318
            |..|...||..:....|.:.......:..:.|.|.:.:..|.:.:.  |...:..||..|..::|
Human  1093 KASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKSESGLLKKVEKGDFQGLVEIMGHLMAVKE 1157

  Fly  1319 QEVDMELRIDPIEEAFNVLTRYEVQVEREQFDLVDNLRATFQNLLAGALQAQVKLLDMQPAFQDD 1383
            ::.:.:...:|:::...:|..||.::....|..::.|...:.|:...|:..:.::..:|......
Human  1158 RQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNNIKKVAITVKQQVAPLQANEVTL 1222

  Fly  1384 LRTNLDNFKQDKISYVTEYRTAGPMQ-AGLTPREASD-RLILFQNRFEGMWRRLQTYQSGEELFG 1446
            ||.....|..::..:..::....|.: ..:.|.:..| |.|..|.    |...:.:......||.
Human  1223 LRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDARHIEIQQ----MESTMASISESASLFE 1283

  Fly  1447 LPQTDYPELGQIRKELNLLQKLYKLYNDVIDRVSSYYDIPWNEVDIEEINNELMEFQNRCRKLPK 1511
            :...||.:|.|.|||:..|::|:.....|...:.::...||..:::|.:..|..:|....|.|.|
Human  1284 VNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNLDK 1348

  Fly  1512 GLKEWPAFHALKKTIDDFNDMCPLLEL--MANKAMKPRHWQRIMDVTRYIFEFDSEGFSLKNILE 1574
            .::.|.||..|:.|:  :|.:..|..:  :.|.|::.|||:::|..|...|..|.: .:|.::|:
Human  1349 EVRAWDAFTGLESTV--WNTLSSLRAVAELQNPAIRERHWRQLMQATGVSFTMDQD-TTLAHLLQ 1410

  Fly  1575 APLLKHKEDIEDICISAMKEKDIEAKLKQVTNEWSVHELQFMSFNNRGELLLRGDTTAETIGQLE 1639
            ..|..:::::..|...|.||..:|..||::...|:..|.|:.........||..|  .:.|..||
Human  1411 LQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRTNVPLLCSD--EDLIEVLE 1473

  Fly  1640 DSLMVLGSLLSNRYNAPFRKQIQQWVYDLSNSNEILERWLLVQNMWVYLEAVFVGG-DIAKQLPK 1703
            |:.:.|.:|:.::|.|.|.:::..|...||..:.::..|..||..|.:||::|.|. ||..|||:
Human  1474 DNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQ 1538

  Fly  1704 EAKRFSKIDKSWQKIMQRAHETPGVVACCVGDDLLKQLLPHLQEQLEICQKSLSGYLERKRMMFP 1768
            ::|||..||..::::...|.:.|.||.......|.:: |..:|.:|.:|:|:|:.||:.||:.||
Human  1539 DSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEK-LEDIQGRLCLCEKALAEYLDTKRLAFP 1602

  Fly  1769 RFFFVSDPALLEILGQASDSHTIQNHLLNIFDNTKSVKFH---DVEYNK-MMAIISSEGEMIQLD 1829
            ||:|:|...||:||...:....:|.||..:|||...::|.   ..|..| .:.:.|.|.|.:...
Human  1603 RFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFS 1667

  Fly  1830 RAIRAEGSVETWLTQLLVTAQASL-HSIIRTAYATINDPNFTLLSFLEKAPAQIGLLGIQMVWTR 1893
            ......|.||.||..:|...:|:: |.:.....|....|.   ..:|...|||:.|...|:.||.
Human  1668 EPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKPR---EQWLFDHPAQVALTCTQIWWTT 1729

  Fly  1894 DAEMALMRGRE--RKVMMETNNKFLEMLNTLIDQTTRNLTKRERTNFETLITIHVHQRDIFDILC 1956
            :..||..|..|  ...|.:...|.:..|.|||......|:|.:|....|:.||.||.||:...:.
Human  1730 EVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMI 1794

  Fly  1957 RMNIKSANDFEWLKQCRFYFKEDLDKTWISVTDVTFTYQNEYLGCTDRLVITPLTDRCYITLAQA 2021
            ...:.:|..|.||.|.|..:.:::...:.::.|..|.|..||||.|.|||||||||||||||.|:
Human  1795 AQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQS 1859

  Fly  2022 LTLSMGGAPCGPAGTGKTETVKDMGKTLAKYVVVFNCSDQMDYRGLGRIYKGLAQSGSWGCFDEF 2086
            |.|:|.|||.||||||||||.||:|:.|...|.|||||:||||:..|.|||||||:|:|||||||
Human  1860 LHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEF 1924

  Fly  2087 NRIELPVLSVAAQQVAVVLTAKKEKRKTFLFTDGDTIEMNPEFGIFITMNPGYAGRKELPENLKI 2151
            |||.:.||||.|.||..:..|.::|::.|.|. |:.|.:||..|||||||||||||.|||||||.
Human  1925 NRISVEVLSVVAVQVKSIQDAIRDKKQWFSFL-GEEISLNPSVGIFITMNPGYAGRTELPENLKS 1988

  Fly  2152 QFRTVAMMVPDRQIIIRVKLASCGFLENITLARKFYTLYKLCEEQLTKQVHYDFGLRNILSVLRT 2216
            .||..||:|||.::|..:.|.:.||:|..:|||||.|||:||:|.|:||.|||:|||.|.|||..
Human  1989 LFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVV 2053

  Fly  2217 LGAAKRRNSKDTESTIVMRVLRDMNLSKLIDDDEPLFMSLVSDLFPNQTLEKTNYPELEAAILQQ 2281
            .|:.||.:....|..::||.|||.|:.|::.||.|:||.|:.||||...:.:...|..||.:.:.
Human  2054 AGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRKA 2118

  Fly  2282 TDEASLVYHPPWVLKLIQLYETQHVRHGIMTLGPSGAGKTTCIHTLMKAMTQMGDNHREMRMNPK 2346
            ..:..|.....:|||::||.|...|||.:..:|.:|.||:..:.:|.|....|........:|||
Human  2119 IVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKRRPVWTDLNPK 2183

  Fly  2347 AITAAQMFGRLDVATNDWTDGIFSALWRKTLKLKAGEHVWLVLDGPVDSIWIENLNSVLDDNKTL 2411
            |:|..::||.::.||.:|.||:||::.|:...:......|::|||.:|.:|||:||:|:||||.|
Human  2184 AVTNDELFGIINPATGEWKDGLFSSIMRELANITHDGPKWILLDGDIDPMWIESLNTVMDDNKVL 2248

  Fly  2412 TLANGDRLTMAPTVKIIFEPHNIDNASPATVSRNGMVYMSSSGLDSRPIVQAWLKNR-APGEKST 2475
            |||:.:|:.:.||:|::||..::..|:||||||.|::|::.:.|...|.|.:|::.| ...|::.
Human  2249 TLASNERIPLNPTMKLLFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKREIQTERAN 2313

  Fly  2476 FSDLFDQTFVEVYNWGVQMVKLQMPVLQCNIVQQMLFILEGLIPVKKEDEQAVSMSSKESHDANK 2540
            .:.|||:......:......|..:|:.:.::||.:..:||.|:
Human  2314 LTILFDKYLPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLL---------------------- 2356

  Fly  2541 RLEHQKHVEEARRQSIGSQIVEDLPPETSIEEKEDTCTPEHLHRLYIFALAWGLGGYLSTSD--- 2602
                               ..||:|.:         |..|.....::||..|..||.:....
Human  2357 -------------------TTEDIPAD---------CPKEIYEHYFVFAAIWAFGGAMVQDQLVD 2393

  Fly  2603 -RQRMNLFVKESFPQLDYPKGSAHENTIFDFFVSP-AGVWQSWKTLVTPYMY-PELSTPDYLSIL 2664
             |...:.:....|..:.:|.    :.||||:::.| ...::.|..||..:.: ||:...   :.|
Human  2394 YRAEFSKWWLTEFKTVKFPS----QGTIFDYYIDPETKKFEPWSKLVPQFEFDPEMPLQ---ACL 2451

  Fly  2665 VPIVDNVRIDYLIGTIANQERAVMVIGEQGTGKTVIMKNFMKKMNVESYMGRSFNFSSATSPYQF 2729
            |...:.:|:.|.:..:..::|.||::|..||||:|::...:..::.|:|:.::..|:..|:....
Human  2452 VHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAML 2516

  Fly  2730 QRTIESYVEKRVGVTFGPPGGRKLIVFIDDINLPEINEWGDQITNEIVRQSMDMKGFYSLEKPGD 2794
            |..:|..:||:.|..:||||.:|||.||||:|:||::.:|....:.|:||.:|...:|...|. .
Human  2517 QAVLEKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKL-S 2580

  Fly  2795 FTTIVDVQYVAAMGLPGGGRNDIPSRLKRQFCVFNCNIPDNDSIDKIFRVIGEGHYNAKRG-FVP 2858
            ...|.:||||:.|. |..|...|..||:|.|.||..:.|..|::..|:.:|...|  .|.| |..
Human  2581 LKEITNVQYVSCMN-PTAGSFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQH--LKLGNFPA 2642

  Fly  2859 EIRSLVKKLIVVTRHLWQRTREKLLPTPAKFHYVFSLRDLSRIWQGMVGTLSTVITSESVLMALW 2923
            .::..:..||.:.....|:.....|||..||||:|:|||.:.|:||::.:....:.|...|:.|:
Human  2643 SLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLY 2707

  Fly  2924 KHECTRVFADRFTTFQDKEWFG---SELACLVREELGDSHSQMILPNPVFVDFMRDAPEPTGEEG 2985
            .||..||:.|:....:|.:.|.   :|:.....:::.|...|...|| ::..|.....||.
Human  2708 LHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPN-LYCHFANGIGEPK---- 2767

  Fly  2986 EDTDMELPKVYEPVHSHEVLRERLVMFLAQFNEMVRGSGMDLVFFPDAMLHLVKISRIIRHPRGS 3050
                      |.||.|.|:|.:.||..|...||:  .:.||||.|.|||.|:..|:||:..|||:
Human  2768 ----------YMPVQSWELLTQTLVEALENHNEV--NTVMDLVLFEDAMRHVCHINRILESPRGN 2820

  Fly  3051 VMLVGVGGSGKQSLTKLASFIAGYKTFQIALTRSYNVANFLEDLKLLYRTCGVQGKGTTFLFTDM 3115
            .:|||||||||||||:||:||:....|||.|.:.|.:.:|..||..|....||:...|.||.||.
Human  2821 ALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDA 2885

  Fly  3116 DIKEEGFLEYLNNILSSGVISNLFSRDEQAEIVQELTPVMKRENQRKTATPESVMDFFLARTCTN 3180
            .:.:|.||..:|::|:||.|.:|:|.||...|:..:...:|  :|......|:...||:.|....
Human  2886 QVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVK--SQGLVDNRENCWKFFIDRIRRQ 2948

  Fly  3181 LHVAFCFSPVGETFRSRVQRFPALVSGCTIDWLHPWPKDALVSVARHFLSHFE-IECTPAVKEEL 3244
            |.|..||||||...|.|.::|||:|:...|.|.|.||:.||.||:..||.:.| ||  |.||:.:
Human  2949 LKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIE--PTVKQSI 3011

  Fly  3245 VNALGSIQDIVAETSQEYFQRFRRATHVTPKSYLNFIAGYKNIYQMKQQELRDGVEKMDTGLEKL 3309
            ...:..:...|.:|||.|....:|..:.||||:|.||..|:::....::||:...|:::.||.||
Human  3012 SKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKL 3076

  Fly  3310 KEASASVEILKKDLVVMEEELVEASKNAESVLVEVT---------ERAMQAEIVKNQVLIVKDKA 3365
            ...||.|:.||..|...|.||.:.:::|:. |::|.         |:||..|..:...:|:.:..
Human  3077 HSTSAQVDDLKAKLAAQEVELKQKNEDADK-LIQVVGVETDKVSREKAMADEEEQKVAVIMLEVK 3140

  Fly  3366 EALVACIAHEKALAEEKLEAAKPALEEAENALNTIKPAHIATVRKLGRPPHLIMRIMDCVLILFK 3430
            :....|        ||.|..|:|||..|:.||||:...::..::..|.||..:..:...|::|.
Human  3141 QKQKDC--------EEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLM- 3196

  Fly  3431 RKLHPCIPDAGTPCPKPSWQESLKMMASAT-FLLQLQNYPKDTINDEMIDLLQPYFRMEDYNMDM 3494
                  .|....|..: ||:.:...||... ||..|.|:.|:.|::..:..::||.:..::|.:.
Human  3197 ------APRGRVPKDR-SWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQDPEFNPEF 3254

  Fly  3495 ARRVCGDVAGLLSWTKAMSFFHSVNKEVLPLKANLTMQEARLKLAMDDLAGAEEQLREREEALQA 3559
            ........|||.||...:..|:.|..:|.|.:..|....|.|..|.:.||..:.::....|.|..
Human  3255 VATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHLNENLAK 3319

  Fly  3560 VKDQYDKAVGEKQRLTDAANVCLRKMTAATALINGLSDEKHRWTNQSKEFKIQLGKLVGDVLLAT 3624
            :..:::||..:|.:....|.|....::.|..|:.||:.|..||.:..:.||.|...|.||:||.|
Human  3320 LTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQQERTLCGDILLIT 3384

  Fly  3625 GFLSYCGPYNQEFRANLI-KTWMGILKQKN--IPFTTGLNIINMLVDSSTVSEWTLQGLPNDELS 3686
            .|:||.|.:.:::|.:|: :||...|.|..  ||.|..|:.:.||:|.:.|:.|..:|||.|.:|
Human  3385 AFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPALDPLRMLMDDADVAAWQNEGLPADRMS 3449

  Fly  3687 VQNALIATKSSSYPLLVDPQTQGKIWIKCK--EDRNELQITSLNHKYFRTHLEDSLSLGRPLLIE 3749
            |:||.|......:||:||||.||..|||.|  ||   |::|.:..|.:...:|.:|..|..:|||
Human  3450 VENATILINCERWPLMVDPQLQGIKWIKNKYGED---LRVTQIGQKGYLQIIEQALEAGAVVLIE 3511

  Fly  3750 DVGIDLDPVIDNVLEKNFIKSGSIEKVLVGDKECDVMPGFMLYITTKLPNPAFSPEVSAKTSIID 3814
            ::...:|||:..:|.:..||.|...|  :|||||:..|.|.|.:.|||.||.:.||:.|:.::|:
Human  3512 NLEESIDPVLGPLLGREVIKKGRFIK--IGDKECEYNPKFRLILHTKLANPHYQPELQAQATLIN 3574

  Fly  3815 FTVTMRGLEDQLLGRVILMEKSDLEAERVALFETVMQN--QRNMKELEANLLLRLSSSQGSLVDD 3877
            ||||..|||||||..|:.||:.|||..:..|  |..||  :..:|.||.:||.||||:.|:.:.:
Human  3575 FTVTRDGLEDQLLAAVVSMERPDLEQLKSDL--TKQQNGFKITLKTLEDSLLSRLSSASGNFLGE 3637

  Fly  3878 EALIEVLRVTKTTAEEVNQKLKISEVTERKIMKAREEFRAVAKRGSILYFLIVEMSNVNAMYQNS 3942
            ..|:|.|.:||.||.||.:|::.::|||.||.:|||.:|..|.|.|:|||::.::|.::.|||.|
Human  3638 TVLVENLEITKQTAAEVEKKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFS 3702

  Fly  3943 LKQFLVIFNHSITKSTKSSVTEERINIILRYLTYEVYKFTNRSLYERHKQLFTLMLAIKIDYHNG 4007
            ||.|.::|..::.::.......||:..::..:|:.||::|.|.|:|..|..:...|..:|...|.
Human  3703 LKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNR 3767

  Fly  4008 NISHEEFLTFIKGGASLDLNAVTPKPFRWILDITWLNLVEISKLETFSTVLQVIELNEKDWRCWY 4072
            .::..|....::.    .:...|..|..::....|..:..:|.:|.||.:.:.||.:.|.|:.:.
Human  3768 EVNAVELDFLLRS----PVQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFV 3828

  Fly  4073 ECEKPENEEIPCGYNAILDGFRKLLLIRSWCPDRTISQAKKYIEESLGPEYSEMQILDLEEMWLE 4137
            |.|.||.|::|..:.. ....::|.::|:..|||.....:.::||.||.:|...:.||....:.|
Human  3829 ESECPEKEKLPQEWKN-KTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEE 3892

  Fly  4138 SEPRTPFVCLLSIGSDPTTQIGALAKQKSIVLK-----SVSMGQGQEYHARKMIIESMAIGGWVL 4197
            |.|.||...:||.|.||...:.:..::......     :||:|||||..|...:..:...|.||:
Human  3893 SGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVI 3957

  Fly  4198 LQNVHLSLPFCSEIIDMLVE-SEHIDDSFRMWVTTEP-----HNEFPIGLLQMALKFTNEPPQGI 4256
            |||:||...:.|.:...|.| ||:....||::::.||     .:..|.|:|:.::|.|||||.|:
Human  3958 LQNIHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGM 4022

  Fly  4257 RASLKRSYQSFTQDFLDYTS-ATQWPPLLYTVAFLHTIVQERRKFGPLGWNIPYEFNQADFAASV 4320
            .|:|.::..:||||.|:..| .|::..:|:.:.:.|.:|.|||||||.|||..|.||..|...||
Human  4023 HANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISV 4087

  Fly  4321 QFIQNHLDEMDPKKGVSWQTLVYMIGEVQYGGRVTDDFDKRLLTTFTSVWFCEPLLSNSFEFYKG 4385
            ..:.|.| |.:.|  |.:..|.|:.||:.|||.:|||:|:||..|:...:....:|........|
Human  4088 NVLYNFL-EANAK--VPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPG 4149

  Fly  4386 YKVPGTKSLQGFIDYINSLPAYDTPEVFGLHSNADITYQINSAKGILDTILSVQPKEGGG--GGG 4448
            :.:||.....|:..||::....::|.::|||.||:|.:...:::.:..|:|.:||::...  |.|
Human  4150 FPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAG 4214

  Fly  4449 ETRESIVYQ---------------LADDMLRKLPAQYNAYEVRENLTRMGILLPMNIFLRQEIDR 4498
            .|||..::.               |.:::|.::..::|   :.|.:.::....|..:...||..|
Human  4215 ATREEKLFSWRWHCVLTIQGKVKALLEEILERVTDEFN---IPELMAKVEERTPYIVVAFQECGR 4276

  Fly  4499 MQRVIKRVHTCLCDLKLAIDGTIVMSPALKESLDAMYDARIPETWMKISWESTT-LGFWYTELLE 4562
            |..:.:.:...|.:|:|.:.|.:.|:..::...:|:|...:||:|.:.::.||. |..|:.:||.
Human  4277 MNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLN 4341

  Fly  4563 RNGQFRTWIST-DRPKVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDSVVLQNQITRYNKEDITE 4626
            |..:...|... ..|...|:|||||||.||||:.|...|.:: |.||.:.||..:|:.|:|:...
Human  4342 RIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNE-WPLDQMALQCDMTKKNREEFRS 4405

  Fly  4627 YPTEGVYVHGLFLEGASLDRRSGKLIESKMKVLYEQMPVIYIYAINTTAGKDPKLYECPIYRKPQ 4691
            .|.||.|:||||:|||..|.::|.:.|:|:|.|...|||::|.||.........:|.||:|:..|
Human  4406 PPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQ 4470

  Fly  4692 RTDLKYVGSIDFETEFNPKHWTLRGVALLCDI 4723
            |.. .||.:.:.:|:.||..|.|.|||||..|
Human  4471 RGP-TYVWTFNLKTKENPSKWVLAGVALLLQI 4501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9492	NP_001287256.1	DHC_N1	283..843	CDD:285571	116/588 (20%)
		DYN1	1178..4372	CDD:227570	1078/3251 (33%)
		DHC_N2	1458..1861	CDD:285579	121/410 (30%)
		P-loop_NTPase	1994..2222	CDD:304359	143/227 (63%)
		P-loop_NTPase	2309..2444	CDD:304359	52/134 (39%)
		P-loop_NTPase	2662..2926	CDD:304359	86/264 (33%)
		P-loop_NTPase	3025..3287	CDD:304359	112/262 (43%)
		MT	3300..3646	CDD:289543	100/356 (28%)
		AAA_9	3674..3890	CDD:289547	94/219 (43%)
		Dynein_heavy	4031..4713	CDD:281078	227/712 (32%)
DNAH9	XP_011522005.1	DHC_N1	212..789	CDD:285571	116/588 (20%)
		DHC_N2	1295..1699	CDD:285579	121/409 (30%)
		P-loop_NTPase	1832..2062	CDD:304359	145/230 (63%)
		P-loop_NTPase	2146..2281	CDD:304359	52/134 (39%)
		AAA_7	2439..2710	CDD:289541	88/277 (32%)
		AAA_8	2788..3055	CDD:289546	114/272 (42%)
		MT	3067..3410	CDD:289543	101/359 (28%)
		AAA_9	3438..3650	CDD:289547	94/218 (43%)
		Dynein_heavy	3790..4491	CDD:281078	226/709 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.710