Protein Alignment CG9492 and DNHD1

DIOPT Version :9

• Sequence 1: NP_001287256.1
• Gene: CG9492 / 41171
• FlyBaseID: FBgn0037726
• Length: 4724
• Species: Drosophila melanogaster
• Sequence 2: NP_653267.2
• Gene: DNHD1 / 144132
• HGNCID: 26532
• Length: 4753
• Species: Homo sapiens
• Alignment Length: 4957
• Identity: 971/4957 - (19%)
• Similarity: 1724/4957 - (34%)
• Gaps: 1370/4957 - (27%)

  Fly   671 WCRALSLHITELM--------DAVMEHVV----LSSLP--MAKDLDVRYHNVLGILQEYEDEIVS 721
            |.|.|:|  .||.        ...:|..|    ||.||  :|.|:.|||.:
Human   184 WLRPLTL--PELQRCLGIVGAQVALEEAVWLDGLSLLPLALAADIPVRYES-------------- 232

  Fly   722 IWLDQDVSVADACLLQPLLSLQGDKLFVNLHPTIPLLIREAKMLAKLDIELPIVAA-----TLMS 781
                   |..|...::|:    |.|                :..::||.|:|...|     |..|
Human   233 -------SDTDNAEVEPV----GRK----------------ETRSQLDYEVPREKAFQKSSTGFS 270

  Fly   782 RQQYFITIQDSLNCLIKMFLSTVRAVKLEVRP--LFLPQLVRLTAMLKPGLHTINWTNQNWTEFY 844
            .:..|:..|......::.:|..:..:.|.|.|  .|.|    .:.|:.|. ..:|      .|.|
Human   271 PETSFLDSQVMTALKMERYLKKIHFLYLNVAPSRYFRP----YSLMVVPP-DKVN------PEHY 324

  Fly   845 ERCKQAIESFDVLVARVHDIYSNRIL-------HVLMWMQDVSLQILPADDEIWTVDEF----LE 898
                 ....|.:|  .||.:..:..:       |.::|.|   ||.:|          |    |.
Human   325 -----IFSPFGIL--HVHPVEGSETMTLGTWHHHCVLWQQ---LQFIP----------FFKYCLL 369

  Fly   899 RSEEACRKAAIELNRKSQMVSEAVEEVLSLVDRATAAFKEIAG---------------DDVITLF 948
            |....|.|..:.|....::.......:|..|....|....|:.               |....|.
Human   370 RKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSVSWLPQELDRCYELL 434

  Fly   949 DAATPKGDNSGSGGRKPEDGGGGGGGAAAPSTSGGGGGGQQQDWSILWSCFENPLSLL----STT 1009
            |..|...:......|                              :|..|.....|:|    ..|
Human   435 DLQTALAEEKHKALR------------------------------LLHRCLNLCTSILRLVHEDT 469

  Fly  1010 ESLPKGMQDMV--CNAV------VEMRRYYSR--------------------KVIDVLI-KVIRA 1045
            ..:.:.:|:.|  |:.:      :.::|...:                    :::|.:| :.:.:
Human   470 YHMQQCLQERVQNCDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLIS 534

  Fly  1046 ALDTLRRRFIADENETVFKKP------VFALHAQLQIPHVVIKPNLDELQDILVTAGKNITGIAK 1104
            .|:.....|:|:..:...:||      ||..|.||.  ||   |.::.:...|....:::...|.
Human   535 VLEEQITSFVANILQAPRQKPFLSSQLVFDDHGQLS--HV---PCVENMIQTLTGGLQSVKTSAL 594

  Fly  1105 GVAQ-----------WSSGKDPPQ------------------VSMTVQPRVG-----RNHN---- 1131
            .|.|           :|..:|..:                  ||:...|.||     ::|.
Human   595 QVVQSADLKTSSDSLYSEEEDEEEDSKDEFLMPKFQGQPSDAVSIFCGPNVGLVWPWKSHPIAGI 659

  Fly  1132 -ESTGGGKSRRRKIYCLASEERPQMPHMLKSFYSAIMDNKEVAKAVNQLASCTKNVKPEIQTYIK 1195
             |..|   .|.|..|         .||..|.....:.:|.::.:|:|......:.|..::|.:.:
Human   660 LEVRG---CRLRGQY---------FPHNYKQLEEDLDNNPKIQQALNIQQVLLEGVLCKVQEFCR 712

  Fly  1196 --RWKP--YHFLWKNDRTTRQLMEFG-LQEFETTLRCLSDLDANLLVEPDMEVFGQCVAVYNEKL 1255
              .|..  |.||........:.|..| ::.:.|.:..|:...|.:...| :|:.          .
Human   713 EHHWITGIYEFLQSWGPQKLEDMRGGPIKNYVTLVSRLNVWQARVSSMP-IELL----------T 766

  Fly  1256 KYGLAIEIKSCNHKIGQAMKKKYKK-EMDYVYAVINEMDRKLDRPIRDLDDVRMIMET------- 1312
            |.||.  :.|| |.:...|:.|... ..|.:..|.||......:.:.:|.|...|..|
Human   767 KGGLL--LLSC-HDVQAEMESKLNSIRKDILAHVQNECWNLSQQLMTELTDFMHIFRTINSDIHA 828

  Fly  1313 -------LGKIREQEVDMELRIDPIEEAFNVLTRYEVQV---EREQFDLVDNLRATF-------- 1359
                   |.:..||.|::|.|::.: .|.:.|.|....:   |.|..|:  ::|..|
Human   829 IAQCTQKLNEANEQYVELEERMEYV-RALHELIRNHFSLFSAENEALDI--SVRRQFGESPIPPC 890

  Fly  1360 -----QNLLAGALQAQVKLLDMQPAFQDDLRTNLDNFKQDK------------------ISYVTE 1401
                 .:||...|.|. :||||..|||.: ::....|...|                  :..:..
Human   891 PPPPQPHLLHCPLLAP-QLLDMWEAFQFE-KSQASEFLLSKRHAIMPKLQQLMAAALAELEGLLA 953

  Fly  1402 YRTAGP-MQAGLTPREASDRLILFQNRFEGMWRRLQTYQSGEELFGLPQTDYPELGQIRKELNLL 1465
            ...:|| |......|....:|:..:.:|:.....|........:|...:|..|......:.:...
Human   954 KALSGPFMDPTQDQRSTEHQLVSLERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTRPIVQQ 1018

  Fly  1466 QKLYKLYNDVIDRVSSYYDIPWNEVDIEEINNELMEFQNRCRKLPKGLK-EWPAFHALKKTIDDF 1529
            |:::.||..:.:.:|.:..:.:.:........:...:.....::...|: ..|......:.:.:|
Human  1019 QRIWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELHSPVLQHCMRILGEF 1083

  Fly  1530 NDMCPLLELMANKAMKPRHWQRIMDVTRYIFEFDSEGFSLKNILEAPLLKHKEDIEDICISAMKE 1594
            ....|||..:.:...:..:.|.::...........|..:|..:|..|||:..:.|..:..:..:.
Human  1084 RSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQVWQNENER 1148

  Fly  1595 KDIEAKLKQVTNEWSVHELQFMSF----------------------------NNRGELLLRGDTT 1631
            ...:..::::...|...:|:.::|                            .:.|..:|...:.
Human  1149 IHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVDKDSGTFILSDYSN 1213

  Fly  1632 AETIGQLEDSLMVLGSLLSNRYNAPFRKQIQQWVYDLSNSNEILERWLLVQNMWVYLEAVFVGGD 1696
            .:  ..:::||.||..:|:...:....|...:||..:.....:||.||..|..|::|..|.  .:
Human  1214 LQ--DSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLTFQQKWIFLNKVL--HE 1274

  Fly  1697 IAKQLPKE--AKRFSKIDKSWQKIMQRAHETPGVVACCVGD---------DLLKQLLPHLQEQLE 1750
            :..|.|..  ..||..:|..::.:|:.:...|.|::..|..         ..|:|||.....:||
Human  1275 MKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSPYFQGQQLQQLLQAGSVELE 1339

  Fly  1751 ICQKSLSGYLERKRMMFPRFFFVSDPALLEILGQASDSHTIQNHLLNIFDNTKSVKFHDV---EY 1812
            ....||...|......|||.||:||..|:.:|....:|...|..:...|.:..:|.|...   |.
Human  1340 GIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEAQLWVRRCFPHVHAVSFRSCPTGEK 1404

  Fly  1813 N--------------KMMAIISSEGEMIQLDRAIRAEGSVETWLTQL--------------LVTA 1849
            |              :.:|::.:.||.::|...:.....:..||..|              .|.|
Human  1405 NTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPLHPDLPKWLASLEKCLRLALVHMLQGCVAA 1469

  Fly  1850 QASLHSIIRTAYATINDPNFTLL--------SFLEKAPAQIGLLGIQMVWTRDAEMALMR-GRER 1905
            :.:....:..|...:...|...|        ..::..|.|..|:..::||..:.|.||:. |...
Human  1470 RLARGPSLGEALKQLPKQNKLYLQLYVQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLA 1534

  Fly  1906 KVMMETNNKFLEMLNTLI-----DQTTRNL-TKRERTNFETLITIHVHQRDIFDILCRMNIKSAN 1964
            .|.|....  ||:|...:     .|..::| :.|:.:....|:.:.|..|||..:|.:..:....
Human  1535 MVSMHMRK--LEVLVNFMRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLT 1597

  Fly  1965 DFEWLKQCRFYF-------KEDLD--KT-------------WISVTDVTFTYQNEYLGCTDRLVI 2007
            ||.|::|.:::.       |..|.  ||             ||.|...:|.|..||||  .||..
Human  1598 DFHWVRQLKYHLGSPHIIPKSPLQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLG--PRLGP 1660

  Fly  2008 TP--LTDRCYITLAQALTLSMGGAPCGPAGTGKTETVKDMGKTLAKYVVVFNCSDQMDYRGLGRI 2070
            .|  |.:|..:.|..||.....|...||.|.||...|..:.:.|.:.:|:..||.|::.:.|...
Human  1661 LPSLLPERPALVLLLALEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNY 1725

  Fly  2071 YKGLAQSGSWGCFDEFNRIELPVLSVAAQQVAVV--LTA---KKEKRKTFL------------FT 2118
            ..|..|.|:|...::.:::...:||...|::..:  |.|   ::..|.|..            |.
Human  1726 LNGALQGGAWLLLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFF 1790

  Fly  2119 DGDTIEMNPEFGIFITMNPGYAGRKELPENLKIQFRTVAMMVPDRQIIIRVKLASCGFLENITLA 2183
            :...:.:...:|..:.:.   |....:|.||.:..|.||:.:||.:.:..:.|...|..:...:|
Human  1791 EKHHVSVRLGYGCLLVLR---ALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMA 1852

  Fly  2184 ---RKFYTLYK-------LCEEQLTKQVHYDFGLRNILSVLRTLGAAKR-------RNSKDTEST 2231
               .||::|.:       .|...|.||:..|        .:|||...|.       |:....|..
Human  1853 TRLSKFFSLERELVSGPLPCRLPLLKQILED--------TIRTLNVTKEEPKCQKPRSLAAIEEA 1909

  Fly  2232 IVMR-----VLRDMNLSKLIDDDEPLFMSLVSDLFP--NQTL-EKTNYPELEAAILQQTDEASLV 2288
            .::|     :|..::|..|        ..|:..|||  :|.| |...|..::..::::..:..|.
Human  1910 ALLRSPLFSILNGLHLHNL--------RGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLD 1966

  Fly  2289 YHPPWVLKLIQLYETQHVRHGIMTLGPSGAGKTTCIHTLMK---AMTQMGDNHRE-------MRM 2343
            ..|..:..|.||.:......||:.|||:|:|||||.|:|.|   .:..|.|...:       ..:
Human  1967 PSPDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHL 2031

  Fly  2344 NPKAITAAQMFGRLDVATNDWTDGIFSALWR-----------KTLKLKAGEHVWLVLDGPVDSIW 2397
            .|..::..:..|.|:.:.  |..|||..:.|           :..:...|...|::.||..:..|
Human  2032 YPSGLSPQEFLGWLEGSC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAW 2094

  Fly  2398 IENLNSVLDDNKTLTLANGDRLTMAPTVKIIFEPHNIDNASPATVSRNGMVYMSSSGLDSRPIVQ 2462
            ::::..:|.:...|:|.:|.::...|...::.|..:....||..|....:|:....        |
Human  2095 LDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCGGE--------Q 2151

  Fly  2463 AW------LKNRAPGEKSTFSDLFDQTFVEVYNWGVQMVKLQMPVLQCNIVQQMLFILEGLIPVK 2521
            .|      |....|.|..    |..:|..|:.:....:|...:..|.|..|..:|.:
Human  2152 TWQCILSALMASLPYEYR----LQHRTVAELNHMAEVLVPATLRFLTCQGVSSLLQV-------- 2204

  Fly  2522 KEDEQAVSMSSKE-------SH---DANKRLEHQK-----------HVEEARRQSIG-----SQI 2560
             ..:|||.....|       .|   |.:.||:.:|           .|.::.|.|..     ||:
Human  2205 -HGQQAVCAGVAEVTSMARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRSQV 2268

  Fly  2561 VEDLPPETSIEEKEDTCTPEHLHRL--YIFALAWGLGGYLSTSDRQRMNLFVKESFPQL-DYPK- 2621
            ..|..|        |.|. |||..:  ::|||.||.|.:|.:......:.|:::|..:| :||:
Human  2269 DSDDVP--------DKCR-EHLLAVSSFLFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYPEP 2324

  Fly  2622 -GSAHENTIFDFFVSPAGVWQSWKTLVTPYMYPELSTPDYLSILV--------PIVDNVRIDYLI 2677
             .||   .:||..|||..     .||| |:      |..|||..:        |.:...|:.|::
Human  2325 PPSA---LVFDLHVSPED-----GTLV-PF------TGQYLSSHIKGTLGTFHPSIQTERLLYVV 2374

  Fly  2678 GTIANQERAVMVIGEQGTGKTVIMKNFMKKMNVESYMGRSFNFSSATSPYQFQRTIESYVEKRVG 2742
            ..:.:..:.|::.||..|||:..::..::..:...|......|||:.......|.|:...:.
Human  2375 DLLLSGGQPVLLAGEAATGKSAFVEVLVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQA--- 2436

  Fly  2743 VTFGPPGGR------KLIVFIDDINLPEIN-EWGDQITNEIVRQSMD--MKGFYSLEKPGDFTTI 2798
               .|..|.      .|:..::|::|...: |...|...|.:||:||  :....:||..   |..
Human  2437 ---SPQPGHHQDSKPSLLFLLEDLHLATSDPEKSCQPVLETLRQAMDGTVYAHSTLELQ---TLQ 2495

  Fly  2799 VDVQYVAAMGLPGGGRNDIPSRLKRQFCVFNCNIPDNDSIDKIFR-VIGEGHYNAKRGFV---PE 2859
            ..|.::|.:.:||.....:..||.|.|.|.        :::.:.: .:.|.|....:.::   |.
Human  2496 PTVNFLATVTVPGYCERPLCPRLFRLFTVL--------ALESMTQATLLERHVPIIQAWLERFPS 2552

  Fly  2860 I---RSLVKKLIVVTRHLWQRTREKLLPTPAKFHYVFSLRDLSRIW------------------- 2902
            :   |:|.:.|:..:...|:......:|:|...||.|||..:|.:.
Human  2553 VERERALARGLVRASVEAWEAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYP 2617

  Fly  2903 ---------QGMVGTLSTVITSESVLMALWKHECTRVFADRFTTFQDKEWFGSELACLVR----- 2953
                     .|:.||..||:.:...::.||.||..|.|.||..:.:::.:....|..:.:
Human  2618 NHQEHLRRVSGLRGTCLTVMMATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVFCC 2682

  Fly  2954 ----EELGDSHSQM-------ILPN-------PVFVDFMRDAPEPTGEEGEDTDMELPKVYE--- 2997
                :.||..|.:.       .:|.       ..:.||.....| |.||.|...:::.:|..
Human  2683 GPGPQHLGKDHQESEEEEEEERVPEVESEGELAQWEDFSNSNSE-TEEEEEPYGLQVARVSNSRD 2746

  Fly  2998 --------PVH-------SHEVLRERLVMFLAQFNEMVRGS------------------------ 3023
                    ||.       ||::.:|:... .:.:...||.|
Human  2747 PSLTPSIGPVSRGMKESISHKIRQEKGTR-ASNYRLQVRRSFKTWWQKKPQMDLISPLLLPVLLL 2810

  Fly  3024 -----GMDLVFFPDAML-------------------------------------------HLVKI 3040
                 ..||||..:.:|                                           |:.::
Human  2811 HPQEKPSDLVFSQELILGPNSETPNLYLERQWEKLEEQLATSAAQLKLSPHLARCHSMAQHVARL 2875

  Fly  3041 SRIIRHPR-GSVMLVGVGGSGKQSLTKLASFIAGYKTFQIALTRSYNVANFLEDLKLLYRTCGVQ 3104
            .|::..|| ..::|.|..|:|:.:...|||.|.....|.:.......:...|.|...   ..|:.
Human  2876 VRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQCLRDASW---HAGML 2937

  Fly  3105 GKGTTFLF-TDMDIKEEGFLEYLNNILSSGVISNLFSRDEQAEIVQELTPVMKREN--QRKTATP 3166
            .:....|. :.:|:..   |..|..:.:||.....::..:...|.:.|    .|||  .::....
Human  2938 SQPVALLVPSGVDLTT---LHRLLALATSGSFPGQYTEADLDRIGEHL----PRENLGVKQNIKK 2995

  Fly  3167 ESVMDFFLARTCTNLHVAFCFSPVGETFRSRVQRFPAL-------VSGCTIDWLHPWPKDALVSV 3224
            |.|:..|..:.|::||:.|.   :|:  :...::.|:.       ::..:||...||.:.||..|
Human  2996 EMVLQRFHQQVCSHLHLFFL---IGD--KQAHKQLPSTLFLRLLQLATASIDRYEPWDQAALAKV 3055

  Fly  3225 ARHFL-------------SHFEIECT-PAVKEELVNALGSIQDIVAETSQEYFQRFRRATH-VTP 3274
            |:|.|             .:.:::.: |:|.:.:.        ::..::..|.:....|.. |||
Human  3056 AQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAMA--------LIHLSATHYHEHLCPALPLVTP 3112

  Fly  3275 KSYLNFIAGYKNIYQMKQQELRDGVEKMDTGLEKL----KEASASVEILKKDLVVMEEELVEASK 3335
            |::|:|:..:..:.|....::::..:::...||.|    ||......:    :..:|::|.::.|
Human  3113 KTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGTHANL----IFDLEQQLKDSGK 3173

  Fly  3336 NAESVLVEVTERAMQAEIVKNQVLIVKDKAEALVACIAHEKALAEEKLEAAKPA-LEEAENA--- 3396
            :    |....::..|::::..|.|......|.|:..:|.::    :.|:|.:.| ||:...|
Human  3174 S----LSMFQQQLEQSKLLYKQQLEECRHQENLIENLARQR----DALQAQREAFLEQMSKAFLE 3230

  Fly  3397 -LNTIKPAHIATVRKLGRPPHLIMRIMDCVLILFKRKLHPCIPDAGTPCPKPSWQESLKMMASAT 3460
             |:.::.|....:|....||..::|:.|.:..||..              :..|..:.:::.:..
Human  3231 PLSQLQVADFEEIRSYRAPPESVVRVTDAMCDLFHH--------------ETGWASAKQLLCTED 3281

  Fly  3461 FLLQLQNYPKDTINDEMIDLLQPYFRMEDYNMDMA--RRVCGDVAGLLSWTKAMSFFHSVNKEVL 3523
            |..:|..:||:.|.|.  :|::.:..::...||.|  |.|....|.|.:|..|:..:...:...|
Human  3282 FYQELVFFPKEKITDS--ELIKLHLILKAPGMDDAALRAVSRPAASLAAWLWAVLHYGLAHCRGL 3344

  Fly  3524 P-------LKANLTMQEARLKLAMDDLAGAEEQLREREEALQAVKDQYDKAVGEKQRLTDAANVC 3581
            |       ::|.||.::|||......   |:|.|.......:.|:|            ..|::.|
Human  3345 PTDLLLQQVEATLTREQARLGYYQFQ---AQETLEHNLALAKMVED------------AQASHNC 3394

  Fly  3582 LRK--------------MTAATALINGLSDEKHRWTNQSKEFKIQLGKLVGDVLLATGFLSYCGP 3632
            :.|              |.||      |......||.|.::.|.:...:.||.||.:..:.|.||
Human  3395 VAKTLSQAQCGQYHKWPMKAA------LLTPMRAWTTQLQKLKGRCMTVFGDTLLCSAAIIYLGP 3453

  Fly  3633 YNQEFRANLIKTWMGIL------------------KQKNI-------------PFTTGLNIINML 3666
            :....|..|:..|:.:.                  |||::             ||    :|:::|
Human  3454 FPPLRRQELLDEWLALCRGFQEALGPDDVAQALKRKQKSVSIPPKNPLLATHSPF----SILSLL 3514

  Fly  3667 VDSSTVSEWTLQGLPNDELSVQNALIATKSSSY-----PLLVDPQTQGKIWI------------- 3713
            ...|...:|.....|..:.:....|:....:.|     |||:||..:..||:
Human  3515 SSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLLLDPSNEALIWLDPLPLEENRSFAP 3579

  Fly  3714 ------------------------------------------KCKEDRN---------------- 3720
                                                      |.:|.:|
Human  3580 ALTEGRGKGLMRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEK 3644

  Fly  3721 ----------ELQITSLNH--------KYFRTHLEDSLSLGRPLLIEDVGIDLD-PVIDNVLEKN 3766
                      |.|:.||.:        ....:.|:::.:.|.|:|:.:|.:.|. ..:..:|::.
Human  3645 TESQGSKPAYETQLPSLPYLSVLSGADPELGSQLQEAAACGLPVLLTNVELGLGCEELQWLLQRE 3709

  Fly  3767 FIKSGSIEKVLVGDKECDVMPGFMLYITTKLPNPAFSP----EVSAKTSIIDFTVTMRGLEDQLL 3827
            .:....::            |||.||::|.|...|...    |:....:::|..:.|..||:|:|
Human  3710 QLSPPQVQ------------PGFCLYLSTTLSLCAMEKVLGCELLKGLNVLDLGLNMEILEEQML 3762

  Fly  3828 GRVILMEKSDLE-------------------AERVALFETVMQNQRNMKELEANLLLRLSSSQGS 3873
            ..::..|..:||                   ||...|...:.||.:..|  .|..|..:..:||.
Human  3763 HEILCREYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQNPKRQK--PAKFLRNIVRAQGK 3825

  Fly  3874 LVDDEALIEVLRVTKTTAEEVNQKLKISEVTERKIMKAREEFRAVAKRGSILYFLIVEMSNVNAM 3938
            |....|..|.|.         .|||      :..::.|  .:|.|...|..:...:.::.|:..:
Human  3826 LCQLRAHCEELE---------GQKL------QEMVLWA--PYRPVVWHGMAMVKALSQLQNLLPL 3873

  Fly  3939 YQNSLKQFLVIFNHSITKSTKSSVTEERIN---------IILR-YLTYEVYKFTNRSLYERHKQL 3993
            :..|.:.:|     ::||....|:....||         :.|| :||.::...|..:|......|
Human  3874 FCMSPENWL-----AVTKQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPL 3933

  Fly  3994 FTLMLAIKIDYHNGNISHEEFLTFIKGGASLDLNAVTPKPFRWILDITWLNLVEISKLETFSTVL 4058
            ...:.|:.:....|..|..|.|....|.|: ..:.|..||...:....||..
Human  3934 VGALGALALLQATGKASELERLALWPGLAA-SPSTVHSKPVSDVARPAWLGP------------- 3984

  Fly  4059 QVIELNEKDWRCWYECEKPENEEIPCGYNAILDG-----------------------------FR 4094
                      :.|:|||..|......|..|.|.|                             .:
Human  3985 ----------KAWHECEMLELLPPFVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQ 4039

  Fly  4095 KLLLIRSWCPDRTISQAKKYIEESLGPEYSEMQILDLEEMWLESEPRTPFVCLL------SIGSD 4153
            ||:|.|...|:........:....||....|........ :..|:...|.:.||      |....
Human  4040 KLILWRVLRPECLAGALADFTTSLLGRPLDENTYAPTMP-FKHSQATQPMLILLPPPGHPSATLH 4103

  Fly  4154 PTTQIGALA---KQKSIVLKSVSMGQGQEYHARKMII----ESMAIGGWVLLQNVHLSLPFCSEI 4211
            |.|.|..||   :|....|:.:::| .:.:....:::    ::|..|.|::|.|.||...:..|:
Human  4104 PLTVIQKLAAKYQQGQKQLQVIALG-SEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHWPKEL 4167

  Fly  4212 IDML------------VESEHIDD------------SFRMW--VTTEPHNEFPIGLLQMALK-FT 4249
            :.:|            :|||.:.|            .||:|  |..|.....|..|.|.::. |.
Human  4168 LQLLLELLGRAKVVADLESEQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFW 4232

  Fly  4250 NEPPQGIRASLKRSY-----QSFTQDFLDYTSATQWPPLLYTVAFLHTIVQERRKFGPLGWNIPY 4309
            |:       ||:..:     ....|..|.....||..|||    .||.::..|:.:|.   .:..
Human  4233 NQ-------SLELGHVLIDSVELAQQVLYMQPPTQALPLL----LLHGLLLHRQLYGT---RLQA 4283

  Fly  4310 EFNQADFAASVQFIQNHLDEMDPKKGVSWQTL-------VYMIGEVQYGGRVTDDFDKRLLTTFT 4367
            ...:.......|.:|.. |::       |.:|       ..:...|.|||.:.|..|:..|.:.|
Human  4284 HRGRWSQVTLTQVLQTQ-DQL-------WASLSNPRAAMQELAASVFYGGPLGDTEDREALISLT 4340

  Fly  4368 SV--------WFCEP-----LLSNSFEFYKGYKVPGTKSLQGFID---YINSLPAYDTPEVFGLH 4416
            ..        | .:|     ||:...      .:|..:.|....:   .::.||:...|.:.||.
Human  4341 QACLSPSSGSW-VQPHTPQSLLATLM------PLPELRELDAMAECKAQMHLLPSPPEPRLCGLS 4398

  Fly  4417 SNADITYQINSAKGILDTILSVQP---KEGGGGGGETRESIVYQLADDMLRKLPAQYN--AYEVR 4476
            ...........::.:|..:....|   .|...|.         |||:..||:...|.|  ...::
Human  4399 EGPQAWLLRRQSRALLSALQRSSPVWVPESRRGA---------QLAERRLRQRLVQVNRRLESLQ 4454

  Fly  4477 ENLTRM----------------------GILLPMNIFLRQEIDRMQRVIKRVHTCLCDLKLAIDG 4519
            :.||.:                      |:|....:.|.|.:..:||.:.      |.|:.....
Human  4455 DLLTHVIRQDESDAPWSVLGPNARRPLEGVLETEALELSQLVGTLQRDLD------CLLQQLKGA 4513

  Fly  4520 TIVMSPALKESLDAMYDARIPETWM-------KISWESTTLGFWYTELLERNGQFRTW------- 4570
            ....|........|::..|:|..|.       :..|.      |..: |.|.||....
Human  4514 PPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWH------WLRQ-LSRRGQLLVRYLGVGAD 4571

  Fly  4571 ISTDRP-KVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDSVV-----------LQNQITRYNKED 4623
            .|:|.| :||.::.|.:|:..|.|:|.|.       |||..|           :.:|: :|.:.:
Human  4572 ASSDVPERVFHLSAFRHPRRLLLALRGEA-------ALDQNVPSSNFPGSRGSVSSQL-QYKRLE 4628

  Fly  4624 ITE--------------YPTEGVYVHGLFLEGASLDRRSGKLIESKMKVLYEQMPV-IYIYAINT 4673
            :..              .|..|:.:.||.:..|..|..:|.|.:|.........|| |...|..|
Human  4629 MNSNPLHFRVENGPNPTVPERGLLLIGLQVLHAEWDPIAGALQDSPSSQPSPLPPVSISTQAPGT 4693

  Fly  4674 T---AGKDPKLYECPIY 4687
            :   |..|..:|.||:|
Human  4694 SDLPAPADLTVYSCPVY 4710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9492	NP_001287256.1	DHC_N1	283..843	CDD:285571	40/192 (21%)
		DYN1	1178..4372	CDD:227570	778/3929 (20%)
		DHC_N2	1458..1861	CDD:285579	82/473 (17%)
		P-loop_NTPase	1994..2222	CDD:304359	62/256 (24%)
		P-loop_NTPase	2309..2444	CDD:304359	38/155 (25%)
		P-loop_NTPase	2662..2926	CDD:304359	62/315 (20%)
		P-loop_NTPase	3025..3287	CDD:304359	61/330 (18%)
		MT	3300..3646	CDD:289543	80/377 (21%)
		AAA_9	3674..3890	CDD:289547	57/333 (17%)
		Dynein_heavy	4031..4713	CDD:281078	163/825 (20%)
DNHD1	NP_653267.2	DHC_N2	1019..1467	CDD:285579	80/451 (18%)
		P-loop_NTPase	1649..1867	CDD:304359	54/222 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2688..2766		14/78 (18%)
		P-loop_NTPase	2870..3119	CDD:304359	55/271 (20%)
		MT	<3193..3467	CDD:289543	69/314 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	3580..3657		4/76 (5%)
		AAA_9	<3664..3802	CDD:289547	28/149 (19%)
		Dynein_heavy	3979..4741	CDD:281078	161/816 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	4669..4697		7/27 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900