DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scm and Mbtd1

DIOPT Version :9

Sequence 1:	NP_001247006.1	Gene:	Scm / 41168	FlyBaseID:	FBgn0003334	Length:	877	Species:	Drosophila melanogaster
Sequence 2:	XP_038943608.1	Gene:	Mbtd1 / 688133	RGDID:	1592427	Length:	719	Species:	Rattus norvegicus

Alignment Length:	309	Identity:	98/309 - (31%)
Similarity:	146/309 - (47%)	Gaps:	39/309 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 DAYLEETGSEAAPAKCFKQAQNPPNND--FKIGMKLEALDPRNVTSTCIATVVGVLGSR-LRLRL 239
            |...::.|....|...|.:.:....:.  ||.||||||:||.|:::.|:||:..||... |.:.:
  Rat   382 DITKKQDGHFDTPPHLFAKVKEVDQSGEWFKEGMKLEAIDPLNLSTICVATIRKVLADGFLMIGI 446

  Fly   240 DGS---DSQNDFWRLVDSTEIHAIGHCEKNGGMLQPPLGFRMNASSWPGYLCKILNNAMVAPEEI 301
            |||   |..:.|.....|..|..:|.||.|...|.||.|:......|..||.:  ..::.||.::
  Rat   447 DGSEAADGSDWFCYHATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRE--TGSIAAPVKL 509

  Fly   302 FQPEPPEPEENLFKVGQKLEAVDKKNPQLICCATVDAIKDDQIHVTFDGWRGAFDYWCNYRSRDI 366
            |..:.|   .:.|:||.||||||...|:|||.|||..|....:.:.||||...:|.|.:..|.|:
  Rat   510 FNKDVP---NHGFRVGMKLEAVDLMEPRLICVATVTRIIHRLLRIHFDGWEEEYDQWVDCESPDL 571

  Fly   367 FPAGWCARSCHPMQPPGHKSRMD--SSSSKQR----------CPRPRYTVVAESEAMVPASPATA 419
            :|.|||..:.:.:|||..:|..:  |:||||:          ..:.|...|.:....:.:.|.|
  Rat   572 YPVGWCQLTGYQLQPPASQSSRESQSASSKQKKKAKSQQYKGHKKKRKMPVGKKPVSLSSLPMT- 635

  Fly   420 HFHPNCKGG---PFINNSKLPCMVTGPTYQTL-AKLCLQEVLAASTDTQ 464
                   ||   .|..:.:|    |.|.|:|| |:..|:.....||..:
  Rat   636 -------GGVRRSFSGDEEL----TPPPYRTLPAQTALEAFPPPSTSRE 673

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scm	NP_001247006.1	zf-FCS	55..95	CDD:283998
		MBT	178..273	CDD:214723	33/100 (33%)
		MBT	<312..382	CDD:214723	30/69 (43%)
		DUF3588	418..524	CDD:288954	14/51 (27%)
		SAM_Scm	800..870	CDD:188977
		SAM	806..867	CDD:197735
Mbtd1	XP_038943608.1	MBT	172..272	CDD:214723
		MBT	289..379	CDD:214723
		MBT	386..483	CDD:214723	32/96 (33%)
		MBT	495..587	CDD:214723	36/96 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910