DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scm and SCML1

DIOPT Version :9

Sequence 1:	NP_001247006.1	Gene:	Scm / 41168	FlyBaseID:	FBgn0003334	Length:	877	Species:	Drosophila melanogaster
Sequence 2:	XP_005274635.1	Gene:	SCML1 / 6322	HGNCID:	10580	Length:	330	Species:	Homo sapiens

Alignment Length:	162	Identity:	51/162 - (31%)
Similarity:	77/162 - (47%)	Gaps:	23/162 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   708 VHPEQANVKPSNSYYKSPTTLSSSASLPTSVSTPFTGCQSASSTALAAGGVTAAKAATAPAGAAA 772
            |||...:......||.|                  .|....||:.|..|...|.......:...|
Human   183 VHPSDFSEHNCQPYYAS------------------DGATYGSSSGLCLGNPRADSIHNTYSTDHA 229

  Fly   773 TAGASPSYTAITSPVSTPTSALANSHLRSQPIDWTIEEVIQYIESNDN-SLAVHGDLFRKHEIDG 836
            :| |.||.|  .|||.. ...:....:...|..|::|.|:.:::..|. :|....||||.|||||
Human   230 SA-APPSVT--RSPVEN-DGYIEEGSITKHPSTWSVEAVVLFLKQTDPLALCPLVDLFRSHEIDG 290

  Fly   837 KALLLLNSEMMMKYMGLKLGPALKICNLVNKV 868
            ||||||.|::::|::|:|||.|:|:|..::::
Human   291 KALLLLTSDVLLKHLGVKLGTAVKLCYYIDRL 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scm	NP_001247006.1	zf-FCS	55..95	CDD:283998
		MBT	178..273	CDD:214723
		MBT	<312..382	CDD:214723
		DUF3588	418..524	CDD:288954
		SAM_Scm	800..870	CDD:188977	30/70 (43%)
		SAM	806..867	CDD:197735	29/61 (48%)
SCML1	XP_005274635.1	SAM_Scm	253..324	CDD:188977	30/70 (43%)
SCML1	XP_005274635.1	SAM	256..324	CDD:197735	30/67 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149827
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3766
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12247
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.930