Protein Alignment Scm and l3mbtl1b

DIOPT Version :10

• Sequence 1: NP_731385.1
• Gene: Scm / 41168
• FlyBaseID: FBgn0003334
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: XP_688020.5
• Gene: l3mbtl1b / 559572
• ZFINID: ZDB-GENE-100922-38
• Length: 786
• Species: Danio rerio
• Alignment Length: 998
• Identity: 206/998 - (20%)
• Similarity: 284/998 - (28%)
• Gaps: 455/998 - (45%)

  Fly    23 NATSSASASASSTSTSASPGSTTSPAST--QRQRG-----------------------RPAKRAT 62
            |.||:.:|...|.:..    .|::||||  |||.|                       .|....|
Zfish    80 NTTSNQTAKIQSNTDH----QTSTPASTEPQRQAGGDSSTVDNPIINTVPNAIVPVTEAPINCRT 140

  Fly    63 CTWCGEGKLPLQYVLPTQTGKKEFCSETCIAEFRKAYSKGACTQCDNVIRDGAPNKEFCSIMCMN 127
            |...|..:..||       ||  |||.:|:..     |.|..|          |.:.|.......
Zfish   141 CGLSGSRESFLQ-------GK--FCSASCVQP-----SSGRST----------PAEAFEGERLGK 181

  Fly   128 KHQKKNCSTRHSGGSASGKGLAESERKLLASGAPAP------TGPFQYESFHVFDWDAYLEETGS 186
            :.:||......|..........|.||...:.|..|.      |.|...:.  .:.|..||||..:
Zfish   182 RVRKKKKMFMESEDEEEENIEEEEERVKSSKGRRAAKVARLVTAPLVKKK--TWSWSVYLEEERA 244

  Fly   187 EAAPAKCFKQAQNPP--NNDFKIGMKLEALDPRNVTSTCIATVVGVLGSRLRLRLDGSDSQNDFW 249
            .|||.|.||:.|:.|  .|.||:|||||.|||.:....|:.||..|.|.|:||..||.....|||
Zfish   245 AAAPLKLFKEHQSFPQSRNGFKVGMKLEGLDPCHPALFCVLTVAEVQGYRIRLHFDGYPECYDFW 309

  Fly   250 RLVDSTEIHAIGHCEKNGGMLQPPLGFRMNASSW------------PGYLCKILNNAM------- 295
            ...||.::...|.|||....|..|.|.|....:|            |.:|.|.||.::
Zfish   310 VNADSWDVKPPGWCEKTSLKLLLPKGCRDGEFNWNTYVKNCRGQLAPKHLFKSLNTSVTPSGFRA 374

  Fly   296 ----------------------------------------------------------------- 295
                                                                             
Zfish   375 GMKLEAVDRKNLSDICVATIAAAVDNRLLIHIDHCDDTHDYWCDASSPYIHPVGYCEEVKLTLTT 439

  Fly   296 ----------------------VAPEEIFQPEPPEPEENLFKVGQKLEAVDKKNPQLICCATVDA 338
                                  .||...|:..||..    |:||.|||||||:||.||..||:..
Zfish   440 PAEYKHLKGFSWEKYLEETGTQAAPARAFKQRPPHG----FQVGVKLEAVDKRNPMLIRVATISD 500

  Fly   339 IKDDQIHVTFDGWRGAFDYWCNYRSRDIFPAGWCARSCHPMQ----------PPGHKSRMDSSSS 393
            .::.:|.:.||||...:|||.:..|.::.|.|||.::.||:|          |||
Zfish   501 TEEHRIKIHFDGWSDEYDYWLDADSPELHPVGWCQKTGHPLQHPNGTRDSPVPPG---------- 555

  Fly   394 KQRCPRPRYTVVAESEAMVPASPATAHFHPNCKGGPFINNSKLPCMVTGPTYQT--LAKLCLQEV 456
             |.||.                       |.|.|...|.         ||.|.|  .|..|....
Zfish   556 -QGCPT-----------------------PGCNGVGHIR---------GPRYGTHYTAVSCPYSD 587

  Fly   457 LAASTDTQQLSKLLFALEGDVHIVTAAGKNFTVKIPSPMRMKDDESLAQFIETLCTTCRACANLI 521
            |..:.|.....:|             :|:. .|.|..|.|.:..|:|.|
Zfish   588 LNFNKDGLVPDRL-------------SGER-PVTISGPPRHRRAETLTQ---------------- 622

  Fly   522 SLVHETEECKKCANSRKRQLTQSATPPSSPVLADKRNRQSNSATTSPSEKIIKQELAVKSPVESK 586
                            ..|.|.||:.|..|         ..:....|..:.:::.:...
Zfish   623 ----------------THQPTSSASTPEPP---------DTTTDACPQARPVREHVVTA------ 656

  Fly   587 SKTSTNNGKEPASQQNSNHSLNNNNNSASKSSNKVVIKSEPNGANAQTSSTTQAL----RKVRFQ 647
                                      :|.|......:|.|.:|.::......:::    .:.|||
Zfish   657 --------------------------AAPKCVKAPQVKQEGDGKDSLQQFLHESVFCGWEQPRFQ 695

  Fly   648 HHANTNTNSSATNGNQDTSQTTHVSTSHCSSSSTSSSTSLAGGSANTSTIGKYLAPLVAEVHPEQ 712
                                                                    |..|.|
Zfish   696 --------------------------------------------------------LCWEKH--- 701

  Fly   713 ANVKPSNSYYKSPTTLSSSASLPTSVSTPFTGCQSASSTALAAGGVTAAKAATAPAGAAATAGAS 777
                              ...||.::                  |:||.:.:
Zfish   702 ------------------GKLLPEAL------------------GLTAKRVS------------- 717

  Fly   778 PSYTAITSPVSTPTSALANSHLRSQPIDWTIEEVIQYIESNDNSLAVHGDLFRKHEIDGKALLLL 842
                                       .|..|||..::.... ....|...|||.:|||:|.|||
Zfish   718 ---------------------------KWNTEEVASFVRGLP-GCREHAPTFRKEQIDGEAFLLL 754

  Fly   843 NSEMMMKYMGLKLGPALKICNLV 865
            ....::|.:.:||||||||.|.:
Zfish   755 TQSDIVKILSIKLGPALKIYNSI 777

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scm	NP_731385.1	zf-FCS	58..95	CDD:428958	11/36 (31%)
		MBT_dScm_rpt1	196..294	CDD:439097	42/111 (38%)
		MBT_dScm_rpt2	312..383	CDD:439100	33/80 (41%)
		SLED	418..522	CDD:463469	21/105 (20%)
		SAM_Scm	800..870	CDD:188977	25/66 (38%)
l3mbtl1b	XP_688020.5	MBT	260..360	CDD:459242	36/99 (36%)
		MBT	367..459	CDD:459242	0/91 (0%)
		MBT_L3MBTL1-like_rpt3	472..544	CDD:439093	34/75 (45%)
		zf-C2HC	558..586	CDD:460240	12/59 (20%)
		SAM_Scm-like-3MBT3,4	716..781	CDD:188981	25/103 (24%)