Protein Alignment Scm and scml2

DIOPT Version :10

• Sequence 1: NP_731385.1
• Gene: Scm / 41168
• FlyBaseID: FBgn0003334
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: XP_009304396.1
• Gene: scml2 / 559561
• ZFINID: ZDB-GENE-130530-546
• Length: 723
• Species: Danio rerio
• Alignment Length: 871
• Identity: 283/871 - (32%)
• Similarity: 377/871 - (43%)
• Gaps: 291/871 - (33%)

  Fly   128 KHQKKNCSTRHSGGSASGKGLAESERKLLASGAPAPTGPFQYESFHVFDWDAYLEETGSEAAPAK 192
            ||.|:. |.|::..|...:.|.|:                       |.|:.||.||.|..|...
Zfish    10 KHHKEK-SGRNNEDSQPSQKLTEA-----------------------FSWEMYLRETSSCPASPS 50

  Fly   193 CFKQAQNPPNNDFKIGMKLEALDPRNVTSTCIATVVGVLGSRLRLRLDGSDSQNDFWRLVDSTEI 257
            ||:|::.||.|||::|||:||.||||.:|.|||||:|::|.|||||||||||.||||||||:.:|
Zfish    51 CFRQSRVPPANDFRVGMKVEACDPRNASSWCIATVMGLMGVRLRLRLDGSDSTNDFWRLVDAADI 115

  Fly   258 HAIGHCEKNGGMLQPPLGFRMNASSWPGYLCKILNNAMVAPEEIFQPEPPEPEENLFKVGQKLEA 322
            ..||.|||:|.||||||||||||||||.:|.|.|:.|.:||...|:.|||.|.:|.||.|.||||
Zfish   116 QPIGTCEKSGDMLQPPLGFRMNASSWPMFLLKTLSGAEMAPSSAFKKEPPRPTQNFFKAGMKLEA 180

  Fly   323 VDKKNPQLICCATVDAIKDDQIHVTFDGWRGAFDYWCNYRSRDIFPAGWCARSCHPMQPPGH--- 384
            ||:|||.|||.||:..::.|:|.:.||||||||||||.:.||||||.|||..:.|.:||||:
Zfish   181 VDRKNPYLICPATIGEVRGDKIFIMFDGWRGAFDYWCQFDSRDIFPVGWCQLTNHSLQPPGNCFT 245

  Fly   385 --KSRMDSSS----------SKQRCP---------------RPRYTVVAESEAMVPAS------- 415
              |:.:.|.|          |..|.|               ||:...:|..:|...|:
Zfish   246 IPKTLLPSVSRPSPSWRPMQSPYRLPHPLPPLPVRKGVRGRRPKSQTIAMLKAAAEAAAAGNSPS 310

  Fly   416 ------PATAHFHPNC---------KGGPFINNS---KLPCMVTGP------------TYQT--- 447
                  |.:||..|..         |.||...:.   |:|..::.|            :.||
Zfish   311 QNGQSQPTSAHKSPISSPLTPKPYKKRGPKPGSKRKPKVPHSLSSPILSSSVSDGRLSSLQTTRD 375

  Fly   448 ---LAKLC---------------------------------LQEVLAASTDTQQLSKLLFAL--- 473
               ::.:|                                 ||..:.|..|.....|.||:.
Zfish   376 SGVVSTVCVYVNKHGNSGPHLDRKLLLQLPDHFGPGPVNTVLQHAVQACVDCAFQPKALFSFLQS 440

  Fly   474 ------------EGDVHIV---TAAGKNFTVKIPSPMRMKDDESLAQFIETLCTTCRACANLISL 523
                        ||.:|.|   ||:..:|.::               |:||||...: |.||.|
Zfish   441 QSDGGEIIRVRSEGGIHYVKLPTASSASFVLR---------------FLETLCHHLQ-CDNLFS- 488

  Fly   524 VHETEECKKCANSRKRQLTQSATPPSSPVLADKRNRQSNSATTSPSEKIIKQELAVKSPVESKSK 588
                                  :.|.||:         .|:|.:|.|               :||
Zfish   489 ----------------------SQPFSPL---------TSSTHTPYE---------------RSK 507

  Fly   589 TSTNNGKEPASQQNSNHSLNNNNNSASKS-SNKVVIKSEPNGANAQTSSTTQALRKVRFQHHANT 652
            :......|..|........|.::::.|.: |.|:              ..|:||        .:.
Zfish   508 SVKEETSEALSVARGTRRFNRDSSAYSTALSPKL--------------QRTEAL--------PSD 550

  Fly   653 NTNSSATNGNQDTSQTTHVSTSHCSSSSTSSSTSLA-GGSANTSTIGKYLAPLVAEVHPEQANVK 716
            .|.:.|.||.....|       ....|..|:|.|:| ...|:.||         :|.|....
Zfish   551 ETIAHAENGASTEQQ-------FLEESMDSASKSVAPRPPAHRST---------SEFHTPTG--- 596

  Fly   717 PSNSYYKS-PTTLSSSASLPTSVST--PFTGCQSASSTALAAGGVTAAKAATAPAGAAATAGASP 778
             |:.:|.| |..|...:|.|....|  ...|..|||||             |.|...|..  ..|
Zfish   597 -SSPHYPSHPPLLRGLSSNPAEPRTHRRVEGRLSASST-------------TGPDHQATE--KDP 645

  Fly   779 SYTAITSPVSTPTSALANSHLRSQPIDWTIEEVIQYIESND-NSLAVHGDLFRKHEIDGKALLLL 842
            |.|:..||.|                 |:||||:|::...| .:|..|.:||||||||||||:||
Zfish   646 SKTSNKSPSS-----------------WSIEEVMQFVRDADPQALGPHAELFRKHEIDGKALMLL 693

  Fly   843 NSEMMMKYMGLKLGPALKICNLVNKV 868
            .|:|:|||||||||||||:|:.:.|:
Zfish   694 RSDMIMKYMGLKLGPALKLCHHIEKL 719

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scm	NP_731385.1	zf-FCS	58..95	CDD:428958
		MBT_dScm_rpt1	196..294	CDD:439097	68/97 (70%)
		MBT_dScm_rpt2	312..383	CDD:439100	44/70 (63%)
		SLED	418..522	CDD:463469	34/184 (18%)
		SAM_Scm	800..870	CDD:188977	40/70 (57%)
scml2	XP_009304396.1	MBT	33..162	CDD:459242	82/128 (64%)
		MBT_dScm-like_rpt2	167..241	CDD:439082	45/73 (62%)
		RBR	279..349	CDD:465382	12/69 (17%)
		SLED	381..490	CDD:463469	24/147 (16%)
		SAM_Scm	650..721	CDD:188977	43/87 (49%)