Protein Alignment Scm and Sfmbt2

DIOPT Version :10

• Sequence 1: NP_731385.1
• Gene: Scm / 41168
• FlyBaseID: FBgn0003334
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: NP_001185737.1
• Gene: Sfmbt2 / 353282
• MGIID: 2447794
• Length: 975
• Species: Mus musculus
• Alignment Length: 1037
• Identity: 216/1037 - (20%)
• Similarity: 335/1037 - (32%)
• Gaps: 372/1037 - (35%)

  Fly   126 MNKHQKKNCSTRHSGGSASGKGLAESERKLLASGAPAPTGPFQYESFHV----FDWDAYLEETGS 186
            ::|.:..:.|.....|||:|.|...||                 |..::    |.|..||||||:
Mouse     7 VSKKRNSSSSLEKITGSANGNGTLYSE-----------------EDTNLEENDFSWGDYLEETGT 54

  Fly   187 EAAPAKCFKQAQNPPNNDFKIGMKLEALDPRNVTSTCIATVVGVLGSRLRLRL--DGSDSQNDFW 249
            .|.|...|:..:....::|:.|||||..:..|..:..:||::...|..|.||.  .|.|.:.|||
Mouse    55 RAVPHVSFRHVEISIRSNFQPGMKLEVANKNNPDTYWVATIITTCGQLLLLRYCGYGEDRRADFW 119

  Fly   250 RLVDSTEIHAIGHCEKNGGMLQPPLGFRMNASSWPGYLCKILNNAMVAP---------------- 298
            ..|...::|.:|.|.:|..:|:||...:...|.|..:|.:.|..:..||
Mouse   120 CDVIIADLHPVGWCTQNNKVLRPPDAIKDKYSDWTDFLIRELTGSRTAPANLLEGPLRGKGPIDL 184

  Fly   299 --------------------------------------------------------------EEI 301
                                                                          |..
Mouse   185 ITVDSLIELQDSQNPFQYWIVSVTENVGGRLRLRYVGLEHTESYDRWLFYLDYRLRPIGWCQENK 249

  Fly   302 FQPEPP----------------------------------------------------------- 307
            ::.:||
Mouse   250 YRMDPPSELYYLKLPFEWKCALEKALVLAAESPLPMEVFKDHADLQSHFFTVGMRLETLHISDPF 314

  Fly   308 -----------------------EPE--------------------------------------- 310
                                   .||
Mouse   315 HIYPASVTKVFNSKFFQVAIDDLRPEADKPTMLCHADSLGILPVQWCLKNGVNLAPPKGYSGQDF 379

  Fly   311 -------------------ENLFKVG----QKLEAVDKKNPQLICCATVDAIKDDQIHVTFDGWR 352
                               :|.|..|    .|||||:..||..:|.|||.::|...:.:..:|..
Mouse   380 NWVDYHKQRQAEEAPHFCFKNAFSRGFSKNMKLEAVNPVNPGEVCVATVVSVKGRLLWLHLEGLE 444

  Fly   353 GAF-DYWCNYRSRDIFPAGWCARSCHPMQPPGHKSRMDSSSSKQR-----------CPRPRYTVV 405
            ... |...:..|.||||.|||..:.:|:..| :|:   ||.||::           .|.|...:.
Mouse   445 TPMPDIIVDMDSMDIFPVGWCEANSYPLTTP-YKA---SSKSKRKTVHFKMEKQLLSPVPIEKIP 505

  Fly   406 AESEAMVPA--SPATA----------HFHPNCKGGPFINN---SKLPCMVTGPTYQTLAKLCLQE 455
            .|...:.|.  ||..|          ..:..|..|||:|.   |:||..| ||   .:..|.|:|
Mouse   506 HELCLLPPQMDSPVGAINAKYCCPQLFVNHRCFSGPFLNKGRISELPQSV-GP---GMCVLVLKE 566

  Fly   456 VLAASTD-TQQLSKLLFALE--------GDVHIVTA--AGKNF--TVKIPSPMRMKDDESLAQFI 507
            :|...|: ..:..::|..|:        ....|:.|  .||.:  .|||     ::..:.:..|.
Mouse   567 ILTLITNAAYKPGRVLRELQLVEDPEWNSQEEILKAKYGGKTYRAVVKI-----VRTADQVMNFC 626

  Fly   508 ETLCTTCRACANLIS--LVHET--EECKKCANSR--KRQLTQSATPPSSPVLADKRNRQSNSATT 566
            ..:|.....|.||:|  |:.||  |.|.....:|  ||:...|.:|.|     :.::..::.||.
Mouse   627 RQVCAKLECCPNLLSPVLISETCPENCSVHTKTRYNKREKGSSLSPAS-----ELKDDSASHATK 686

  Fly   567 SPSEKI------------IKQELAVKSPVESKSKTSTNNGKEPASQQNSNHSLNNNNNSASKSSN 619
            ....||            |:..|.| |.:|:..| ||...|...|......          :.|.
Mouse   687 LQKAKIPQTYYYGKRRRVIQSSLRV-SNIETPPK-STRRRKRRKSVYVQKR----------RKSA 739

  Fly   620 KVVIKSEPNGANAQTSSTTQALRKVRFQHHANTNTNSSATNGNQDTSQTTHVSTSHCSSSSTSSS 684
            .||....|.|..|.......|    ........:...|...|         :..|...|...:..
Mouse   740 IVVPAGVPAGVPAGVPEDIPA----GIPEGIPASIPESIPEG---------IPESLPESLPEAIP 791

  Fly   685 TSLAGGSANTSTIGKYLAPLVAEVHPEQANVKPSNSYYKSPT--TLSSSASLPTSVSTPFTGCQS 747
            .|:..|||..:...|          .|..:.....:.|..|.  |.:|:|.:      ||...:.
Mouse   792 ESIPKGSAQKTEQEK----------RETLDTARKKTGYHGPAYQTDTSAAQV------PFARPRR 840

  Fly   748 A-----SSTALAAGGV-TAAKAATAPAGAAATAGASPSYTAITSPVSTPTSALANSHLRSQPIDW 806
            |     :|.||....| .|.:..|.|..|::..........|..|..:..|......|.|.|::|
Mouse   841 AVTLRRNSEALKRPPVERARRVRTVPTTASSNNRVKGPLVRIVKPEDSSQSDEEKLILESNPLEW 905

  Fly   807 TIEEVIQYIESNDNSLAVHGDLFRKHEIDGKALLLLNSEMMMKYMGLKLGPALKICNLVNKV 868
            ::.:|:::|:..|  .|....:|::.:|||:|||||....:.:.|.||||||:|:|:.:.:|
Mouse   906 SVTDVVRFIKLTD--CAPLARIFQEQDIDGQALLLLTLPTVQECMELKLGPAIKLCHQIERV 965

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scm	NP_731385.1	zf-FCS	58..95	CDD:428958
		MBT_dScm_rpt1	196..294	CDD:439097	30/99 (30%)
		MBT_dScm_rpt2	312..383	CDD:439100	26/75 (35%)
		SLED	418..522	CDD:463469	31/129 (24%)
		SAM_Scm	800..870	CDD:188977	26/69 (38%)
Sfmbt2	NP_001185737.1	MBT_SFMBT2_rpt1	70..163	CDD:439102	30/92 (33%)
		MBT	182..279	CDD:459242	3/96 (3%)
		MBT_SFMBT2_rpt3	297..389	CDD:439106	2/91 (2%)
		MBT_SFMBT2_rpt4	405..495	CDD:439108	30/93 (32%)
		SLED	528..643	CDD:463469	31/123 (25%)
		SAM_Scm-like-4MBT1,2	893..975	CDD:188980	27/75 (36%)