Protein Alignment Scm and L3mbtl3

DIOPT Version :10

• Sequence 1: NP_731385.1
• Gene: Scm / 41168
• FlyBaseID: FBgn0003334
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: NP_001419245.1
• Gene: L3mbtl3 / 309550
• RGDID: 1305474
• Length: 868
• Species: Rattus norvegicus
• Alignment Length: 968
• Identity: 239/968 - (24%)
• Similarity: 356/968 - (36%)
• Gaps: 227/968 - (23%)

  Fly     7 SSTSSGSN-------------SAAPGAS--------------TNATSSASA-SASSTSTSASPGS 43
            |||:||..             ...||:.              |:.:...|. .|::|:|...|.:
  Rat     5 SSTTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDESEMESVKKATATTTWMVPTA 69

  Fly    44 TTSPAS--TQRQRGRPAKRATCTWC-----GEGKLPLQYVLPTQTGKKEFCSETCIAEFRKAYSK 101
            ..:|.|  :.|....||...:...|     .:..:|.:....::....:||...|      .|..
  Rat    70 QDAPPSPLSSRPAFPPAYWTSPPGCPTVFSEKTGVPFRLKEQSKVDGLQFCENCC------QYGN 128

  Fly   102 GA--------CTQ-CDNVI--------RDGAPNKEFCSIMCMNKHQKK---------------NC 134
            |.        |:| |....        |||..:.:.....|..|.:.|               ..
  Rat   129 GEECLSGGNYCSQNCSRRARDKDQKEDRDGGEDNDEEDPKCSRKKKPKLSLKADSKEDEERDDEM 193

  Fly   135 STRHSGGSASGKGLAESERK----LLASGAPAPTGPFQYESFHVFDWDAYLEETGSEAAPAKCFK 195
            ..:..|....|...|..:|:    :|..|.| |.|.      ..:.|.:||||..:.|.|.|.||
  Rat   194 ENKQDGRILRGSQRARRKRRGDSAVLKQGLP-PKGK------KTWCWASYLEEEKAVAVPTKLFK 251

  Fly   196 QAQNPP--NNDFKIGMKLEALDPRNVTSTCIATVVGVLGSRLRLRLDGSDSQNDFWRLVDSTEIH 258
            :.|:.|  .|.||:|||||.:||.:.:..|:.||..|.|.|::|..||.....|||...|:.:||
  Rat   252 EHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIH 316

  Fly   259 AIGHCEKNGGMLQPPLGFRMNASSWPGYL--CKILNNAMVAPEEIFQPEPPEPEENLFKVGQKLE 321
            .:|.|||.|..|:||.|::....:|..||  ||    |..||:.:|:.:......:.|:||.|||
  Rat   317 PVGWCEKTGHKLRPPKGYKEEEFNWQSYLKTCK----AQAAPKSLFENQNITVIPSGFRVGMKLE 377

  Fly   322 AVDKKNPQLICCATVDAIKDDQIHVTFDGWRGAFDYWCNYRSRDIFPAGWCARSCHPM-QPPGHK 385
            |.|||:|.:||.|||..:.|::..|.||.|..::||||...|..|.|.|||......: .|||:.
  Rat   378 AADKKSPSIICVATVTDMVDNRFLVHFDNWDESYDYWCESNSPHIHPVGWCKEHRRTLITPPGYS 442

  Fly   386 SRMDSSSSKQRCPRPRYTVVAESEAMVPASPATAHFHPNCKGGPFINNSKLPCM-VTGPTYQTLA 449
            .....|..|          ..|....:|| ||.| |......| |....||..: ...|.:..:|
  Rat   443 HVKHFSWDK----------YLEETNSLPA-PARA-FKVKPPHG-FQKKMKLEAVDKRNPLFIRVA 494

  Fly   450 KLCLQEVLAASTDTQQLSKLLF------------ALEGDVHIVTAAGK-NFTVKIP-SPMRMKDD 500
            .:       |.||..:: |:.|            |...|:|.|....| ...::.| ||..:.:.
  Rat   495 TV-------ADTDDHRI-KVHFDGWSSCYDYWIDADSPDIHPVGWCSKTGHPLQAPLSPAELMEP 551

  Fly   501 ESLAQFIETLCTT--CRACANLISLVHETEECKKCANSRKRQL-TQS-ATPPSSPVLADKRNRQS 561
            .....     |.|  ||...:.               .:.|.| ||| |..|.|.:...|
  Rat   552 SETGG-----CPTLGCRGVGHF---------------KKSRYLGTQSGANCPYSEINLSK----- 591

  Fly   562 NSATTSPSEKIIKQELAVKSPVES----KSKTSTNNGKEPASQQNSNHSLNNNNNSASKSSNKV- 621
                    ::|....|:.:....|    :||.:..|....:.:....|:.|...:|..|..|:|
  Rat   592 --------DRIFPDRLSGEITPSSFSFPRSKRTDTNESSSSPETRDQHANNVKEDSEKKKENEVK 648

  Fly   622 ------VIKSEPNGANAQTSSTTQALRKVRFQHHANTNTNSSATNGNQDTSQTTHVSTSHCSSSS 680
                  |::.||..:..||....|||:.          ..:......|...|......:...:..
  Rat   649 TSAEAKVVREEPTPSVQQTQPPQQALKA----------PQAPQIQPAQQAPQAPQAQPTQQQAQQ 703

  Fly   681 TSSSTSLAGGSANTSTIGKYLAPLVAEVHPEQANVKPSNSYYKSPTTLSSSASLPTSVSTPFTGC 745
            ...:........         ||...:.||.|...:.:     .||...:..:.||..
  Rat   704 AQQAPQAPQAQP---------APQAPQTHPTQQQAQQA-----QPTQQQAQQAQPTQQ------- 747

  Fly   746 QSASSTALAAGGVTAAKAATAPAGAAATAGAS---PSYTAITSPVSTPTSALANSHLRSQPIDWT 807
            |.|...|.....|..:.....|.........|   |:...|      |.|.::.         |:
  Rat   748 QQAQQQAQRRSAVFLSFKPPIPCLPLRWEQQSKLLPTVAGI------PASRVSK---------WS 797

  Fly   808 IEEVIQYIESNDNSLAVHGDLFRKHEIDGKALLLLNSEMMMKYMGLKLGPALKICNLV 865
            .:||.::|:|.. ....||.:|:..:|||:|.||:....::|.|.:||||||||.|.:
  Rat   798 TDEVSEFIQSLP-GCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSI 854

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scm	NP_731385.1	zf-FCS	58..95	CDD:428958	6/41 (15%)
		MBT_dScm_rpt1	196..294	CDD:439097	41/101 (41%)
		MBT_dScm_rpt2	312..383	CDD:439100	32/71 (45%)
		SLED	418..522	CDD:463469	25/120 (21%)
		SAM_Scm	800..870	CDD:188977	25/66 (38%)
L3mbtl3	NP_001419245.1	MBT_L3MBTL3_rpt1	258..358	CDD:439122	42/103 (41%)
		MBT_L3MBTL3_rpt2	365..457	CDD:439125	37/101 (37%)
		MBT_L3MBTL3_rpt3	466..543	CDD:439128	17/85 (20%)
		SAM_Scm-like-3MBT3,4	793..858	CDD:188981	25/72 (35%)