Protein Alignment Scm and Sfmbt2

DIOPT Version :10

• Sequence 1: NP_731385.1
• Gene: Scm / 41168
• FlyBaseID: FBgn0003334
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: NP_001100834.2
• Gene: Sfmbt2 / 307106
• RGDID: 1305027
• Length: 890
• Species: Rattus norvegicus
• Alignment Length: 954
• Identity: 207/954 - (21%)
• Similarity: 325/954 - (34%)
• Gaps: 319/954 - (33%)

  Fly    64 TWCGEGKLPLQYVLPTQTGKKEFCSETCIAEFRKAYSKGACTQCDNVIR--DGAPNK-----EFC 121
            |.||: .|.|:|....:..:.:|..:..||:.   :..|.|||.:.|:|  |....|     ||.
  Rat    97 TTCGQ-LLLLRYCGYGEDRRADFWCDVIIADL---HPVGWCTQNNKVLRPPDAIKEKYADWEEFL 157

  Fly   122 SIMCMNKHQKKNCSTRHSG---GSASGKG------------LAESERKLLASGAPAPTGPFQY-- 169
            .      |:.....|..:.   |...|||            |.:|:            .||||
  Rat   158 I------HELTGSRTAPASLLEGPLRGKGPIDLITVDSLIELQDSQ------------NPFQYWI 204

  Fly   170 ---------------------ESFH----------------------------------VFDWDA 179
                                 ||:.                                  .|:|..
  Rat   205 VSVIENVGGRLRLRYVGLEHTESYDRWLFYLDYRLRPIGWCQEKKYRMDPPSELYYLKLPFEWKC 269

  Fly   180 YLEETGSEAA----PAKCFKQAQNPPNNDFKIGMKLEAL---DPRNVTSTCIATVVGVLGSR-LR 236
            .||:....||    |.:.||...:..::.|.:||:||.|   ||.::..   |||..|..|: .:
  Rat   270 ALEKALLAAAECPLPMEVFKDHADLGSHFFTVGMRLETLHINDPFHIYP---ATVTKVFNSQFFQ 331

  Fly   237 LRLDGSDSQNDFWRLV---DSTEIHAIGHCEKNGGMLQPPLGFRMNASSWPGYLCKILNNAMVAP 298
            :.:|...::.:...::   ||..|..:..|.|||..|.||.|:.....:|..|          ..
  Rat   332 VAIDDLRAETNGLTMLCHADSLGILPVQWCLKNGVNLAPPKGYSGQDFNWVDY----------HK 386

  Fly   299 EEIFQPEPPEPEENLFKVG----QKLEAVDKKNPQLICCATVDAIKDDQIHVTFDGWRGAF-DYW 358
            :...:..||...:|.|..|    .|||||:.|||..:|.|||.:::...:.:..:|..... :..
  Rat   387 QREAEGAPPYCFKNTFARGFAKNMKLEAVNPKNPGEVCVATVISVRGSLLWLRLEGVETPMPEII 451

  Fly   359 CNYRSRDIFPAGWCARSCHPMQPPGHKSRMDSSSSKQRCPRPRYTVVAESEAMVPA--------- 414
            .:..|.||||.|||..:.:|:..| :||   ||.||::    ..||..|..::.|.
  Rat   452 VDIDSMDIFPVGWCEANSYPLTTP-YKS---SSKSKKK----PITVPPEKPSLPPVPVENIPQEL 508

  Fly   415 --SPAT---------AHFHP------NCKGGPFINN---SKLPCMVTGPTYQTLAKLCLQEVLAA 459
              .|.|         .::.|      .|..|||:|.   |:||..| ||   ....|.|:|:|..
  Rat   509 CLPPQTDTAAGAANEKYYCPQLFVNHRCFSGPFLNKGRISELPQSV-GP---GKCVLVLKEILTM 569

  Fly   460 ST-----------DTQQLSKLLFALEGDVHIVTAAGKNF--TVKIPSPMRMKDDESLAQFIETLC 511
            .|           :.|.:....:..:.:|......||.:  .|||     ::..:.:..|.:.:|
  Rat   570 ITNAAYKPGRVLRELQLVEDPEWDFQEEVLKAKYRGKIYRAVVKI-----VRTADQVTSFCQQVC 629

  Fly   512 TTCRACANLISLVHETEEC-KKCANSRKRQLTQSATPPSSPVLADKRNRQSNSATTSPSEKIIKQ 575
            .....|.||.|.:..:|.| :.|:...|.:.|         ....||.|            |||.
  Rat   630 AKLECCPNLFSPLLISENCPENCSIRTKTKYT---------YYYGKRKR------------IIKP 673

  Fly   576 ELAVKSPVESKSKTSTNNGKEPASQQNSNHSLNNNNNSASKSSNKVVIKSEPNGANAQTSSTTQA 640
            .|.                             .:|..||.|.:.:
  Rat   674 PLG-----------------------------ESNTESAPKPTRR-------------------- 689

  Fly   641 LRKVRFQHHANTNTNSSATNGNQDTSQTTHVSTSHCSSSSTSSSTSLAGGSANTSTIGKYLAPLV 705
             ||.|...:......|||......::|.|.
  Rat   690 -RKRRKSIYVQKKRKSSAVAMPATSAQETE----------------------------------- 718

  Fly   706 AEVHPEQANVKPSNSYYKSPTTLSSSASLPTSVSTPFTGCQSASSTALAAGGVTAAKAATAPAGA 770
             |..||..:.....:.|    .:.:..:....|..|||..|.|......:|.|     ...|...
  Rat   719 -EDDPEALDTASEETGY----VVQNYKTQHVPVEMPFTRSQRAMILRKHSGAV-----KHPPVER 773

  Fly   771 AATAGASPSYTAITSPVSTPTSALANSH-----------LRSQPIDWTIEEVIQYIESNDNSLAV 824
            |....:..|..:..:....|...:..|.           |.|.|::|::.:|:::|:..|  .|.
  Rat   774 ARRVRSVHSTASSNNRNKVPLVRIEKSEDPRQSEEEKLILESNPLEWSVTDVVRFIKLTD--CAP 836

  Fly   825 HGDLFRKHEIDGKALLLLNSEMMMKYMGLKLGPALKICNLVNKV 868
            ...:|::.:|||:|||||....:.:.|.||||||:|:|:.:.:|
  Rat   837 LARIFQEQDIDGQALLLLTLPTVQECMELKLGPAIKLCHQIERV 880

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scm	NP_731385.1	zf-FCS	58..95	CDD:428958	9/30 (30%)
		MBT_dScm_rpt1	196..294	CDD:439097	27/104 (26%)
		MBT_dScm_rpt2	312..383	CDD:439100	25/75 (33%)
		SLED	418..522	CDD:463469	30/134 (22%)
		SAM_Scm	800..870	CDD:188977	26/69 (38%)
Sfmbt2	NP_001100834.2	MBT_SFMBT2_rpt1	70..163	CDD:439102	20/75 (27%)
		MBT	182..269	CDD:459242	10/98 (10%)
		MBT_SFMBT2_rpt3	297..389	CDD:439106	27/104 (26%)
		MBT	405..493	CDD:459242	32/95 (34%)
		SLED	527..641	CDD:463469	29/122 (24%)
		SAM_Scm-like-4MBT1,2	807..890	CDD:188980	27/76 (36%)