Protein Alignment Scm and Scml4

DIOPT Version :10

• Sequence 1: NP_731385.1
• Gene: Scm / 41168
• FlyBaseID: FBgn0003334
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: NP_001346193.1
• Gene: Scml4 / 268297
• MGIID: 2446140
• Length: 490
• Species: Mus musculus
• Alignment Length: 595
• Identity: 128/595 - (21%)
• Similarity: 192/595 - (32%)
• Gaps: 240/595 - (40%)

  Fly   351 WRGAFDYWCNYRSRDIFPAGWCARSCHPM------------------QPPGHKSRMD-------- 389
            |.|.    |:.....:.||  |....|.:                  :||.|.:|:.
Mouse    54 WSGL----CDQAVGPLLPA--CGLPSHAVRLAPAEMQTQRVPGRKRGRPPLHSTRVQMAVHNLYS 112

  Fly   390 -SSSS-------KQRCPRPRYTV------------------------VAESEAMVP------ASP 416
             |::|       |:|..:|||.:                        :.:..|.:|      |..
Mouse   113 ASAASVPAVTIPKKRGRKPRYKIKSPVLMTPLALSPPRSTPEPDLSSIPQDAATIPSLVVPEALT 177

  Fly   417 ATAHFHPNCKGGPFINNSKLPCMV--TGPTYQTLAKLCLQEVLAASTDTQQLSKLLFAL-----E 474
            ...:.:.....||::...||..:.  .||......   ||:.:.|..|.....:|:|:|     .
Mouse   178 VCLYINKQADVGPYLERRKLQQLPERLGPERPATV---LQQAVQACIDCAHQPRLVFSLVKQGYR 239

  Fly   475 GDVHIVTAA--GKNFTVKIPSPMRMKDDESLAQFIETLCTTCRA--CANLISLVHETEECKKCAN 535
            |::..|:|:  ||.....:|..      .|:...:..|...||:  |.||.|.:
Mouse   240 GELVSVSASFDGKQHLRSLPVV------NSVGYVLRFLTKLCRSLLCDNLFSHL----------- 287

  Fly   536 SRKRQLTQSATP-PSSPVLADKRNRQSNSATTSPSEKIIKQELAVKSPVESKSKTSTNNGKEPAS 599
                       | |.|...:||...:.:..|.|......::.||
Mouse   288 -----------PFPGSIGASDKAQEREDGRTESAKVATAEECLA--------------------- 320

  Fly   600 QQNSNHSLNNNNNSASKSSNKVVIKSEPNGANAQTSSTTQALRKVRFQHHANTNTNSSATNGNQD 664
                               |.|       |.|...         :.|.|..:
Mouse   321 -------------------NAV-------GMNRYA---------MDFSHRGS------------- 337

  Fly   665 TSQTTHVSTSHCSSSSTSSSTSLAGGSANTSTIGKYLAPLVAEVHPEQANVKPSNSYYKSPTTLS 729
               .||.|:.:  ...|...:.||||.| |:|.|....|:                    |:..|
Mouse   338 ---VTHSSSLY--KRLTCGDSHLAGGPA-TTTSGSRTNPV--------------------PSGGS 376

  Fly   730 SSASLPTSVSTPFTGCQSASSTALAAGGVTAAKAATAPAGAAATAGASPSYTAITSPVSTPTSAL 794
            ||..|....|:|                   .:..||..|.......||.......|.|
Mouse   377 SSPGLRLPASSP-------------------KRNGTAIEGNRCAPSPSPEVQDTRRPSS------ 416

  Fly   795 ANSHLRSQPIDWTIEEVIQYIESND-NSLAVHGDLFRKHEIDGKALLLLNSEMMMKYMGLKLGPA 858
                  ..|..||:|:|:::::..| .:|..|.:|||||||||.|||||.|:|:|||:|||||||
Mouse   417 ------RNPSTWTVEDVVRFVKDADPEALGPHVELFRKHEIDGNALLLLRSDMIMKYLGLKLGPA 475

  Fly   859 LKICNLVNKV 868
            ||:|..::|:
Mouse   476 LKLCYHIDKL 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scm	NP_731385.1	zf-FCS	58..95	CDD:428958
		MBT_dScm_rpt1	196..294	CDD:439097
		MBT_dScm_rpt2	312..383	CDD:439100	8/49 (16%)
		SLED	418..522	CDD:463469	26/114 (23%)
		SAM_Scm	800..870	CDD:188977	38/70 (54%)
Scml4	NP_001346193.1	RBR	83..142	CDD:465382	11/58 (19%)
		SLED	177..285	CDD:463469	26/116 (22%)
		SAM_Scm	416..487	CDD:188977	39/82 (48%)