Protein Alignment Scm and SCML4

DIOPT Version :9

• Sequence 1: NP_001247006.1
• Gene: Scm / 41168
• FlyBaseID: FBgn0003334
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: XP_016866166.1
• Gene: SCML4 / 256380
• HGNCID: 21397
• Length: 442
• Species: Homo sapiens
• Alignment Length: 511
• Identity: 118/511 - (23%)
• Similarity: 188/511 - (36%)
• Gaps: 174/511 - (34%)

  Fly   382 PGH--KSRMDSS----SSKQRCPRPRYTVVAESEAMVP--ASP----ATAHFHPNCKGGPFINNS 434
            ||:  |||:..:    |..:..|.|..:.:.:..|.||  |:|    ...:.:.....||::...
Human    77 PGYKIKSRVLMTPLALSPPRSTPEPDLSSIPQDAATVPSLAAPQALTVCLYINKQANAGPYLERK 141

  Fly   435 KLPCMVT--GPTYQTLAKLCLQEVLAASTDTQQLSKLLFAL-----EGDVHIVTAA--GKNFTVK 490
            |:..:..  ||...:..   ||:.:.|..|.....||:|:|     .|::..|:|:  ||.....
Human   142 KVQQLPEHFGPERPSAV---LQQAVQACIDCAHQQKLVFSLVKQGYGGEMVSVSASFDGKQHLRS 203

  Fly   491 IPSPMRMKDDESLAQFIETLCTTCRA--CANLISLVHETEECKKCANSRKRQLTQSATPPSSPVL 553
            :|..      .|:...:..|...||:  |.:|.|  |:... :.|:.|.|.|
Human   204 LPVV------NSIGYVLRFLAKLCRSLLCDDLFS--HQPFP-RGCSASEKVQ------------- 246

  Fly   554 ADKRNRQSNSATTSPSEKIIKQELAVKSPVESKSKTSTNNGKEPASQQNSNHSLNNNNNSASKSS 618
             :|...:..|..|..:|:.:...:.:
Human   247 -EKEEGRMESVKTVTTEEYLVNPVGM--------------------------------------- 271

  Fly   619 NKVVIKSEPNGANAQTSSTTQALRKVRFQHHANTNTNSSATNGNQDTSQTTHVSTSHCSSSSTSS 683
                     |..:..||::|       |.|..:.:.:||.                :|...: |.
Human   272 ---------NRYSVDTSAST-------FNHRGSLHPSSSL----------------YCKRQN-SG 303

  Fly   684 STSLAGGSANTSTIGKYLAPLVAEVHPEQANVKPSNSYYKSPTTLSSSASLPTSVSTPFTGCQSA 748
            .:.|.||.|.|:. |...:|: :...|....::|             .||.|...:|...|.:.|
Human   304 DSHLGGGPAATAG-GPRTSPM-SSGGPSAPGLRP-------------PASSPKRNTTSLEGNRCA 353

  Fly   749 SSTALAAGGVTAAKAATAPAGAAATAGASPSYTAITSPVSTPTSALANSHLRSQPIDWTIEEVIQ 813
            |                           |||..|  .....|.|        ..|..||:|:|:.
Human   354 S---------------------------SPSQDA--QDARRPRS--------RNPSAWTVEDVVW 381

  Fly   814 YIESND-NSLAVHGDLFRKHEIDGKALLLLNSEMMMKYMGLKLGPALKICNLVNKV 868
            :::..| .:|..|.:|||||||||.|||||.|:|:|||:|||||||||:|..::|:
Human   382 FVKDADPQALGPHVELFRKHEIDGNALLLLKSDMVMKYLGLKLGPALKLCYHIDKL 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scm	NP_001247006.1	zf-FCS	55..95	CDD:283998
		MBT	178..273	CDD:214723
		MBT	<312..382	CDD:214723	118/511 (23%)
		DUF3588	418..524	CDD:288954	26/116 (22%)
		SAM_Scm	800..870	CDD:188977	38/70 (54%)
		SAM	806..867	CDD:197735	36/61 (59%)
SCML4	XP_016866166.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	89	1.000	Domainoid score	I7837
eggNOG	1	0.900	-	-		E1_KOG3766
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123551at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12247
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	5	4.970