DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Calr and CRT3

DIOPT Version :9

Sequence 1:	NP_001262430.1	Gene:	Calr / 41166	FlyBaseID:	FBgn0005585	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_563816.1	Gene:	CRT3 / 837365	AraportID:	AT1G08450	Length:	424	Species:	Arabidopsis thaliana

Alignment Length:	411	Identity:	184/411 - (44%)
Similarity:	260/411 - (63%)	Gaps:	17/411 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 IVLLATVGFISAEVYLKENFDNENWEDTWIYS---KHPGKEFGKFVLTPGTFYNDAEADKGIQTS 69
            ::.||.:.|  :|::|:|:|:. .|:..|:.|   ::.||. |.|..|.|.:..|.: :|||||.
plant    19 VLTLAPLAF--SEIFLEEHFEG-GWKSRWVLSDWKRNEGKA-GTFKHTAGKWPGDPD-NKGIQTY 78

  Fly    70 QDARFYAASRKFDGFSNEDKPLVVQFSVKHEQNIDCGGGYVKLFDCSLDQTDMHGESPYEIMFGP 134
            .||:.||.|.|...|||:::.||||:|||.||:|:|||.|:||....::|....|::||.:||||
plant    79 NDAKHYAISAKIPEFSNKNRTLVVQYSVKIEQDIECGGAYIKLLSGYVNQKQFGGDTPYSLMFGP 143

  Fly   135 DICGPGTKKVHVIFSYKGKNHLISKDIRCKDDVYTHFYTLIVRPDNTYEVLIDNEKVESGNLEDD 199
            ||||..|||:|||.||:|:|:.|.||::|:.|...||||.|:|||.:|.||:||::.|.|::..|
plant   144 DICGTQTKKLHVIVSYQGQNYPIKKDLQCETDKLNHFYTFILRPDASYSVLVDNKEREFGSMYTD 208

  Fly   200 WDFLAPKKIKDPTATKPEDWDDRATIPDPDDKKPEDWDK-PEHIPDPDATKPEDWDDEMDGEWEP 263
            ||.|.|:|||...|.||||||||..|.||:|.|||.:|. |..|||..|.:|||||:|.:|.|||
plant   209 WDILPPRKIKVKNAKKPEDWDDREYIDDPNDVKPEGFDSIPREIPDRKAKEPEDWDEEENGLWEP 273

  Fly   264 PMIDNPEFKGEWQPKQLDNPNYKGAWEHPEIANPEYVPDDKLYLRKEICTLGFDLWQVKSGTIFD 328
            |.|.|..:||.|:.|::.||||||.|::|.|.|||:..|..||:.|.|...|.::||||:|:|||
plant   274 PKIPNSAYKGPWKAKRIKNPNYKGKWKNPWIDNPEFEDDPDLYVLKSIKYAGIEVWQVKAGSIFD 338

  Fly   329 NVLITDDVELAAKAAAEVKNTQAGEKKMKEAQDEVQRK-KDEEEAKKASDKDDEDEDDDDEEKDD 392
            |:||.||...|.....:........:|...|:.|.:|| :::|||:.|.::.:....:.|....|
plant   339 NILICDDPAYARSIVDDYFAQHRESEKELFAEAEKERKAREDEEARIAREEGERRRKERDHRYGD 403

  Fly   393 ESK-------QDKDQSEHDEL 406
            ..:       :|.....||||
plant   404 RRRRYKRPNPRDYMDDYHDEL 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Calr	NP_001262430.1	Calreticulin	25..332	CDD:278680	158/310 (51%)
CRT3	NP_563816.1	Calreticulin	34..342	CDD:278680	158/310 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	278	1.000	Domainoid score	I407
eggNOG	1	0.900	-	-		E1_KOG0674
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	428	1.000	Inparanoid score	I424
OMA	1	1.010	-	-		QHG53836
OrthoDB	1	1.010	-	-		D822188at2759
OrthoFinder	1	1.000	-	-		FOG0002317
OrthoInspector	1	1.000	-	-		otm3044
orthoMCL	1	0.900	-	-		OOG6_102266
Panther	1	1.100	-	-	O	PTHR11073
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1529
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840