Protein Alignment Calr and canx

DIOPT Version :9

• Sequence 1: NP_001262430.1
• Gene: Calr / 41166
• FlyBaseID: FBgn0005585
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_998613.1
• Gene: canx / 406757
• ZFINID: ZDB-GENE-040426-2797
• Length: 600
• Species: Danio rerio
• Alignment Length: 523
• Identity: 171/523 - (32%)
• Similarity: 231/523 - (44%)
• Gaps: 146/523 - (27%)

  Fly    20 EVYLKENFDNENWEDTWIYS--KHPG------KEFGKFVL-------TPGTFYNDAEADKGIQTS 69
            |.|..|.||....:. |:.|  |..|      |..||:.:       .||        |||:...
Zfish    76 EHYFAEAFDKGTLQG-WVLSQAKKDGIDEDIAKYDGKWEVEEMQDSKLPG--------DKGLVLK 131

  Fly    70 QDARFYAASR-KFDGFSNEDKPLVVQFSVKHEQNIDCGGGYVKLFDCS--LDQTDMHGESPYEIM 131
            ..|:.:|.|. ....|:.:.|||:||:.|..:..|||||.||||...:  ||..:...::||.||
Zfish   132 SKAKHHAISALLLRPFTFDTKPLIVQYEVNFQTGIDCGGAYVKLLSQTPDLDLEEFVDKTPYTIM 196

  Fly   132 FGPDICGPGTKKVHVIFSYKG-------KNHLISKDIRCKD---DVYTHFYTLIVRPDNTYEVLI 186
            ||||.||. ..|:|.||.:|.       :.|....|...:.   |..||.|||::.||||:|:||
Zfish   197 FGPDKCGE-DYKLHFIFRHKNPKTGEFEEKHAKKPDSDLRSYYTDKKTHLYTLVLNPDNTFEILI 260

  Fly   187 DNEKVESGNLEDDW--DFLAPKKIKDPTATKPEDWDDRATIPDPDDKKPEDW------------- 236
            |...|.||:|.:|.  ....|.:|:||...||||||:|..|.|||..|||||
Zfish   261 DQTVVNSGSLLNDVTPPVNPPAEIEDPDDHKPEDWDERPKIQDPDAVKPEDWDEDAPAKIADEDA 325

  Fly   237 --------DKPEHIPDPDATKPEDWDDEMDGEWEP-------------------PMIDNPEFKGE 274
                    |:||:|.||||.||||||::||||||.                   ||||||.:||:
Zfish   326 VKPDGWLDDEPEYISDPDAVKPEDWDEDMDGEWEAPQIPNPVCETAPGCGAWERPMIDNPNYKGK 390

  Fly   275 WQPKQLDNPNYKGAWEHPEIANPEYVPDDKLYLRKEICTLGFDLWQVKSGTIFDNVLITDD---- 335
            |:...:|||||:|.|:..:|.||::..|...:.......:|.:||.:.|...|||..||.|
Zfish   391 WKSPMIDNPNYQGVWKPRKIPNPDFFEDLHPFRMTPFSAVGLELWSMSSDIFFDNFFITSDRNVA 455

  Fly   336 ---------VELAAKAAAE---------------------------------------------- 345
                     ::.||:.|||
Zfish   456 ERWANDGWGLKKAAEGAAEPGLVNQMITAAEERPWLWIVYVLTVALPLVLIIVFCCTGKKSSAST 520

  Fly   346 ----VKNTQAGEKKMKEAQDEVQRKKDEEEAKKASDKD---DEDEDDDDEEKDDESKQDKDQSEH 403
                .|.|...:..:||..:|.:.|.:|.||||:.::|   |.|.||..|..|.:.....::||.
Zfish   521 PAAKYKKTDEPQPDVKEEAEEEEAKDEEPEAKKSEEEDSTGDGDGDDTAENGDKDDNTSNEKSED 585

  Fly   404 DEL 406
            |.|
Zfish   586 DIL 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Calr	NP_001262430.1	Calreticulin	25..332	CDD:278680	139/376 (37%)
canx	NP_998613.1	Calreticulin	79..448	CDD:278680	139/378 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R163
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940