Protein Alignment Calr and canx

DIOPT Version :10

• Sequence 1: NP_524293.2
• Gene: Calr / 41166
• FlyBaseID: FBgn0005585
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_998613.1
• Gene: canx / 406757
• ZFINID: ZDB-GENE-040426-2797
• Length: 600
• Species: Danio rerio
• Alignment Length: 523
• Identity: 171/523 - (32%)
• Similarity: 231/523 - (44%)
• Gaps: 146/523 - (27%)

  Fly    20 EVYLKENFDNENWEDTWIYS--KHPG------KEFGKFVL-------TPGTFYNDAEADKGIQTS 69
            |.|..|.||....:. |:.|  |..|      |..||:.:       .||        |||:...
Zfish    76 EHYFAEAFDKGTLQG-WVLSQAKKDGIDEDIAKYDGKWEVEEMQDSKLPG--------DKGLVLK 131

  Fly    70 QDARFYAASR-KFDGFSNEDKPLVVQFSVKHEQNIDCGGGYVKLFDCS--LDQTDMHGESPYEIM 131
            ..|:.:|.|. ....|:.:.|||:||:.|..:..|||||.||||...:  ||..:...::||.||
Zfish   132 SKAKHHAISALLLRPFTFDTKPLIVQYEVNFQTGIDCGGAYVKLLSQTPDLDLEEFVDKTPYTIM 196

  Fly   132 FGPDICGPGTKKVHVIFSYKG-------KNHLISKDIRCKD---DVYTHFYTLIVRPDNTYEVLI 186
            ||||.||. ..|:|.||.:|.       :.|....|...:.   |..||.|||::.||||:|:||
Zfish   197 FGPDKCGE-DYKLHFIFRHKNPKTGEFEEKHAKKPDSDLRSYYTDKKTHLYTLVLNPDNTFEILI 260

  Fly   187 DNEKVESGNLEDDW--DFLAPKKIKDPTATKPEDWDDRATIPDPDDKKPEDW------------- 236
            |...|.||:|.:|.  ....|.:|:||...||||||:|..|.|||..|||||
Zfish   261 DQTVVNSGSLLNDVTPPVNPPAEIEDPDDHKPEDWDERPKIQDPDAVKPEDWDEDAPAKIADEDA 325

  Fly   237 --------DKPEHIPDPDATKPEDWDDEMDGEWEP-------------------PMIDNPEFKGE 274
                    |:||:|.||||.||||||::||||||.                   ||||||.:||:
Zfish   326 VKPDGWLDDEPEYISDPDAVKPEDWDEDMDGEWEAPQIPNPVCETAPGCGAWERPMIDNPNYKGK 390

  Fly   275 WQPKQLDNPNYKGAWEHPEIANPEYVPDDKLYLRKEICTLGFDLWQVKSGTIFDNVLITDD---- 335
            |:...:|||||:|.|:..:|.||::..|...:.......:|.:||.:.|...|||..||.|
Zfish   391 WKSPMIDNPNYQGVWKPRKIPNPDFFEDLHPFRMTPFSAVGLELWSMSSDIFFDNFFITSDRNVA 455

  Fly   336 ---------VELAAKAAAE---------------------------------------------- 345
                     ::.||:.|||
Zfish   456 ERWANDGWGLKKAAEGAAEPGLVNQMITAAEERPWLWIVYVLTVALPLVLIIVFCCTGKKSSAST 520

  Fly   346 ----VKNTQAGEKKMKEAQDEVQRKKDEEEAKKASDKD---DEDEDDDDEEKDDESKQDKDQSEH 403
                .|.|...:..:||..:|.:.|.:|.||||:.::|   |.|.||..|..|.:.....::||.
Zfish   521 PAAKYKKTDEPQPDVKEEAEEEEAKDEEPEAKKSEEEDSTGDGDGDDTAENGDKDDNTSNEKSED 585

  Fly   404 DEL 406
            |.|
Zfish   586 DIL 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Calr	NP_524293.2	Calreticulin	25..332	CDD:459737	139/376 (37%)
canx	NP_998613.1	Calreticulin	79..448	CDD:459737	139/378 (37%)