Protein Alignment Calr and crt-1

DIOPT Version :9

• Sequence 1: NP_001262430.1
• Gene: Calr / 41166
• FlyBaseID: FBgn0005585
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_504575.1
• Gene: crt-1 / 178997
• WormBaseID: WBGene00000802
• Length: 395
• Species: Caenorhabditis elegans
• Alignment Length: 401
• Identity: 241/401 - (60%)
• Similarity: 293/401 - (73%)
• Gaps: 11/401 - (2%)

  Fly     8 IVLLATVGFISAEVYLKENFDNENWEDTWIYSKHPGKEFGKFVLTPGTFYNDAEADKGIQTSQDA 72
            :.|||.|..:|||||.||.|::.:||..|:.|||. .:||.|.|:.|.|::....|:||||||||
 Worm     4 LCLLAIVAVVSAEVYFKEEFNDASWEKRWVQSKHK-DDFGAFKLSAGKFFDVESRDQGIQTSQDA 67

  Fly    73 RFYAASRKFD-GFSNEDKPLVVQFSVKHEQNIDCGGGYVKLFDCSLDQTDMHGESPYEIMFGPDI 136
            :||:.:.||| .|||:.|.||:|::|||||.|||||||||:.....|..|.|||:||.:||||||
 Worm    68 KFYSRAAKFDKDFSNKGKTLVIQYTVKHEQGIDCGGGYVKVMRADADLGDFHGETPYNVMFGPDI 132

  Fly   137 CGPGTKKVHVIFSYKGKNHLISKDIRCKDDVYTHFYTLIVRPDNTYEVLIDNEKVESGNLEDDWD 201
            ||| |::||||.:|||:|.||.|:|.||.|..||.||||:..||||||.||.|..::|:||:|||
 Worm   133 CGP-TRRVHVILNYKGENKLIKKEITCKSDELTHLYTLILNSDNTYEVKIDGESAQTGSLEEDWD 196

  Fly   202 FLAPKKIKDPTATKPEDWDDRATIPDPDDKKPEDWDKPEHIPDPDATKPEDWDDEMDGEWEPPMI 266
            .|..||||||.|.||||||:|..|.|.:|.|||||:||||||||||.||||||||||||||||||
 Worm   197 LLPAKKIKDPDAKKPEDWDEREYIDDAEDAKPEDWEKPEHIPDPDAKKPEDWDDEMDGEWEPPMI 261

  Fly   267 DNPEFKGEWQPKQLDNPNYKGAWEHPEIANPEYVPDDKLYLRKEICTLGFDLWQVKSGTIFDNVL 331
            ||||:||||:|||:.||.|||.|.||||.||||.|||:||..:....:|||||||||||||||::
 Worm   262 DNPEYKGEWKPKQIKNPAYKGKWIHPEIENPEYTPDDELYSYESWGAIGFDLWQVKSGTIFDNII 326

  Fly   332 ITDDVELAAKAAAEV-KNTQAGEKKMKEAQDEVQRKKDEEEAKKASDKDDEDEDDDDEEKDDESK 395
            |||.||.|...|||. ...:..||:.||..||..||.:||..|||.::.:..:|||:|||::|
 Worm   327 ITDSVEEAEAHAAETFDKLKTVEKEKKEKADEETRKAEEEARKKAEEEKEAKKDDDEEEKEEE-- 389

  Fly   396 QDKDQSEHDEL 406
                 ..||||
 Worm   390 -----EGHDEL 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Calr	NP_001262430.1	Calreticulin	25..332	CDD:278680	198/307 (64%)
crt-1	NP_504575.1	Calreticulin	19..327	CDD:278680	199/309 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	314	1.000	Domainoid score	I700
eggNOG	1	0.900	-	-		E1_KOG0674
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37911
Inparanoid	1	1.050	507	1.000	Inparanoid score	I727
Isobase	1	0.950	-	0	Normalized mean entropy	S1196
OMA	1	1.010	-	-		QHG53836
OrthoDB	1	1.010	-	-		D351852at33208
OrthoFinder	1	1.000	-	-		FOG0002317
OrthoInspector	1	1.000	-	-		oto17640
orthoMCL	1	0.900	-	-		OOG6_102266
Panther	1	1.100	-	-	LDO	PTHR11073
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R163
SonicParanoid	1	1.000	-	-		X1529
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.860