Protein Alignment Calr and cnx-1

DIOPT Version :9

• Sequence 1: NP_001262430.1
• Gene: Calr / 41166
• FlyBaseID: FBgn0005585
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_499176.1
• Gene: cnx-1 / 176390
• WormBaseID: WBGene00000567
• Length: 619
• Species: Caenorhabditis elegans
• Alignment Length: 462
• Identity: 144/462 - (31%)
• Similarity: 205/462 - (44%)
• Gaps: 119/462 - (25%)

  Fly    61 EADKGIQTSQDARFYAASRKFD-GFSNEDKPLVVQFSVKHEQNIDCGGGYVKLFD--CSLDQTDM 122
            |.|.|:.....||.:|.:.|.: .|:.:....|||:.:|.|:..:|||||:||..  ...|..:.
 Worm   107 EGDLGLIVKTKARHHAIAAKLNTPFAFDANTFVVQYDIKFEEGQECGGGYLKLLSEGAEKDLANF 171

  Fly   123 HGESPYEIMFGPDICGPGTKKVHVIFSYKGK-NHLISK---------DIRCKDDVYTHFYTLIVR 177
            ..::.|.||||||.|| .|.|||:||.||.. |..||:         .....||..||.:||:|:
 Worm   172 QDKTAYTIMFGPDKCG-ATGKVHLIFRYKNPINGTISEYHANQPTTIGSTYWDDHNTHLFTLVVK 235

  Fly   178 PDNTYEVLIDNEKVESGNLEDDWD--FLAPKKIKDPTATKPEDWDDRATIPDPDDKKPEDWD--- 237
            |...|.|.:|.:.:..||:..|..  ...||:|.|.|..||.|||:|..|.|....||:|||
 Worm   236 PTGEYSVSVDGKSLYYGNMMSDVTPALTPPKQIFDETDLKPVDWDERENIEDESAVKPDDWDENE 300

  Fly   238 ----------KP--------EHIPDPDATKPEDWDDEMDGEWEPPMIDNPEFK-----GEWQPKQ 279
                      ||        |.|.||:|.||:|||::|||.||.|:||||..|     |.|:...
 Worm   301 PQSVVDEAATKPYDWNEEENELIADPEAKKPQDWDEDMDGSWEAPLIDNPACKGLSGCGTWKAPT 365

  Fly   280 LDNPNYKGAWEHPEIANPEY-------VPDDKLYLRKE-------ICTLGFDLWQVKSGTIFDNV 330
            :.||.|||.|..|:|:||.:       :.|:..|...:       |..:|.::|.:....:|||:
 Worm   366 IKNPKYKGKWIRPKISNPAFKGKWTARLIDNPNYFEPKPFAGLAPITAVGIEMWTMSENILFDNI 430

  Fly   331 LITDDVELAA---------------KAAAEVKNTQAGEKKMKEAQDE------------------ 362
            |||...|.::               :.||...|.....:::.:|.:|
 Worm   431 LITSSEEDSSDVAKQTFYVKQKEEYRLAAATGNGNGFFQQIIDATNEKPWLWAVYILCVLLPLVA 495

  Fly   363 -------VQRKKDEEEAKKASDKDDEDED------DDDEEK---DDE-------------SKQDK 398
                   .|.|.....||| ||....|:|      |||||:   |:|             :.:.:
 Worm   496 IGVFCFGKQSKPTPNFAKK-SDAYSADDDRVPNLVDDDEEEIIGDEEDDVNQPGPSGSQSNPEPQ 559

  Fly   399 DQSEHDE 405
            |:.|:.|
 Worm   560 DEEENAE 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Calr	NP_001262430.1	Calreticulin	25..332	CDD:278680	116/325 (36%)
cnx-1	NP_499176.1	Calreticulin	61..432	CDD:278680	116/325 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R163
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.940