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Protein Alignment CG8319 and ZNF177

DIOPT Version :10

Sequence 1:	NP_649920.2	Gene:	CG8319 / 41165	FlyBaseID:	FBgn0037722	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_001166122.1	Gene:	ZNF177 / 7730	HGNCID:	12966	Length:	481	Species:	Homo sapiens

Alignment Length:	422	Identity:	114/422 - (27%)
Similarity:	174/422 - (41%)	Gaps:	86/422 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 EMVKT---------CAD--VQLDPDDAM--------------------PQKMCISCVHDAR---- 63
            |.:||         |||  .||.|.|.:                    |.:..:.|.|..:
Human    69 EQLKTDERGILQGDCADWETQLKPKDTIAMQNIPGGKTSNGINTAENQPGEHSLECNHCGKFRKN 133

  Fly    64 TAYGFKRRCEENYKKFYLAILNGQVIKDEPNEEDFLFIENPDKGNLE---AKKKLNKE--IKKTH 123
            |.:...|.|:.  :|.|..|...:|..........:.|...:| .||   .:|..|:|  ::|..
Human   134 TRFICTRYCKG--EKCYKYIKYSKVFNHPSTLRSHVSIHIGEK-TLEFTDCRKAFNQESSLRKHL 195

  Fly   124 QT-------------------ASRTTKSSITTSRAGRQLR--------SIKNQT------FKCEL 155
            :|                   :|.:.:..|.|...|.:..        |:..:|      .:|..
Human   196 RTPTGQKFQEYEQCDMSFSLHSSCSVREQIPTGEKGDECSDYGKISPLSVHTKTGSVEEGLECNE 260

  Fly   156 CIKQFKRQINLLDHMKVHSNS--HVCQNCEERFLFKADLDNHQCYRNSNSTVECPECLKVFSSTQ 218
            ..|.|...::|.:.::.||..  :.|.:|.:.|:|::.|..|..........||..|.|.||.:.
Human   261 HEKTFTDPLSLQNCVRTHSGEMPYECSDCGKAFIFQSSLKKHMRSHTGEKPYECDHCGKSFSQSS 325

  Fly   219 SLDSHKCKDMQERSPFQCPHCQQAFTREQNLKAHLLIHAESKQGNGPHKCSYCQTGFFNKSALKV 283
            .|:.||.....|: |:.|..|.:|||...:|:.|:..|.    |..|::||.|...|.::|:||.
Human   326 HLNVHKRTHTGEK-PYDCKECGKAFTVPSSLQKHVRTHT----GEKPYECSDCGKAFIDQSSLKK 385

  Fly   284 HIHAHMGERPHACPFCVSNFRSKQALKVHIRIHTGEKPYQCPHCPKTFSDNNNLAKHRRRHSDER 348
            |..:|.||:|:.|..|..:|.:...|.||.|.|||||.|:|..|.|.|.:::.|..|.|.|:.|:
Human   386 HTRSHTGEKPYECNQCGKSFSTGSYLIVHKRTHTGEKTYECKECGKAFRNSSCLRVHVRTHTGEK 450

  Fly   349 PYKCSICLQDFREKHHLKRHFLGKHRDGDQKL 380
            ||||..|.:.|....:|..|   |.....|||
Human   451 PYKCIQCEKAFSTSTNLIMH---KRIHNGQKL 479

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.