back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8319 and ZNF84

DIOPT Version :10

Sequence 1:	NP_649920.2	Gene:	CG8319 / 41165	FlyBaseID:	FBgn0037722	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_003419.3	Gene:	ZNF84 / 7637	HGNCID:	13159	Length:	738	Species:	Homo sapiens

Alignment Length:	325	Identity:	99/325 - (30%)
Similarity:	157/325 - (48%)	Gaps:	34/325 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 VHDARTAYGFKRRCEENYKKF--YLAILNGQVIKDEPNEEDFLFIENPDKGNLEAKKKLNKEIKK 121
            :|.....|    .|.|..|.|  ..:::|.|  :....|:        ..|.::..|..:::...
Human   396 IHTGEKPY----ECSECRKAFRERSSLINHQ--RTHTGEK--------PHGCIQCGKAFSQKSHL 446

  Fly   122 THQTASRTTKSSITTSRAG----RQLRSIKNQ-------TFKCELCIKQFKRQINLLDHMKVHSN 175
            .....:.|.:.....|:.|    |:.:.:::|       .::|..|.|.|..:::|.:|.::|:.
Human   447 ISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTG 511

  Fly   176 S--HVCQNCEERFLFKADLDNHQCYRNSNSTVECPECLKVFSSTQSLDSHKCKDMQERSPFQCPH 238
            .  :||..|.:.|..|:.|.:||.........||.||.|.|....||.:|:.....|: |::|..
Human   512 EKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEK-PYECRD 575

  Fly   239 CQQAFTREQNLKAHLLIHAESKQGNGPHKCSYCQTGFFNKSALKVHIHAHMGERPHACPFCVSNF 303
            |::||:::..|..|..||.    |..|::||.|:..||.||.|..|:..|.||:|:.|..|...|
Human   576 CEKAFSQKSQLNTHQRIHT----GEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAF 636

  Fly   304 RSKQALKVHIRIHTGEKPYQCPHCPKTFSDNNNLAKHRRRHSDERPYKCSICLQDFREKHHLKRH 368
            |.|.:|..|.||||||||::|..|.|.||..::|..|:|.|:.|:||.||.|.:.|.:|..|..|
Human   637 REKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNH 701

Fly 369 368
Human 702 701

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.