DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8319 and E4f1

DIOPT Version :9

Sequence 1:	NP_649920.2	Gene:	CG8319 / 41165	FlyBaseID:	FBgn0037722	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_001171975.1	Gene:	E4f1 / 681359	RGDID:	1596731	Length:	783	Species:	Rattus norvegicus

Alignment Length:	169	Identity:	56/169 - (33%)
Similarity:	85/169 - (50%)	Gaps:	5/169 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   204 TVECPECLKVFSSTQSLDSHKCKDMQERSPFQCPHCQQAFTREQNLKAHLLIHAESKQGNGPHKC 268
            |..|.:|.:.|.|..:|::||...:..| ||.|..|.:||.:...||.|..:|...::    .:|
  Rat   433 THPCSQCSETFPSAATLEAHKRGHIGPR-PFTCTQCGKAFPKAYLLKKHQEVHVHERR----FRC 492

  Fly   269 SYCQTGFFNKSALKVHIHAHMGERPHACPFCVSNFRSKQALKVHIRIHTGEKPYQCPHCPKTFSD 333
            ..|...:...:.::.|...|..|||..||.|...:::|.|.:||.|.|..|||:.|..|.:.|.:
  Rat   493 GDCGKLYKTIAHVRGHRRVHSDERPFPCPQCGKRYKTKNAQQVHFRTHLEEKPHVCQFCSRGFRE 557

  Fly   334 NNNLAKHRRRHSDERPYKCSICLQDFREKHHLKRHFLGK 372
            ..:|.:|.|.|:.|:|:||..|.:.|.|...|.||...|
  Rat   558 KGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTK 596

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8319	NP_649920.2	zf-AD	4..79	CDD:285071
		COG5048	<153..368	CDD:227381	53/163 (33%)
		C2H2 Zn finger	153..173	CDD:275368
		C2H2 Zn finger	179..196	CDD:275368
		C2H2 Zn finger	207..227	CDD:275370	7/19 (37%)
		C2H2 Zn finger	236..256	CDD:275368	7/19 (37%)
		C2H2 Zn finger	268..288	CDD:275368	3/19 (16%)
		C2H2 Zn finger	296..316	CDD:275368	8/19 (42%)
		zf-H2C2_2	308..332	CDD:290200	10/23 (43%)
		zf-C2H2	322..344	CDD:278523	6/21 (29%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		C2H2 Zn finger	352..368	CDD:275368	5/15 (33%)
E4f1	NP_001171975.1	COG5048	193..594	CDD:227381	55/165 (33%)
		C2H2 Zn finger	195..215	CDD:275368
		zf-C2H2	221..243	CDD:278523
		C2H2 Zn finger	223..243	CDD:275368
		zf-H2C2_2	235..258	CDD:290200
		C2H2 Zn finger	251..269	CDD:275368
		C2H2 Zn finger	436..456	CDD:275368	7/19 (37%)
		zf-H2C2_2	449..471	CDD:290200	8/22 (36%)
		zf-C2H2	462..484	CDD:278523	8/21 (38%)
		C2H2 Zn finger	464..484	CDD:275368	7/19 (37%)
		C2H2 Zn finger	492..512	CDD:275368	3/19 (16%)
		zf-H2C2_2	504..529	CDD:290200	8/24 (33%)
		C2H2 Zn finger	520..540	CDD:275368	8/19 (42%)
		C2H2 Zn finger	548..568	CDD:275368	6/19 (32%)
		zf-H2C2_2	560..584	CDD:290200	9/23 (39%)
		C2H2 Zn finger	576..595	CDD:275368	7/18 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910