DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8319 and znf995

DIOPT Version :9

Sequence 1:	NP_649920.2	Gene:	CG8319 / 41165	FlyBaseID:	FBgn0037722	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	XP_017209820.1	Gene:	znf995 / 563697	ZFINID:	ZDB-GENE-080215-13	Length:	358	Species:	Danio rerio

Alignment Length:	300	Identity:	92/300 - (30%)
Similarity:	136/300 - (45%)	Gaps:	26/300 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 IKDEPNE---EDFLFIENPDKGNLEAKKKLNKEIKKTHQ------------TASRTTKSSITTSR 138
            ||:|..:   |:...::..|   |:.:..|....:||||            |..:.|.:..|.||
Zfish     4 IKEESEDVKIEETFTVKQED---LQEQTDLMLLKEKTHQQNEMEEKQQDMTTDEKPTLTKKTLSR 65

  Fly   139 AGRQLRSIKNQTFKCELCIKQFKRQINLLDHMKVHS--NSHVCQNCEERFLFKADLDNHQCYRNS 201
             ||..:|.....|.|:.|.|.|.::..|..|::.|:  .::.|:.|.:.|....:|..|......
Zfish    66 -GRPRKSKPRCNFSCKQCGKSFSQKPKLDVHIRDHTREKAYTCKQCGKSFYNTRNLTVHMRIHTG 129

  Fly   202 NSTVECPECLKVFSSTQSLDSHKCKDMQERSPFQCPHCQQAFTREQNLKAHLLIHAESKQGNGPH 266
            .....|.:|.|.|..|.:|..|......|| |:.|..|.::|....||..|:.||.    |..|:
Zfish   130 ERPYTCQQCGKSFHKTGNLTVHLRIHTGER-PYTCQQCGKSFQTTGNLTVHMRIHT----GEKPY 189

  Fly   267 KCSYCQTGFFNKSALKVHIHAHMGERPHACPFCVSNFRSKQALKVHIRIHTGEKPYQCPHCPKTF 331
            .|..|...:...|.|:||:..|.|.|...|..|..:|..||.|.:|:|||||||||.|..|.|:|
Zfish   190 SCPQCGKSYSQNSNLEVHMRTHNGGRTFVCTQCGKSFVKKQNLDLHMRIHTGEKPYTCTECGKSF 254

  Fly   332 SDNNNLAKHRRRHSDERPYKCSICLQDFREKHHLKRHFLG 371
            ...:.|..|...|:.|:|:.|:.|.:.|....:|:.|..|
Zfish   255 PYKSTLKHHMIVHTGEKPFACAQCGKSFTCNANLRNHMNG 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8319	NP_649920.2	zf-AD	4..79	CDD:285071
		COG5048	<153..368	CDD:227381	70/216 (32%)
		C2H2 Zn finger	153..173	CDD:275368	6/19 (32%)
		C2H2 Zn finger	179..196	CDD:275368	4/16 (25%)
		C2H2 Zn finger	207..227	CDD:275370	7/19 (37%)
		C2H2 Zn finger	236..256	CDD:275368	6/19 (32%)
		C2H2 Zn finger	268..288	CDD:275368	6/19 (32%)
		C2H2 Zn finger	296..316	CDD:275368	8/19 (42%)
		zf-H2C2_2	308..332	CDD:290200	14/23 (61%)
		zf-C2H2	322..344	CDD:278523	7/21 (33%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		C2H2 Zn finger	352..368	CDD:275368	4/15 (27%)
znf995	XP_017209820.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910